Houston organization rolls out new accelerator to support companies tackling 'pressing global challenges'

CALLING FOR APPLICANTS

Calling all biotechnology startups focusing on sustainable feedstocks, commercially viable yields, and purpose fit microbes. Photo via Getty Images

A Houston organization — freshly funded by a $700,000 U.S. Economic Development Administration’s “Build to Scale” grant — is seeking its first accelerator cohort of industrial biology startups.

Founded by Houston-based First Bight Ventures, the BioWell has launched a virtual accelerator program that will provide programming, networking, mentorship, and financial resources to its inaugural cohort of 10 bioindustrial startups. The selected companies will also have access to specialized pilot bioproduction infrastructure throughout the nine-month program.

“BioWell equips startups with more than just capital. We provide a foundation for breakthrough innovations by combining access to cutting-edge bioproduction facilities with expertise that nurtures scalability. This comprehensive support is crucial for transforming pioneering ideas into market-ready solutions that can address pressing global challenges,” Carlos Estrada, head of venture acceleration at BioWell, says in a news release.

Applications for the program are open until May 15, and the cohort will be announced in June. Specifically, BioWell is seeking seed or pre-seed startup applicants that have a technology readiness level of 3 to 5, focusing on areas including low-cost and sustainable feedstocks, commercially viable yields, and purpose fit microbes.

“During our selection process, we'll prioritize startups that demonstrate a commitment to not only hitting milestones but also to building sustainable revenue streams for long-term survival. This phase necessitates keen awareness of market dynamics, customer demands, and sound financial management,” adds First Bight Ventures and BioWell Founder Veronica Wu.

In December, BioWell secured $741,925 of the $53 million doled out as a part of the "Build to Scale" Grant program that the U.S. Economic Development Administration, a division of the U.S. Department of Commerce, has established. First Bight was one of 60 organizations to receive funding.

Ex-Apple exec Wu founded First Bight Ventures in Houston in 2022 after relocating from Silicon Valley and seeing the region's potential for biotech.

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This article originally ran on InnovationMap.

First Bight Venture's BioWell has received a $741,925 grant to continue supporting bioindustrial startups. Photo via Getty Images

Houston nonprofit accelerator receives grant funding to advance bioindustrial startups

the biowell

A Houston-based nonprofit accelerator that works with early-stage synthetic biology startups has secured nearly $750,000 to support its mission.

First Bight Ventures' accelerator, BioWell, secured $741,925 of the $53 million doled out as a part of the "Build to Scale" Grant program that the U.S. Economic Development Administration, a division of the U.S. Department of Commerce, has established. First Bight was one of 60 organizations to receive funding.

The funding will support the BioWell's mission to establish a "vibrant bioeconomy" by helping startups scale and commercialize "through access to a unique combination of pilot bioproduction infrastructure," according to a news release from First Bight.

"Startups at BioWell will gain access to a robust ecosystem, expertise, mentorship, and financial resources essential for successfully commercializing their bio-industrial innovations," BioWell Executive Director Paul Palmer says in the release.

The BioWell is still working toward establishing a physical space and has worked out of the East End Maker Hub in the meantime. The organization has partnered with Urban Partnerships Community Development Corporation, or UP CDC, which led the application process on this federal grant.

"BioWell chose to partner with UP CDC for the EDA grant, to continue the successful model that UP CDC has created at the East End Maker Hub for advanced manufacturing. UP CDC looks forward to continuing our partnership with BioWell in the UP CDC's BioCity project that will position Houston at the forefront of bio-manufacturing," UP CDC's CEO Patrick Ezzell says in the release.

First Bight Ventures Founder Veronica Wu established the BioWell to target high-potential startups, which usually have to overcome lack of funding challenges early on.

"Often times, early-stage startups gain momentum and hit important milestones, but ultimately find themselves heading toward the 'Valley of Death,' where progress is made on their enterprise, but no sufficient revenue is generated for the company's stability and longevity," Wu says in the release. "This 'Build to Scale' program's support will help offset these inevitable challenges in our bio-industrial space."

She shares more about her mission for First Bight Ventures on the Houston Innovators Podcast. Listen to the interview from March below.

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This article originally ran on InnovationMap.

