Calling all biotechnology startups focusing on sustainable feedstocks, commercially viable yields, and purpose fit microbes. Photo via Getty Images

A Houston organization — freshly funded by a $700,000 U.S. Economic Development Administration’s “Build to Scale” grant — is seeking its first accelerator cohort of industrial biology startups.

Founded by Houston-based First Bight Ventures, the BioWell has launched a virtual accelerator program that will provide programming, networking, mentorship, and financial resources to its inaugural cohort of 10 bioindustrial startups. The selected companies will also have access to specialized pilot bioproduction infrastructure throughout the nine-month program.

“BioWell equips startups with more than just capital. We provide a foundation for breakthrough innovations by combining access to cutting-edge bioproduction facilities with expertise that nurtures scalability. This comprehensive support is crucial for transforming pioneering ideas into market-ready solutions that can address pressing global challenges,” Carlos Estrada, head of venture acceleration at BioWell, says in a news release.

Applications for the program are open until May 15, and the cohort will be announced in June. Specifically, BioWell is seeking seed or pre-seed startup applicants that have a technology readiness level of 3 to 5, focusing on areas including low-cost and sustainable feedstocks, commercially viable yields, and purpose fit microbes.

“During our selection process, we'll prioritize startups that demonstrate a commitment to not only hitting milestones but also to building sustainable revenue streams for long-term survival. This phase necessitates keen awareness of market dynamics, customer demands, and sound financial management,” adds First Bight Ventures and BioWell Founder Veronica Wu.

In December, BioWell secured $741,925 of the $53 million doled out as a part of the "Build to Scale" Grant program that the U.S. Economic Development Administration, a division of the U.S. Department of Commerce, has established. First Bight was one of 60 organizations to receive funding.

Ex-Apple exec Wu founded First Bight Ventures in Houston in 2022 after relocating from Silicon Valley and seeing the region's potential for biotech.

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This article originally ran on InnovationMap.

First Bight Venture's BioWell has received a $741,925 grant to continue supporting bioindustrial startups. Photo via Getty Images

Houston nonprofit accelerator receives grant funding to advance bioindustrial startups

the biowell

A Houston-based nonprofit accelerator that works with early-stage synthetic biology startups has secured nearly $750,000 to support its mission.

First Bight Ventures' accelerator, BioWell, secured $741,925 of the $53 million doled out as a part of the "Build to Scale" Grant program that the U.S. Economic Development Administration, a division of the U.S. Department of Commerce, has established. First Bight was one of 60 organizations to receive funding.

The funding will support the BioWell's mission to establish a "vibrant bioeconomy" by helping startups scale and commercialize "through access to a unique combination of pilot bioproduction infrastructure," according to a news release from First Bight.

"Startups at BioWell will gain access to a robust ecosystem, expertise, mentorship, and financial resources essential for successfully commercializing their bio-industrial innovations," BioWell Executive Director Paul Palmer says in the release.

The BioWell is still working toward establishing a physical space and has worked out of the East End Maker Hub in the meantime. The organization has partnered with Urban Partnerships Community Development Corporation, or UP CDC, which led the application process on this federal grant.

"BioWell chose to partner with UP CDC for the EDA grant, to continue the successful model that UP CDC has created at the East End Maker Hub for advanced manufacturing. UP CDC looks forward to continuing our partnership with BioWell in the UP CDC's BioCity project that will position Houston at the forefront of bio-manufacturing," UP CDC's CEO Patrick Ezzell says in the release.

First Bight Ventures Founder Veronica Wu established the BioWell to target high-potential startups, which usually have to overcome lack of funding challenges early on.

"Often times, early-stage startups gain momentum and hit important milestones, but ultimately find themselves heading toward the 'Valley of Death,' where progress is made on their enterprise, but no sufficient revenue is generated for the company's stability and longevity," Wu says in the release. "This 'Build to Scale' program's support will help offset these inevitable challenges in our bio-industrial space."

She shares more about her mission for First Bight Ventures on the Houston Innovators Podcast. Listen to the interview from March below.

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This article originally ran on InnovationMap.

Algenesis bills its patented Soleic technology as the world’s first renewable, high-performance, fully biodegradable, and backyard-compostable polyurethane made from plants and algae. Photo via AlgenesisMaterials.com

Houston VC invests in early stage California biodegradable plastics startup

seed funding

Houston-based venture capital firm First Bight Ventures led a $5 million seed round for Encinitas, California-based startup Algenesis, a developer of biodegradable plastics.

