new findings

Houston researchers make breakthrough on electricity-generating bacteria

A team of Rice researchers, including Caroline Ajo-Franklin and Biki Bapi Kundu, has uncovered how certain bacteria breathe by generating electricity. Photo by Jeff Fitlow/Rice University.

New research from Rice University that merges biology with electrochemistry has uncovered new findings on how some bacteria generate electricity.

Led by Caroline Ajo-Franklin, a Rice professor of biosciences and the director of the Rice Synthetic Biology Institute, the team published its findings in the journal Cell in April. The report showed how some bacteria use compounds called naphthoquinones, rather than oxygen, to transfer electrons to external surfaces in a process known as extracellular respiration. In other words, the bacteria are exhale electricity as they breathe.

This process has been observed by scientists for years, but the Rice team's deeper understanding of its mechanism is a major breakthrough, with implications for the clean energy and industrial biotechnology sectors, according to the university.

“Our research not only solves a long-standing scientific mystery, but it also points to a new and potentially widespread survival strategy in nature,” Ajo-Franklin, said in a news release.

The Rice team worked with the University of California, San Diego's Palsson lab to simulate bacterial growth using advanced computer modeling. The simulations modeled oxygen-deprived environments that were rich in conductive surfaces, and found that bacteria could sustain themselves without oxygen. Next, they confirmed that the bacteria continued to grow and generate electricity when placed on conductive materials.

The team reports that the findings "lay the groundwork for future technologies that harness the unique capabilities" of these bacteria with "far-reaching practical implications." The team says the findings could lead to significant improvements in wastewater treatment and biomanufacturing. They could also allow for better bioelectronic sensors in oxygen-deprived environments, including deep-sea vents, the human gut and in deep space.

“Our work lays the foundation for harnessing carbon dioxide through renewable electricity, where bacteria function similarly to plants with sunlight in photosynthesis,” Ajo-Franklin added in the release. “It opens the door to building smarter, more sustainable technologies with biology at the core.”

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A View From HETI

Molecule has made a strategic acquisition following the closing of its Series B last summer. Photo via Getty Images

Houston-based energy trading risk management (ETRM) software company Molecule has announced the acquisition of Dallas-based Trilogy Energy Solutions.

Molecule CEO Patrick Smith called the deal a "defining moment" for the company, as it allows Molecule's platform to expand to include physical gas operations.

“For years, this industry has drawn the ETRM box too small, creating inefficient silos by treating trading and physical operations as separate budgets and separate problems, when the real cost lives in the handoffs between them," Smith said in a news release. "Trilogy’s domain expertise in physical gas operations closes that gap. Together, we can give producers, midstream operators, and trading desks something the market has been asking for: a single, integrated view from wellhead to trading desk, without the manual reconciliation, spreadsheet workarounds, and legacy handoffs that slow the industry down.”

Trilogy, founded in 2014, is a provider of cloud-based software for the day-to-day logistics of physical natural gas operations. The platform allows users—including producers, marketers, midstream companies, pipeline operators and others—to manage activities such as pipeline nominations, gas gathering operations and more. Thus far, Molecule's platform has focused on energy trading and managing financial and commercial activities.

Through the acquisition, the combined company will now offer a full-stack enabled ETRM and energy operating system. Users of both platforms can expect continuity of service, according to the companies.

“Molecule has always been about meeting trading teams where they actually work, focused on being fast, accurate, and deeply integrated into their day-to-day workflow,” Sameer Soleja, founder and president of Molecule, added in the release. “Bringing Trilogy into the Molecule family extends that mission from the trading desk into the physical operations of the gas business. The two platforms complement each other exceedingly well, and the combined product will be able to offer all-in-one capabilities that lead the ETRM market, both in its tech-forward nature, and in its depth.”

Molecule expects the combined platform to help users reduce manual month-end close work, cut costs, and improve data accuracy and decision-making.

Trilogy's Chief Product Officer Jeremy Frye will join the Molecule team, along with others from Trilogy.

“Trilogy has spent decades building the trust of companies across the physical natural gas industry by delivering software that stands up to the demands of physical gas operations... It’s a rare combination that brings the best of both worlds, and I’m energized about what our teams will build together,” Frye added in the release.

California-based Sundance Growth, an existing investor in Molecule, supported the acquisition. The software growth equity firm raised a $125 million debut fund in 2025 and focuses on B2B SaaS companies.

Sundance led Molecule's Series B round, which closed last summer for an undisclosed amount. At the time, Soleja said the funding would allow Molecule to "double down on product innovation, grow our team, and reach even more markets."

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