Houston VC invests in early stage California biodegradable plastics startup

seed funding

Houston-based venture capital firm First Bight Ventures led a $5 million seed round for Encinitas, California-based startup Algenesis, a developer of biodegradable plastics.

Algenesis bills its patented Soleic technology as the world’s first renewable, high-performance, fully biodegradable, and backyard-compostable polyurethane made from plants and algae. Each year, 25 million tons of hard-to-recycle polyurethane are produced for the footwear, medical, and textile industries. Polyurethane, typically made from petroleum, usually ends up as landfill waste or environmental microplastics.

Algenesis says Soleic can biodegrade in compost within a matter of months and does not contain harmful PFAS chemicals found in other plastics.

Algenesis says the new funding will enable it to expand beyond soft-foam applications, such as midsoles and insoles for footwear, and into injection-molded products such as smartphone cases along with waterproof textiles.

Aside from First Bight Ventures, investors in the seed round are Singapore-based Circulate Capital, India-based MIH Capital, Chesapeake, Virginia-based Diamond Sports Group, and France-based Rhinoshield.

The investment comes on the heels of a $5 million grant Algenesis received from the U.S. Department of Energy to scale up production of biochemicals.

“To save our planet and ourselves, we must move away from petroleum-based plastics and toward bio-based alternatives. Algenesis is clearly at the forefront of making this possible,” says Veronica Wu, founder of First Bight Ventures.

First Bight, which launched in 2022, invests in early-stage startups working on synthetic biology.

“First Bight is investing to bring the best and the brightest — and most promising — synthetic biology startups from around the country to Houston,” Wu said last year.

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Rice, DOE launch new Eastern Mediterranean Energy Center

Energy Diplomacy

Representatives from three countries visited the Rice University Baker Institute for Public Policy this month to establish the Eastern Mediterranean Energy Center, a new partnership promoting energy advancement in the region.

On June 11, Baker played host to delegations from Cyprus, Greece and Israel that included Michael Damianos, Minister of Energy, Commerce and Industry of the Republic of Cyprus; Stavros Papastavrou, Minister of Environment and Energy for Greece; and Yechiel Leiter, Israeli Ambassador to the United States. U.S. Secretary of Energy Chris Wright and Rice University President Reginald DesRoches were also present to sign a declaration of intent (DOI) that officially formed the partnership first envisioned in the Eastern Mediterranean Security and Energy Partnership Act of 2019.

“This is a dynamic field,” David Satterfield, director of the Baker Institute and former U.S. ambassador to Turkey and Lebanon, said in a news release from Rice. “The East Med has enormous further potential, not just for development, for coordination of development. It is a positive thing for energy, it's a positive thing for industry, for all of the three states represented here today. It's good for the region in a geopolitical sense as well. It provides a stabilization based upon the pragmatic and integrated development and distribution of energy resources, and that is a very good thing indeed.”

The new pact will focus on improving grid stability in the region, as well as on developing U.S. liquefied natural gas (LNG) infrastructure and new technologies.

Another goal of the Eastern Mediterranean Energy Center is suppressing conflict in the region. When the Eastern Mediterranean Security and Energy Partnership Act was signed by President Joe Biden in 2019, it lifted the prohibition on arms sales to the Republic of Cyprus, authorized foreign military financing for Greece and increased intelligence gathering on Russian interests in the Mediterranean.

“We need to use commerce to suppress and surpass conflict – that is the way to bring nations together in geopolitical tensions between countries,” Wright said in the release. “You think of it as zero-sum, there's a winner and a loser, and both sides want to be the winner. Ultimately, one side will be the winner, one side will be the loser. Maybe more objectively, both sides lose, but one loses more than the other. In commerce, it's entirely different, and commerce is voluntary exchange. It only happens when there's winners on both sides. So, when you build, you develop energy and you build energy distribution infrastructure, you bring countries, you bring people together. The three founding nations here and their leadership are all friends of mine and passionate in this mission. They not only want to develop energy to bring better opportunities to their people, but they wanted to bring those three nations together, and all of their neighbors as well, and use commerce to suppress and surpass conflict. These are generational investments.”