Algenesis bills its patented Soleic technology as the world’s first renewable, high-performance, fully biodegradable, and backyard-compostable polyurethane made from plants and algae. Each year, 25 million tons of hard-to-recycle polyurethane are produced for the footwear, medical, and textile industries. Polyurethane, typically made from petroleum, usually ends up as landfill waste or environmental microplastics.

Algenesis says Soleic can biodegrade in compost within a matter of months and does not contain harmful PFAS chemicals found in other plastics.

Algenesis says the new funding will enable it to expand beyond soft-foam applications, such as midsoles and insoles for footwear, and into injection-molded products such as smartphone cases along with waterproof textiles.

Aside from First Bight Ventures, investors in the seed round are Singapore-based Circulate Capital, India-based MIH Capital, Chesapeake, Virginia-based Diamond Sports Group, and France-based Rhinoshield.

The investment comes on the heels of a $5 million grant Algenesis received from the U.S. Department of Energy to scale up production of biochemicals.

“To save our planet and ourselves, we must move away from petroleum-based plastics and toward bio-based alternatives. Algenesis is clearly at the forefront of making this possible,” says Veronica Wu, founder of First Bight Ventures.

First Bight, which launched in 2022, invests in early-stage startups working on synthetic biology.

“First Bight is investing to bring the best and the brightest — and most promising — synthetic biology startups from around the country to Houston,” Wu said last year.

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Houston geothermal companies secure more than $45M in DOE funding

geothermal boost

Three Houston-based companies—Fervo Energy, Quaise Energy and XGS Energy—have been selected by the U.S. Department of Energy to advance geothermal technologies and field tests.

Combined, the companies will receive more than $45 million in funding from the DOE's Next-Generation Geothermal Field Tests and Geothermal Resource Characterization and Confirmation initiative. The projects were among 21 selected from around the country to receive a total of $99 million.

Fervo was selected to conduct two projects under the initiative for approximately $20 million in funding. For the first project, the geothermal unicorn, which achieved first power at its flagship geothermal plant last week, will drill and complete enhanced geothermal systems (EGS) wells in Elmore County, Idaho, and will deploy high-temperature seismic monitoring technology at record-high temperatures at or above 200°C.

For the second project, the company will conduct an appraisal drilling campaign at a "high-priority" site in Humboldt County, Nevada, to confirm if the reservoir is suitable for EGS development.

“We are grateful to the Department of Energy for funding these grants. We believe this is a clear indication from the federal government that expanding geothermal energy to new states is a national priority,” Jack Norbeck, CTO and co-founder of Fervo Energy, said in a news release. “We expect this funding to accelerate Fervo’s pipeline and advance the cutting edge of geothermal technologies.”

Fresh off a $180 million Series B, Quaise Energy also received $25 million in DOE funding through the initiative to support its Project Obsidian super hot geothermal plant in Central Oregon. The funding will go toward the analysis of the drilling, stimulation and flow results of the first two wells at the Project Obsidian site, which will help the company optimize its third well on site.

“This DOE support is a recognition of what we are building at Quaise and the progress we are making in the field, including the confirmation well currently being drilled at Project Obsidian,” Carlos Araque, CEO and president of Quaise, said in a release. “Our ambition has always been to make superhot geothermal a commercial reality, and Project Obsidian is where we first deliver on that promise.”

XGS Energy, which recently relocated its headquarters from Palo Alto, California, to Houston, was also selected for an exploration drilling project. The company will drill a deep vertical appraisal well in Socorro County, New Mexico, to determine if the site is a viable source of geothermal energy. XGS had not disclosed a funding estimate at press time.

The full value of the proposed DOE funding is subject to completion of award negotiations, according to Quaise.

Data from these projects will be shared through DOE’s Geothermal Data Repository (GDR), providing valuable information to researchers and stakeholders in the geothermal sector.

“This is an excellent example of how public and private entities can partner together to scale critical energy technologies,” Tim Latimer, CEO and co-founder of Fervo, added in a release. “With this funding, the Department of Energy is making important investments to help Americans across the country gain access to clean, affordable geothermal energy.”

Other geothermal companies and institutions from around the country will complete the 17 remaining projects. They include:

  • Denver-based 400C Energy Inc.
  • Salt Lake City-based AlterG Resources
  • Denver-based DAVINCI EP LLC
  • Anchorage-based GeoAlaska LLC
  • Oklahoma City-based GreenFire Energy Inc.
  • Virginia-based Hexagon Energy LLC
  • Virginia-based INTEK Inc.
  • Chicago-based Invenergy Geothermal Development LLC
  • Massachusetts-based LiPower Geothermal LLC
  • Fort Worth-based Oriah Geothermal LLC
  • Reno-based Raser Power Systems LLC
  • Santa Fe-based San Ildefonso Services LLC
  • Salt Lake City-based The University of Utah
  • Reno-based TLS Geothermics Corp.
  • Salt Lake City-based Zanskar Geothermal and Minerals

Read more about the full list of projects here.

