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Houston biotech co. sees unexpected production growth on sustainable oil

milestone met

Thanks to technology advancements, Cemvita is now capable of generating 500 barrels per day of sustainable oil from carbon waste at its first commercial plant. Photo via cemvita.com

Houston-based biotech company Cemvita has achieved a key production goal five years ahead of schedule.

Thanks to technology advancements, Cemvita is now capable of generating 500 barrels per day of sustainable oil from carbon waste at its first commercial plant. As a result, Cemvita has quadrupled output at the Houston plant. The company had planned to reach this milestone in 2029.

Cemvita, founded in 2017, says this achievement paves the way for increased production capacity, improved operational efficiency, and an elevated advantage in the sustainable oil market.

“What’s so amazing about synthetic biology is that humans are just scratching the surface of what’s possible,” says Moji Karimi, co-founder and CEO of Cemvita. “Our focus on the first principles has allowed us to design and create new biotech more cheaply and faster than ever before.”

The production achievement follows Cemvita’s recent breakthrough in development of a solvent-free extraction bioprocess.

In 2023, United Airlines agreed to buy up to one billion gallons of sustainable aviation fuel from Cemvita’s first full-scale plant over the course of 20 years.

Cemvita’s investors include the UAV Sustainable Flight Fund, an investment arm of Chicago-based United; Oxy Low Carbon Ventures, an investment arm of Houston-based energy company Occidental Petroleum; and Japanese equipment and machinery manufacturer Mitsubishi Heavy Industries.

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This article originally ran on InnovationMap.

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The BioWell, founded by biotech investor First Bight Ventures, was established to support sustainability-focused bioindustrial startups. Photo via Getty Images

New Houston bioindustrial accelerator to spark biotech-based sustainability

supporting startups

Bioindustrial technologies have a high potential for impacting sustainability — but they tend to need a little bit more help navigating the startup valley of death. That's where the BioWell comes in.

Carlos Estrada, head of Venture Acceleration at BioWell, says the idea for the accelerator was came to First Bight Ventures, a Houston-based biomanufacturing investment firm, as it began building its portfolio of promising companies.

"While we were looking at various companies, we found ourselves finding different needs that these startups have," Estrada says on the Houston Innovators Podcast. "That's how the opportunity for the BioWell came about."

Specifically, bioindustrial companies, which are tapping into life science innovation to create more sustainable products or services, need early funding, lab space, and strategic corporate partners to help research and develop their startups.

"The very direct challenge that we are seeing is that these companies very often have to spend their funds to build out their own lab spaces," Estrada says, "so by the time they're trying to focus back on the product itself, they are starting to run out of funding."

Carlos Estrada, head of Venture Acceleration at BioWell, joins the Houston Innovators Podcast to share why Houston is already a great hub for bioindustrial innovation. Photo courtesy of BioWell

BioWell is currently selecting its inaugural cohort and is also actively searching for its physical location to build out the program and facilities. Last year, BioWell secured $741,925 of the $53 million doled out as a part of the "Build to Scale" Grant program from the U.S. Economic Development Administration.

In addition to solving for specific challenges bioindustrial companies face, Estrada says the program will provide support for general startup and entrepreneurial guidance, like business plan development, navigating investors and grant funding, and more.

Just as First Bight Ventures was founded strategically in Houston to make the most of the local resources, the BioWell will operate out of the Bayou City — a market Estrada says has everything the industry needs.

"We have the right talent — our universities produce great researchers. We have the energy companies that are utilizing (a workforce) with transferable skills," he says on the show. "We also have the infrastructure, the square footage, and various real estate companies creating shells for lab space. We have the know how, the universities, and all at a lower cost, which plays a big role in the equation."

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This article originally ran on InnovationMap.

Calling all biotechnology startups focusing on sustainable feedstocks, commercially viable yields, and purpose fit microbes. Photo via Getty Images

Houston organization rolls out new accelerator to support companies tackling 'pressing global challenges'

CALLING FOR APPLICANTS

A Houston organization — freshly funded by a $700,000 U.S. Economic Development Administration’s “Build to Scale” grant — is seeking its first accelerator cohort of industrial biology startups.

