Houston organization rolls out new accelerator to support companies tackling 'pressing global challenges'

CALLING FOR APPLICANTS

Calling all biotechnology startups focusing on sustainable feedstocks, commercially viable yields, and purpose fit microbes. Photo via Getty Images

A Houston organization — freshly funded by a $700,000 U.S. Economic Development Administration’s “Build to Scale” grant — is seeking its first accelerator cohort of industrial biology startups.

Founded by Houston-based First Bight Ventures, the BioWell has launched a virtual accelerator program that will provide programming, networking, mentorship, and financial resources to its inaugural cohort of 10 bioindustrial startups. The selected companies will also have access to specialized pilot bioproduction infrastructure throughout the nine-month program.

“BioWell equips startups with more than just capital. We provide a foundation for breakthrough innovations by combining access to cutting-edge bioproduction facilities with expertise that nurtures scalability. This comprehensive support is crucial for transforming pioneering ideas into market-ready solutions that can address pressing global challenges,” Carlos Estrada, head of venture acceleration at BioWell, says in a news release.

Applications for the program are open until May 15, and the cohort will be announced in June. Specifically, BioWell is seeking seed or pre-seed startup applicants that have a technology readiness level of 3 to 5, focusing on areas including low-cost and sustainable feedstocks, commercially viable yields, and purpose fit microbes.

“During our selection process, we'll prioritize startups that demonstrate a commitment to not only hitting milestones but also to building sustainable revenue streams for long-term survival. This phase necessitates keen awareness of market dynamics, customer demands, and sound financial management,” adds First Bight Ventures and BioWell Founder Veronica Wu.

In December, BioWell secured $741,925 of the $53 million doled out as a part of the "Build to Scale" Grant program that the U.S. Economic Development Administration, a division of the U.S. Department of Commerce, has established. First Bight was one of 60 organizations to receive funding.

Ex-Apple exec Wu founded First Bight Ventures in Houston in 2022 after relocating from Silicon Valley and seeing the region's potential for biotech.

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This article originally ran on InnovationMap.

First Bight Venture's BioWell has received a $741,925 grant to continue supporting bioindustrial startups. Photo via Getty Images

Houston nonprofit accelerator receives grant funding to advance bioindustrial startups

the biowell

A Houston-based nonprofit accelerator that works with early-stage synthetic biology startups has secured nearly $750,000 to support its mission.

First Bight Ventures' accelerator, BioWell, secured $741,925 of the $53 million doled out as a part of the "Build to Scale" Grant program that the U.S. Economic Development Administration, a division of the U.S. Department of Commerce, has established. First Bight was one of 60 organizations to receive funding.

The funding will support the BioWell's mission to establish a "vibrant bioeconomy" by helping startups scale and commercialize "through access to a unique combination of pilot bioproduction infrastructure," according to a news release from First Bight.

"Startups at BioWell will gain access to a robust ecosystem, expertise, mentorship, and financial resources essential for successfully commercializing their bio-industrial innovations," BioWell Executive Director Paul Palmer says in the release.

The BioWell is still working toward establishing a physical space and has worked out of the East End Maker Hub in the meantime. The organization has partnered with Urban Partnerships Community Development Corporation, or UP CDC, which led the application process on this federal grant.

"BioWell chose to partner with UP CDC for the EDA grant, to continue the successful model that UP CDC has created at the East End Maker Hub for advanced manufacturing. UP CDC looks forward to continuing our partnership with BioWell in the UP CDC's BioCity project that will position Houston at the forefront of bio-manufacturing," UP CDC's CEO Patrick Ezzell says in the release.

First Bight Ventures Founder Veronica Wu established the BioWell to target high-potential startups, which usually have to overcome lack of funding challenges early on.

"Often times, early-stage startups gain momentum and hit important milestones, but ultimately find themselves heading toward the 'Valley of Death,' where progress is made on their enterprise, but no sufficient revenue is generated for the company's stability and longevity," Wu says in the release. "This 'Build to Scale' program's support will help offset these inevitable challenges in our bio-industrial space."

She shares more about her mission for First Bight Ventures on the Houston Innovators Podcast. Listen to the interview from March below.

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This article originally ran on InnovationMap.

Houston VC invests in early stage California biodegradable plastics startup

seed funding

Houston-based venture capital firm First Bight Ventures led a $5 million seed round for Encinitas, California-based startup Algenesis, a developer of biodegradable plastics.