CenterPoint gets $50M DOE grant to improve Houston power grid

grid grant

A $50 million federal grant will help Houston-based CenterPoint Energy strengthen Houston’s power grid.

The U.S. Department of Energy (DOE) grant will support power substation upgrades in the Houston area.

“Our mission is to build the most resilient coastal grid in the nation for the 2.9 million customers we proudly serve in the greater Houston area … [The grant] will directly fund industry-leading technology improvements that are expected to strengthen resiliency, reliability, and meet the growing energy needs of our region,” Jason Ryan, CenterPoint Energy’s executive vice president for regulatory services and government affairs, said in a release.

CenterPoint says the project will make it one of the first U.S. utilities to install Siemens Energy’s grid-stabilizing technology.

The project will create more than 500 construction and installation jobs, CenterPoint says.

“Generations of CenterPoint customers and families in the region will benefit from the advanced technology this grant is funding,” said Kathleen Jackson, a member of the Public Utility Commission of Texas. “And any time companies make improvements like this to their systems, the long-term impact is making the entire grid stronger for Texans.”

The $176.7 million substation project is part of CenterPoint’s Greater Houston Resiliency Initiative, which launched in 2024.

So far, the initiative has:

  • Installed nearly 82,400 storm-resilient poles and equipment
  • Trimmed and cleared more than 13,700 miles of trees and vegetation near power lines
  • Added nearly 820 grid automation and intelligence devices
  • Put more than 880 miles of power lines underground

The initiative kicked off three years after Winter Storm Uri. CenterPoint received harsh criticism for what customers complained was the utility’s slow response to the 2021 storm. Uri caused a massive power outage and at least 246 deaths across Texas.

CenterPoint blamed the Electric Reliability Council of Texas (ERCOT), which operates the power grid for most Texans, for not supplying the utility with enough electricity during and after the storm.

EnergyTech Cypher names 7 startup winners from Pilotathon pitch event

startup spotlight

Houston Energy and Climate Week was full of fast-paced pitches and inspiring technology, showcased during some of the week's signature events.

EnergyTech Cypher's annual Piloathon and Startup Showcase was one of the places to be, bringing together 16 pilot-ready startups to present their best seven-minute pitches before investors, plus 52 companies that demonstrated their technologies on the showcase floor.

"This year's cohort raised the bar," Nada Ahmed, co-founder of EnergyTech Cypher, shared in a news release. "Working with these founders through the pitch preparation process, we saw firsthand the depth of technology and commercial readiness they brought to the stage. Three ties in four categories says it all."

Seven startups took home top honors in various categories, all under this year's theme of "The NEW Energy Industrial Revolution," with three categories ending in a tie. Judges included leaders from Baker Tilly, NRG Energy, Shell, Aramco Ventures, Baker Hughes, Avatar Innovations, Kanin Energy, NoviDigiTech, aiCTO Services, and the FIFA World Cup Houston Committee.

Here's who won in their respective categories:

Future of Industrial Work: Houston-based BigMachine AI, an AI engineer for industrial projects, and Oslo, Norway-based OTee, an automation machinery manufacturer. Otee was also named one of the 10 most-promising startups at the Rice Alliance Energy Tech Venture Forum during HECW.

Industrial Decarbonization: Berkeley-based Oleo, which is developing a biomanufacturing platform to transform biomass waste into carbon-negative, cost-competitive oil feedstocks for advanced fuels

Grid Infrastructure and Distributed Energy: Edinburgh-based Mocean Energy, which works to deliver renewable ocean energy to power offshore industry, and Tulsa-based RyuGen Energy Solutions Inc., which works to turn underused commercial power into distributed AI infrastructure

Critical Minerals and Resource Security: Houston-based Resollant, which is working to produce battery-grade graphite and ultra-low-cost hydrogen, and Berkeley-based Sunchem, which provides precision separation of critical metals from sources including e-waste, evaporator scrap, solar panels, and mining ores and concentrates.

Last year, the Pilotathon named eight winners from the competition, which focused on the theme of "Energy Access and Resilience." See the winners here.

EnergyTech Cypher rebranded from EnergyTech Nexus earlier this year. The energy transition hub also launched Cephyron, EnergyTech Cypher's new investor relationship management platform, built specifically for energy and climatech founders.