Founded by Houston-based First Bight Ventures, the BioWell has launched a virtual accelerator program that will provide programming, networking, mentorship, and financial resources to its inaugural cohort of 10 bioindustrial startups. The selected companies will also have access to specialized pilot bioproduction infrastructure throughout the nine-month program.

“BioWell equips startups with more than just capital. We provide a foundation for breakthrough innovations by combining access to cutting-edge bioproduction facilities with expertise that nurtures scalability. This comprehensive support is crucial for transforming pioneering ideas into market-ready solutions that can address pressing global challenges,” Carlos Estrada, head of venture acceleration at BioWell, says in a news release.

Applications for the program are open until May 15, and the cohort will be announced in June. Specifically, BioWell is seeking seed or pre-seed startup applicants that have a technology readiness level of 3 to 5, focusing on areas including low-cost and sustainable feedstocks, commercially viable yields, and purpose fit microbes.

“During our selection process, we'll prioritize startups that demonstrate a commitment to not only hitting milestones but also to building sustainable revenue streams for long-term survival. This phase necessitates keen awareness of market dynamics, customer demands, and sound financial management,” adds First Bight Ventures and BioWell Founder Veronica Wu.

In December, BioWell secured $741,925 of the $53 million doled out as a part of the "Build to Scale" Grant program that the U.S. Economic Development Administration, a division of the U.S. Department of Commerce, has established. First Bight was one of 60 organizations to receive funding.

Ex-Apple exec Wu founded First Bight Ventures in Houston in 2022 after relocating from Silicon Valley and seeing the region's potential for biotech.

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This article originally ran on InnovationMap.

The opening of the pilot plant marks the debut of Cemvita’s eCO2 business as a wholly owned subsidiary. Photo courtesy of Cemvita

Fast-growing startup with carbon-free solution sets up pilot plant in Houston

big moves

Cleantech startup Cemvita has set up a pilot plant in its hometown of Houston to develop technology for converting carbon emissions as feedstock to make products like fertilizer, plastics, methane, and fuel.

The opening of the pilot plant marks the debut of Cemvita’s eCO2 business as a wholly owned subsidiary. The term eCO2 refers to equivalent carbon dioxide, or a way to measure a combination of greenhouse gases such as carbon dioxide and methane.

With a capacity of more than 14,000 gallons, the plant is producing eCO2 oil, an alternative to soybean oil. The company already is shipping samples of eCO2 products to customers, including renewable-fuel companies and plastics manufacturers.

Cemvita says the biofuel industry is facing feedstock shortages and price fluctuations. Biofuel feedstocks produce starches or sugars that can be converted to produce ethanol, while others produce oil that can be used in biodiesel production, according to the Sustainable Agriculture Research & Education (SARE) program.

“Traditional biofuels, including renewable diesel and sustainable aviation fuel, have relied on oils derived from crops, such as soybean and corn, as well as recycled vegetable oils,” Cemvita says. “As demand grows for petroleum-free alternatives, feedstock is in short supply and must compete with food markets. Crops of soybeans, sugar, and corn use huge swaths of land, and the raw materials require extensive refining — two factors that impede the processes from being sustainable.”

By contrast, eCO2 plants like Cemvita’s can supply feedstock production with minimal land and electricity requirements, and without relying on hydrogen or sunlight, the company says. Furthermore, the output of eCO2 plants is designed to carbon-negative, not just carbon-neutral.

Cemvita’s eCO2 biomanufacturing platform uses engineered microbes that absorb and convert carbon dioxide into feedstocks and finished products.

“The energy transition requires completely new, cost-effective approaches for heavy industry,” Charlie Nelson, chief operating officer of Cemvita, says in a news release. “We built this next-generation pilot plant in response to strong demand from … partners who are actively seeking sustainable solutions to the … feedstock shortage.”