Algenesis bills its patented Soleic technology as the world’s first renewable, high-performance, fully biodegradable, and backyard-compostable polyurethane made from plants and algae. Each year, 25 million tons of hard-to-recycle polyurethane are produced for the footwear, medical, and textile industries. Polyurethane, typically made from petroleum, usually ends up as landfill waste or environmental microplastics.

Algenesis says Soleic can biodegrade in compost within a matter of months and does not contain harmful PFAS chemicals found in other plastics.

Algenesis says the new funding will enable it to expand beyond soft-foam applications, such as midsoles and insoles for footwear, and into injection-molded products such as smartphone cases along with waterproof textiles.

Aside from First Bight Ventures, investors in the seed round are Singapore-based Circulate Capital, India-based MIH Capital, Chesapeake, Virginia-based Diamond Sports Group, and France-based Rhinoshield.

The investment comes on the heels of a $5 million grant Algenesis received from the U.S. Department of Energy to scale up production of biochemicals.

“To save our planet and ourselves, we must move away from petroleum-based plastics and toward bio-based alternatives. Algenesis is clearly at the forefront of making this possible,” says Veronica Wu, founder of First Bight Ventures.

First Bight, which launched in 2022, invests in early-stage startups working on synthetic biology.

“First Bight is investing to bring the best and the brightest — and most promising — synthetic biology startups from around the country to Houston,” Wu said last year.

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Greentown Labs combines forces with MassChallenge to support more climate startups

strategic partnership

Climatetech incubator Greentown Labs has formed a strategic partnership with global zero-equity accelerator MassChallenge.

The two organizations have headquarters in the Boston area, while Greentown Labs is also co-located in Houston. MassChallenge has a hub in Dallas, as well as others in Israel, Switzerland and the United Kingdom.

The new partnership aims to strengthen the ecosystem for early-stage climatetech startups by providing more mentorship, support and a broader commercialization network for members, according to a news release.

Greentown Labs will share its expertise with the 23 startups in MassChallenge's first climate-specific accelerator, known as the MassChallenge Early Stage Climate program. Additionally, Greentown Labs members will benefit from MassChallenge's network of expert mentors, judges, entrepreneurs, partners, investors, philanthropists and others.

“There are so many synergies and shared values between MassChallenge and Greentown that launching a collaboration like this feels like a natural next step for our organizations as we strive to support as many early-stage climate founders as possible,” Georgina Campbell Flatter, Greentown Labs CEO, said in the news release. “We want to reduce the friction and barriers to market for these climate entrepreneurs and ultimately increase their opportunity for success—ecosystem collaboration is an essential part of solving these challenges together.”

Combined, Greentown and MassChallenge report that they have supported more than 4,500 founders and more than 1,000 climate startups. MassChallenge has awarded more than $18 million in equity-free grants to startups, which have gone on to raise over $15 billion, since it was founded in 2009. Greentown Labs has helped more than 575 startups raise more than $8.2 billion in funding since it launched in 2011.

Greentown recently added five startups to its Houston community and 14 other climatetech ventures to its Boston incubator. It also announced its third ACCEL cohort, which works to advance BIPOC-led startups in the climatetech space, earlier this year. Read more here.

$135M battery facility breaks ground in Houston and more energy news to know

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Editor's note: We're looking back at the hottest EnergyCapitalHTX stories from the second half of May 2025. Our most-read stories from May 16-30 include large-scale battery storage developments, collaborations with major brands, and a scientific breakthrough.

$135 million Houston battery storage facility breaks ground

SMT Energy, CenterPoint and Irby Construction have broken ground on a 160-megawatt battery energy storage system in ERCOT's Houston zone. Photo via Getty Images

SMT Energy and CenterPoint Energy have partnered with utility infrastructure solutions provider Irby Construction Company to break ground on a 160 megawatt battery energy storage system (BESS) located in the Houston zone of the ERCOT market.

“We are proud to be underway and deliver this grid-strengthening project to Houston,” Kevin Midei, SVP of engineering, procurement and construction, at SMT Energy, said. Continue reading.

Houston researchers make breakthrough on electricity-generating bacteria

A team of Rice researchers, including Caroline Ajo-Franklin and Biki Bapi Kundu, has uncovered how certain bacteria breathe by generating electricity. Photo by Jeff Fitlow/Rice University.

New research from Rice University that merges biology with electrochemistry has uncovered new findings on how some bacteria generate electricity.

