A team of Rice researchers, including Caroline Ajo-Franklin and Biki Bapi Kundu, has uncovered how certain bacteria breathe by generating electricity. Photo by Jeff Fitlow/Rice University.
New research from Rice University that merges biology with electrochemistry has uncovered new findings on how some bacteria generate electricity.
Led by Caroline Ajo-Franklin, a Rice professor of biosciences and the director of the Rice Synthetic Biology Institute, the team published its findings in the journal Cell in April. The report showed how some bacteria use compounds called naphthoquinones, rather than oxygen, to transfer electrons to external surfaces in a process known as extracellular respiration. In other words, the bacteria are exhale electricity as they breathe.
This process has been observed by scientists for years, but the Rice team's deeper understanding of its mechanism is a major breakthrough, with implications for the clean energy and industrial biotechnology sectors, according to the university.
“Our research not only solves a long-standing scientific mystery, but it also points to a new and potentially widespread survival strategy in nature,” Ajo-Franklin, said in a news release.
The Rice team worked with the University of California, San Diego's Palsson lab to simulate bacterial growth using advanced computer modeling. The simulations modeled oxygen-deprived environments that were rich in conductive surfaces, and found that bacteria could sustain themselves without oxygen. Next, they confirmed that the bacteria continued to grow and generate electricity when placed on conductive materials.
The team reports that the findings "lay the groundwork for future technologies that harness the unique capabilities" of these bacteria with "far-reaching practical implications." The team says the findings could lead to significant improvements in wastewater treatment and biomanufacturing. They could also allow for better bioelectronic sensors in oxygen-deprived environments, including deep-sea vents, the human gut and in deep space.
“Our work lays the foundation for harnessing carbon dioxide through renewable electricity, where bacteria function similarly to plants with sunlight in photosynthesis,” Ajo-Franklin added in the release. “It opens the door to building smarter, more sustainable technologies with biology at the core.”
Cleantech startup Cemvita has set up a pilot plant in its hometown of Houston to develop technology for converting carbon emissions as feedstock to make products like fertilizer, plastics, methane, and fuel.
The opening of the pilot plant marks the debut of Cemvita’s eCO2 business as a wholly owned subsidiary. The term eCO2 refers to equivalent carbon dioxide, or a way to measure a combination of greenhouse gases such as carbon dioxide and methane.
With a capacity of more than 14,000 gallons, the plant is producing eCO2 oil, an alternative to soybean oil. The company already is shipping samples of eCO2 products to customers, including renewable-fuel companies and plastics manufacturers.
“Traditional biofuels, including renewable diesel and sustainable aviation fuel, have relied on oils derived from crops, such as soybean and corn, as well as recycled vegetable oils,” Cemvita says. “As demand grows for petroleum-free alternatives, feedstock is in short supply and must compete with food markets. Crops of soybeans, sugar, and corn use huge swaths of land, and the raw materials require extensive refining — two factors that impede the processes from being sustainable.”
By contrast, eCO2 plants like Cemvita’s can supply feedstock production with minimal land and electricity requirements, and without relying on hydrogen or sunlight, the company says. Furthermore, the output of eCO2 plants is designed to carbon-negative, not just carbon-neutral.
Cemvita’s eCO2 biomanufacturing platform uses engineered microbes that absorb and convert carbon dioxide into feedstocks and finished products.
“The energy transition requires completely new, cost-effective approaches for heavy industry,” Charlie Nelson, chief operating officer of Cemvita, says in a news release. “We built this next-generation pilot plant in response to strong demand from … partners who are actively seeking sustainable solutions to the … feedstock shortage.”
Brother-and-sister team Moji and Tara Karimi founded Cemvita in 2017.
Investors in Cemvita include Oxy Low Carbon Ventures, an investment arm of Houston-based Occidental Petroleum, as well as BHP Group, Mitsubishi, and United Airlines Ventures.
Oxy Low Carbon Ventures and United Airlines Ventures are financing Cemvita’s work on sustainable jet fuel. United Airlines operates a hub at George Bush Intercontinental Airport Houston.
Three Houston companies claimed spots on LexisNexis's 10 Most Innovative Startups in Texas report, with two working in the geothermal energy space.
Sage Geosystems claimed the No. 3 spot on the list, and Fervo Energy followed closely behind at No. 5. Fintech unicorn HighRadius rounded out the list of Houston companies at No. 8.
