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Houston researchers harness dialysis for new wastewater treatment process

Rice University's Menachem Elimelech and Yuanmiaoliang “Selina” Chen published a study in Nature Water on mimicking dialysis from the medical field to treat wastewater. Photo by Gustavo Raskosky/Rice University

By employing medical field technology dialysis, researchers at Rice University and the Guangdong University of Technology in China uncovered a new way to treat high-salinity organic wastewater.

In the medical field, dialysis uses a machine called a dialyzer to filter waste and excess fluid from the blood. In a study published in Nature Water, Rice’s team found that mimicking dialysis can separate salts from organic substances with minimal dilution of the wastewater, addressing some of the limitations of previous methods.

The researchers say this has the potential to lower costs, recover valuable resources across a range of industrial sectors and reduce environmental impacts.

“Traditional methods often demand a lot of energy and require repeated dilutions,” Yuanmiaoliang “Selina” Chen, a co-first author and postdoctoral associate in Elimelech’s lab at Rice, said in a news release. “Dialysis eliminates many of these pain points, reducing water consumption and operational overheads.”

Various industries generate high-salinity organic wastewater, including petrochemical, pharmaceutical and textile manufacturing. The wastewater’s high salt and organic content can present challenges for existing treatment processes. Biological and advanced oxidation treatments become less effective with higher salinity levels. Thermal methods are considered “energy intensive” and susceptible to corrosion.

Ultimately, the researchers found that dialysis effectively removed salt from water without requiring large amounts of fresh water. This process allows salts to move into the dialysate stream while keeping most organic compounds in the original solution. Because dialysis relies on diffusion instead of pressure, salts and organics cross the membrane at different speeds, making the separation method more efficient.

“Dialysis was astonishingly effective in separating the salts from the organics in our trials,” Menachem Elimelech, a corresponding author on the study and professor of civil and environmental engineering and chemical and biomolecular engineering at Rice, said in a news release. “It’s an exciting discovery with the potential to redefine how we handle some of our most intractable wastewater challenges.”

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A View From HETI

Rice University's László Kürti has been researching a molecule known as N4 that releases large amounts of energy. Photo by Jeff Fitlow/ Courtesy Rice University.

Rice University chemistry professor László Kürti was named as a recipient of the 2025 Ross M. Brown Investigator Award from the California Institute of Technology’s Brown Institute for Basic Sciences.

Kürti is one of eight mid-career faculty members to receive up to $2 million over five years for their research in the physical sciences.

“I’m greatly honored,” Kürti said in a news release. “We will learn a tremendous amount in the next five years and gain a much clearer understanding of the challenges ahead.”

Kürti was selected for the research he’s been developing for six years on a molecule called tetrahedral N4, which studies show can release large amounts of energy on demand. The molecule can also decompose directly into nitrogen gas without producing carbon dioxide or water vapor. Kürti believes N4 can be used as a "new type of fuel for vehicles."

“Eventually, N4 and other stable, neutral polynitrogen cages could be used to power rockets, helping us reach the moon or Mars faster and with heavier payloads,” he added in this release.

The Brown Investigator Awards were founded by entrepreneur and Caltech alumnus Ross M. Brown and established by the Brown Science Foundation in 2020. The organization has recognized 21 scientists over the last five years.

“Midcareer faculty are at a time in their careers when they are poised and prepared to make profound contributions to their fields,” Brown said in the news release. “My continuing hope is that the resources provided by the Brown Investigator Awards will allow them to pursue riskier innovative ideas that extend beyond their existing research efforts and align with new or developing passions, especially during this time of funding uncertainty.”

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