Led by Caroline Ajo-Franklin, a Rice professor of biosciences and the director of the Rice Synthetic Biology Institute, the team published its findings in the journal Cell in April. The report showed how some bacteria use compounds called naphthoquinones, rather than oxygen, to transfer electrons to external surfaces in a process known as extracellular respiration. In other words, the bacteria are exhale electricity as they breathe. Continue reading.

Ultra-fast EV charging bays coming to Waffle House locations in Texas and beyond

bp pulse plans to install a network of DC fast chargers at Waffle House locations in Texas, Georgia and Florida. Photo via Getty Images.

Scattered, smothered and ... charged? Starting next year, EV drivers can connect to ultra-fast charging stations at select Waffle House locations throughout Texas, courtesy of bp pulse.

The EV arm of British energy giant bp announced a strategic partnership with the all-day breakfast chain. The company aims to deploy a network of 400kW DC fast chargers and a mix of CCS and NACS connectors at Waffle House locations in Texas, Georgia, Florida, and other restaurants in the South.Continue reading.

Engie partners on major Texas, California battery storage portfolio

Engie and CBRE are partnering up. Photo via Getty Images

Houston’s Engie North America has partnered with New York-based CBRE Investment Management on a 2.4-gigawatt portfolio of battery storage assets in Texas and California.

The portfolio consists of 31 projects operating in the Electric Reliability Council of Texas (ERCOT) and California Independent System Operator (CAISO) territories. According to a company statement, the transaction represents one of Engie’s largest operating portfolio partnerships in the U.S. Continue reading.

Houston renewables developer and Google agree to second solar collaboration

Google will soon be able to pull from energyRe’s portfolio of more than 600 megawatts of new solar and solar storage projects in South Carolina. Photo via Pixabay

EnergyRe, a developer of large-scale renewable energy projects with headquarters in Houston and New York, has signed a renewable energy agreement that will allow Google to invest in and purchase renewable energy credits (RECs) from its projects under development in South Carolina.

Google will be able to pull from energyRe’s portfolio of more than 600 megawatts of new solar and solar storage projects in the state. Continue reading.

Houston cleantech accelerator names 12 startups to 2025 cohort

early-stage accelerator

The Rice Alliance Clean Energy Accelerator has named 12 early-stage startups to its latest cohort.

The hybrid program, which operates in a hybrid capacity based out of the Ion, runs for 10 weeks and provides energy transition startups with training focused on fundraising, pilots, partnerships and sale. It begins July 8 and will be led by executive director Kerri Smith and program director Matthew Peña with support from executives-in-residence Lynn Frostman, John Jeffers, David Horsup and Dev Motiram.

The accelerator will culminate with a demo day on Sept. 18 at the Rice Alliance Energy Tech Venture Forum during the Houston Energy and Climate Startup Week.

Members of this year's cohort come from the Houston area as well as across the U.S. and Canada.

Class 5 for the Rice Alliance Clean Energy Accelerator includes:

Aqua-Cell Energy, which builds industrial-scale overnight batteries to provide affordable solar power
Arculus, a company that provides multilayer internal coating for pipelines that lowers friction, extends pipeline life and enables carbon dioxide transport and hydrogen blending
AtmoSpark, a Houston-based sustainable cooling and freshwater company that provides an electric field-driven air separation system that reduces dehumidification energy costs for data centers and industrial facilities
AtoMe, which delivers durable metallic composites to energy and aerospace companies using an eco-friendly dry blade method that eliminates harmful chemicals
ConceptLoop, a company that converts plastic waste into eco-friendly, low-carbon aggregate
Fathom Storage, which provides a more solidly embedded and steel-efficient anchoring solution for offshore service providers, wind energy developers and research institutes
GeoKiln, a Houston-based company that addresses issues of subsurface hydrogen extraction by applying proven oil and gas techniques to accelerate natural hydrogen reactions, enabling hydrogen production
Innowind Energy Solutions, a company that provides nonintrusive, active flow control devices to boost energy production and extend turbine lifespan
Lukera Energy, which transforms waste methane into high-value methanol using a breakthrough nanobubble technology
Metal Light Inc., which has developed a scalable, cost-effective Metal-Air generator to replace diesel generators
Moonshot Hydrogen, a company that converts food and agricultural waste into clean hydrogen and bioethanol
Resollant, a Woodlands-based company that delivers compact, zero-emission hydrogen and carbon reactors to refineries, petrochemical plants, steel and cement manufacturers and fuel producers

The Rice Alliance Clean Energy Accelerator has supported 55 ventures since it was founded in 2021, collectively raising over $250 million in funding, according to the university. See last year's cohort here.

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