LexisNexis Intellectual Property Solutions compiled the report. It was based on each company's Patent Asset Index, a proprietary metric from LexisNexis that identifies the strength and value of each company’s patent assets based on factors such as patent quality, geographic scope and size of the portfolio.
Houston tied with Austin, each with three companies represented on the list. Caris Life Sciences, a biotechnology company based in Dallas, claimed the top spot with a Patent Asset Index more than 5 times that of its next competitor, Apptronik, an Austin-based AI-powered humanoid robotics company.
“Texas has always been fertile ground for bold entrepreneurs, and these innovative startups carry that tradition forward with strong businesses based on outstanding patent assets,” Marco Richter, senior director of IP analytics and strategy for LexisNexis Intellectual Property Solutions, said in a release. “These companies have proven their innovation by creating the most valuable patent portfolios in a state that’s known for game-changing inventions and cutting-edge technologies.We are pleased to recognize Texas’ most innovative startups for turning their ideas into patented innovations and look forward to watching them scale, disrupt, and thrive on the foundation they’ve laid today.”
This year's list reflects a range in location and industry. Here's the full list of LexisNexis' 10 Most Innovative Startups in Texas, ranked by patent portfolios.
Fervo Energy fully contracted its flagship 500 MW geothermal development, Cape Station, this spring. Cape Station is currently one of the world’s largest enhanced geothermal systems (EGS) developments, and the station will begin to deliver electricity to the grid in 2026. The company was recently named North American Company of the Year by research and consulting firm Cleantech Group and came in at No. 6 on Time magazine and Statista’s list of America’s Top GreenTech Companies of 2025. It's now considered a unicorn, meaning its valuation as a private company has surpassed $1 billion.
Meanwhile, HighRadius announced earlier this year that it plans to release a fully autonomous finance platform for the "office of the CFO" by 2027. The company reached unicorn status in 2020.
The climate conversation is evolving — fast. It’s no longer just about emissions targets and net-zero commitments. It’s about capital, infrastructure, and execution at industrial scale.
That’s exactly where Yao Huang operates. A seasoned tech entrepreneur turned climate investor, Yao brings sharp clarity to one of the biggest challenges in climate innovation: how do we fund and scale technologies that remove carbon without relying on goodwill or government subsidies?
In this episode of the Energy Tech Startups Podcast, Yao sits down with hosts Jason Ethier and Nada Ahmed for a wide-ranging conversation that redefines how we think about decarbonization. From algae-based photobioreactors that capture CO₂ at the smokestack, to financing models that mirror real estate and infrastructure—not venture capital—Yao lays out a case for why the climate fight will be won or lost on spreadsheets, not slogans.
Her message is as bold as it is practical: this isn’t about saving the planet for the sake of it. It’s about building profitable, resilient systems that scale. And Houston, with its industrial base and project finance expertise, is exactly the place to do it.
The 40-Gigaton Challenge—and a Pandemic Pivot
Yao’s entry into climate wasn’t part of a long-term plan. It was sparked by a quiet moment during the pandemic—and a book.
Reading How to Avoid a Climate Disaster by Bill Gates, she came to two uncomfortable realizations:
The people in power don’t actually have this figured out, and
She would be alive to suffer the consequences.
That insight jolted her out of the traditional tech world and into climate action. She studied at Stanford, surrounded herself with mentors, and began diving into early-stage climate deals. But she quickly realized that most of the solutions she was seeing were still years away from commercialization.
So she narrowed her focus: no R&D moonshots, no science experiments—just deployable solutions that could scale now.
Carbon Optimum: Where Algae Meets Infrastructure
That’s how she found Carbon Optimum, a company using algae photobioreactors to remove CO₂ directly from industrial emissions. Their approach is both elegant and economic:
Install algae reactors next to major emitters like coal and cement plants.
Feed the algae with flue gas, allowing it to absorb CO₂ in a controlled system.
Harvest the algae and convert it into valuable commodities like bio-oils, fertilizer, and food ingredients.
It’s a nature-based solution, enhanced by engineering. One acre of tanks can capture emissions and generate profit—without subsidies.
“This is one of the few solutions I’ve seen that can scale profitably and quickly,” Yao says. “And we’re not inventing anything new—we’re just doing it better.”
The Real Problem? It’s Capital, Not Carbon
As an investor, Yao is blunt: most climate startups are misaligned with the capital markets.