6 Houston companies earn recognition on Time’s global greentech list 2026

green giants

Six Houston-area businesses appear on Time magazine’s 2026 list of the world’s top greentech companies, with a high-flying name leading the pack.

The highest-ranked local company is Houston-based geothermal power producer Fervo Energy, which claims the No. 4 spot—up from No. 14 last year.

In May, Fervo raised nearly $1.9 billion in its IPO, making it the biggest-ever IPO in the clean energy sector. The company’s valuation now exceeds $10 billion.

Founded in 2017, Fervo borrows methods from the oil and gas sector to drill wells that go down vertically into hot rock before turning horizontal, letting water circulate through them and produce electricity from the heat it absorbs. Cape Station in Utah, the company's first utility-scale project, is set to start delivering power to the grid later this year, with capacity expected to grow to 100 megawatts by 2027.

Co-founder and CEO Tim Latimer tells Fast Company, which named him a 2026 Visionary of the Year, that he launched his career as a drilling engineer for fossil fuels, “but quickly became obsessed with this idea that the drilling techniques we were using would actually be transformative for the world of geothermal as well.”

Fast Company notes the geothermal power generated by Cape Station will be available 24/7, unlike wind and solar power.

“When you start adding something to the grid mix that’s affordable and works around the clock,” Latimer says, “that’s going to be a huge asset to meeting our country’s energy needs.”

Time teamed up with data provider Statista to compile the second annual ranking of the 250 top greentech companies in the world. Companies on the list either develop or provide green technology, products, or services that help ease or reverse the environmental impacts of human activity.

Statista gathered and analyzed data from more than 8,300 companies to create the list, and they were scored in three categories: positive environmental impact, innovation, and financial strength. Fervo earned a score of 94.63 out of 100.

Joining Fervo on this year’s list are:

Houston-based Quaise Energy (No. 78), which specializes in terawatt-scale geothermal power
The Woodlands-based Plus Power (No. 112), which develops, owns and operates battery storage projects
Houston-based Utility Global (No. 167), which develops decarbonization technology
Houston-based 1PointFive (No. 217), an Occidental Petroleum subsidiary that offers large-scale carbon removal and storage.
Houston-based Sage Geosystems (No. 250), which produces commercial-scale geothermal power

Earlier this year, six Houston-area companies landed on Time's list of top greentech companies in America: Fervo (No. 1), Quaise Energy (No. 49), Plus Power (No. 71), Utility Global (No. 98), Solugen (No. 199) and Noodoe (No. 215).

Houston-based Syzygy lands global customer for first commercial SAF plant

clean fuel deal

Houston-based Syzygy Plasmonics has secured a major future customer for its sustainable aviation fuel.

Syzygy announced this week that it has entered into a capacity reservation agreement with World Fuel Services, a global fuel distribution and logistics company.

Through the deal, World Fuel has reserved a portion of Syzygy's SAF production for future plants slated for Central and South America. The clean fuel will be produced at Syzygy’s NovaSAF-1 facility in Uruguay, which is moving toward construction.

The NovaSAF-1 will be the world's first electrified facility to convert biogas into sustainable aviation fuel (SAF). The facility is expected to produce over 350,000 gallons of SAF annually, which would be considered “a breakthrough in cost-effective, scalable clean fuel,” according to Syzygy.

The facility is expected to produce SAF with at least an 80 percent reduction in carbon intensity compared to Jet A fuel and make its first deliveries in 2028.

"Following NovaSAF-1, this agreement reflects continued interest in scalable pathways for producing SAF from biogas," Trevor Best, CEO of Syzygy Plasmonics, said in a news release. "Our NovaSAF platform is designed to deliver cost-competitive fuel while supporting the aviation sector's evolving regulatory and sustainability requirements."

Syzygy will make a portion of future production capacity available to World Fuel from its planned facilities, subject to the development and completion of those projects, according to the deal.

"We continue to evaluate supply opportunities that support increased access to lower carbon fuels in aviation, in line with emerging regulatory requirements and customer demand," Michael Ranger, senior vice president of supply EMEAA at World Fuel, added in the release. "Arrangements such as this are part of our ongoing efforts across the supply chain.”

Syzygy also secured an offtake agreement with Singapore-based commodity company Trafigura from NovaSAF-1 earlier this year.

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