Brother-and-sister team Moji and Tara Karimi founded Cemvita in 2017.

Investors in Cemvita include Oxy Low Carbon Ventures, an investment arm of Houston-based Occidental Petroleum, as well as BHP Group, Mitsubishi, and United Airlines Ventures.

Oxy Low Carbon Ventures and United Airlines Ventures are financing Cemvita’s work on sustainable jet fuel. United Airlines operates a hub at George Bush Intercontinental Airport Houston.

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This article originally ran on InnovationMap.

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Top 6 Houston energy events to attend in February 2025

Energy Events

Editor's note: February is here, and the month is buzzing with forums, conferences, and the largest AI in Energy event. Here are six Houston energy events that you won't want to miss this month. Mark your calendars now, and plan ahead for the rest of Q1 via this guide.

February 4 — 2025 Brazil Summit: Energy at a Crossroads 

The Brazil Summit, held at Rice University's Baker Institute, will explore Brazil’s evolving energy sector, including recent progress in energy transition regulations, as well as the 2024 U.S. election's implications for Brazil's future. Participants from Brazil and the U.S., including policymakers, energy leaders, financial experts and more, will join the summit, which is free to attend and open to the public.

This event takes place Tuesday, February 4, at 7:30 am. Registration is required. Click here to register.

February 10-11— 6th American LNG Forum

Join LNG industry professionals, innovators and policymakers to discover groundbreaking technologies that are driving the future of liquified natural gas. From market dynamics to decarbonization strategies, this is your chance to connect, learn and become part of the LNG revolution at American LNG Forum.

This event begins Monday, February 10, at the Westin Galleria Houston. Click here to register.

February 11-12 — Oil & Gas Automation and Technology Week 

Oil and Gas Automation and Technology Week brings together oil and gas operators to share best-practice strategies for accelerating business transformation, decarbonization, and energy transition with disruptive technology. Expert speakers from the automation and technology space include Jack Hu, Dow; Partha Chatterjee, Shell; and Philippe Daroux, Chevron.

The two-day event takes place at the Sonesta Houston Hotel IAH Airport. Click here to register.

February 19-20— 7th Global Energy Forum 2025

The Global Energy Forum brings a bipartisan collective of U.S. Congressmen together with top energy executives to convene for off-the-record discussions in order to explore the energy strategies and solutions for a sustainable, clean, reliable and affordable energy future. Policymakers and executives from energy, finance, and technology will engage in dialogue on energy infrastructure, technological innovation, policy and regulation reform needed to respond to the global energy crisis.

This event begins Wednesday, February 19, at 7:30 am at the Petroleum Club of Houston. Click here to register.

February 24-25 — AI In Energy

Join 150+ senior operations, digital, data and AI leaders in Houston for the industry's largest AI in Energy event, and unlock the potential of AI within your operations. Key points of discussion include how to pair digital twins and gen AI, know when your critical assets need maintenance, move beyond pilot program to scale AI across the enterprise, and leverage generative AI and data intelligence to unlock asset reliability.

This event begins Monday, February 24 at 7:30 am at Norris Conference Centers' City Centre. Click here to register.

February 25-27 — 2025 Energy HPC Conference

The 18th annual Energy High Performance Computing Conference, hosted at Rice University by the Ken Kennedy Institute, is the premier meeting place for the energy industry to engage in conversations about challenges and opportunities in high-performance computing, computational science and engineering, machine learning and data science. Attended by more than 500 leaders and experts, this is a unique opportunity for key stakeholders to engage and network to help advance HPC in the energy industry.

This event begins Tuesday, February 25, at Rice University. Click here to register.

Geothermal energy startup's $600M deal fuels surge in Houston VC funding

by the numbers

The venture capital haul for Houston-area startups jumped 23 percent from 2023 to 2024, according to the latest PitchBook-NVCA Venture Monitor.

The fundraising total for startups in the region climbed from $1.49 billion in 2023 to $1.83 billion in 2024, PitchBook-NVCA Venture Monitor data shows.