They’re following a tech startup playbook—built for SaaS, not steel. But building climate infrastructure requires a completely different approach: project finance, blended capital, debt structures, carbon credit integration, and regulatory incentives.
“Climate tech is more like real estate or healthcare than software,” Yao explains. “You don’t raise six rounds of venture. You build a stack—grants, equity, debt, tax credits—and you structure your project like infrastructure.”
It’s not just theory. It’s exactly how Carbon Optimum is expanding—through partnerships, offtake agreements, and real-world deployments. And it’s why she believes many climate startups fail: they don’t speak the language of finance.
Houston’s Role in the Climate Capital Stack
For Yao, Houston isn’t just a backdrop—it’s a strategic asset.
The city’s deep bench of project finance professionals, commodity traders, lawyers, and infrastructure veterans makes it uniquely positioned to lead the deployment phase of climate solutions.
“We’ve been calling it the wrong thing,” she says. “This isn’t just about climate—it’s an energy transition. And Houston knows how to build energy infrastructure at scale.”
Still, she notes, the ecosystem needs to evolve. Less education, more execution. Fewer workshops, more closers.
“Houston could be the epicenter of this movement—if we activate the right people and get the right projects over the line.”
From Carbon Capture to Circular Economies
The potential applications of Carbon Optimum’s algae platform go beyond carbon capture. Because the output—algae biomass—can be converted into:
Renewable oil
High-efficiency fertilizers (critical in today’s geopolitically fragile supply chains)
Food ingredients rich in protein and nutrients
Even biochar, a highly stable form of carbon sequestration
It’s scalable, modular, and location-agnostic. In island nations, Yao notes, these systems can offer energy independence by turning waste CO₂ into local energy and fertilizer—without needing to import fuels or food.
“It’s not just emissions reduction. It’s economic sovereignty through circular systems.”
Doing, Not Just Talking
One of Yao’s key takeaways for founders? Don’t waste time. Climate startups don’t have the luxury of trial-and-error cycles stretched over years.
“Founders need to get real about what it takes to scale: talent, capital, storytelling, partnerships. If you’re not ready to do that, maybe you should be a CSO, not a CEO.”
She also points out that founders don’t need to hire everyone—they need to tap the right networks. And in cities like Houston, those networks exist—if you know how to motivate them.
“It takes a different kind of leadership. You’re not just raising money—you’re moving people.”
Why This Episode Matters
This conversation is for anyone who’s serious about scaling real solutions to the climate crisis. Whether you’re a founder navigating capital markets, an investor seeking return and impact, or a policymaker designing the frameworks — Yao Huang offers a grounded, urgent, and actionable perspective.
It’s not about hope. It’s about execution.
Listen to the full episode of the Energy Tech Startups Podcast with Yao Huang:
-- Hosted by Jason Ethier and Nada Ahmed, the Digital Wildcatters’ podcast, Energy Tech Startups, delves into Houston's pivotal role in the energy transition, spotlighting entrepreneurs and industry leaders shaping a low-carbon future.
Rice University chemistry professor László Kürti was named as a recipient of the 2025 Ross M. Brown Investigator Award from the California Institute of Technology’s Brown Institute for Basic Sciences.
Kürti is one of eight mid-career faculty members to receive up to $2 million over five years for their research in the physical sciences.
“I’m greatly honored,” Kürti said in a news release. “We will learn a tremendous amount in the next five years and gain a much clearer understanding of the challenges ahead.”
Kürti was selected for the research he’s been developing for six years on a molecule called tetrahedral N4, which studies show can release large amounts of energy on demand. The molecule can also decompose directly into nitrogen gas without producing carbon dioxide or water vapor. Kürti believes N4 can be used as a "new type of fuel for vehicles."
“Eventually, N4 and other stable, neutral polynitrogen cages could be used to power rockets, helping us reach the moon or Mars faster and with heavier payloads,” he added in this release.
The Brown Investigator Awards were founded by entrepreneur and Caltech alumnus Ross M. Brown and established by the Brown Science Foundation in 2020. The organization has recognized 21 scientists over the last five years.
“Midcareer faculty are at a time in their careers when they are poised and prepared to make profound contributions to their fields,” Brown said in the news release. “My continuing hope is that the resources provided by the Brown Investigator Awards will allow them to pursue riskier innovative ideas that extend beyond their existing research efforts and align with new or developing passions, especially during this time of funding uncertainty.”