Roughly half of the 2024 sum, $914.3 million, came in the fourth quarter. By comparison, Houston-area startups collected $291.3 million in VC during the fourth quarter of 2023.

Among the Houston-area startups contributing to the impressive VC total in the fourth quarter of 2024 was geothermal energy startup Fervo Energy. PitchBook attributes $634 million in fourth-quarter VC to Fervo, with fulfillment services company Cart.com at $50 million, and chemical manufacturing platform Mstack and superconducting wire manufacturer MetOx International at $40 million each.

Across the country, VC deals total $209 billion in 2024, compared with $162.2 billion in 2023. Nearly half (46 percent) of all VC funding in North America last year went to AI startups, PitchBook says. PitchBook’s lead VC analyst for the U.S., Kyle Stanford, says that AI “continues to be the story of the market.”

PitchBook forecasts a “moderately positive” 2025 for venture capital in the U.S.

“That does not mean that challenges are gone. Flat and down rounds will likely continue at higher paces than the market is accustomed to. More companies will likely shut down or fall out of the venture funding cycle,” says PitchBook. “However, both of those expectations are holdovers from 2021.”

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This story originally appeared on our sister site, InnovationMap.com.

Halliburton's clean energy cohort tops trending news for January 2025

Trending News Tidbits

Editor's note: We're taking a look back at the top energy transition headlines from the second half of January 2025. Here are the five most-read EnergyCaptialHTX stories, from Halliburton's new clean energy cohort to Texas' top ranking among U.S. manufacturing hubs.

1. Halliburton names 5 clean energy startups to latest incubator cohort

Texas-based 360 Energy is part of Halliburton's new clean energy cohort. Photo courtesy of 360 Energy

Halliburton Labs has named five companies to its latest cohort, including one from Texas. All of the companies are working to help accelerate the future of the energy industry in different ways. The incubator aims to advance the companies’ commercialization with support from Halliburton's network, facilities and financing opportunities. Continue reading.

2. Houston Auto Show returns this month as part of new innovative coalition

The Houston Auto Show and Houston Boat Show (Houston AutoBoative) run from Jan. 2–Feb. 2. Photo via Houston Auto Show/Facebook

The Houston Auto Show and Houston Boat Show (Houston AutoBoative) returned to NRG Center this month, and for the first time, the popular events are part of the Automotive Experience Alliance (AEA). Launched in October, the AEA is a coalition of about 30 auto shows that aim to drive innovation and standardization throughout the auto show industry. Continue reading.

3. Being prepared: Has the Texas grid been adequately winterized?

How has the Texas grid improved since Winter Storm Uri in 2021? Getty Images

As Houston braced for historic winter weather, guest columnist Sam Luna, director at BKV Energy, asked the question on many Texans' minds each winter. In this article, Luna explores how the Texas grid has improved since Winter Storm Uri in 2021. Continue reading.

4. Geothermal exec on Houston expansion, commercialization and more

Axel-Pierre Bois, XGS Energy's Chief Technology Officer. Photo courtesy XGS Energy

Challenges in energy transition often center around two questions: Where will organizations find the resources? And how will projects be financed? XGS Energy's next-gen closed-loop geothermal well architecture addresses both issues head-on. The California-based company saw massive growth in the Houston market last year and recently completed a 100-meter field demonstration in central Texas, marking a major milestone for its technology's commercialization and potential for scale. In an interview with EnergyCapital, Axel-Pierre Bois, XGS's Chief Technology Officer, shares what drew him to the geothermal space, why XGS is expanding in Houston and what the company's plans are for the year ahead. Continue reading.

5. Texas ranks as No. 2 manufacturing hub in U.S., behind only California

A new study puts Texas at No. 2 among the states when it comes to manufacturing. Photo via Getty Images

Texas ranks among the country’s biggest hubs for manufacturing, according to a new study. The study, conducted by Chinese manufacturing components supplier YIJIN Hardware, puts Texas at No. 2 among the states when it comes to manufacturing-hub status. California holds the top spot. Continue reading.

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