The BioWell, founded by biotech investor First Bight Ventures, was established to support sustainability-focused bioindustrial startups. Photo via Getty Images

Bioindustrial technologies have a high potential for impacting sustainability — but they tend to need a little bit more help navigating the startup valley of death. That's where the BioWell comes in.

Carlos Estrada, head of Venture Acceleration at BioWell, says the idea for the accelerator was came to First Bight Ventures, a Houston-based biomanufacturing investment firm, as it began building its portfolio of promising companies.

"While we were looking at various companies, we found ourselves finding different needs that these startups have," Estrada says on the Houston Innovators Podcast. "That's how the opportunity for the BioWell came about."

Specifically, bioindustrial companies, which are tapping into life science innovation to create more sustainable products or services, need early funding, lab space, and strategic corporate partners to help research and develop their startups.

"The very direct challenge that we are seeing is that these companies very often have to spend their funds to build out their own lab spaces," Estrada says, "so by the time they're trying to focus back on the product itself, they are starting to run out of funding."

Carlos Estrada, head of Venture Acceleration at BioWell, joins the Houston Innovators Podcast to share why Houston is already a great hub for bioindustrial innovation. Photo courtesy of BioWell

BioWell is currently selecting its inaugural cohort and is also actively searching for its physical location to build out the program and facilities. Last year, BioWell secured $741,925 of the $53 million doled out as a part of the "Build to Scale" Grant program from the U.S. Economic Development Administration.

In addition to solving for specific challenges bioindustrial companies face, Estrada says the program will provide support for general startup and entrepreneurial guidance, like business plan development, navigating investors and grant funding, and more.

Just as First Bight Ventures was founded strategically in Houston to make the most of the local resources, the BioWell will operate out of the Bayou City — a market Estrada says has everything the industry needs.

"We have the right talent — our universities produce great researchers. We have the energy companies that are utilizing (a workforce) with transferable skills," he says on the show. "We also have the infrastructure, the square footage, and various real estate companies creating shells for lab space. We have the know how, the universities, and all at a lower cost, which plays a big role in the equation."

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This article originally ran on InnovationMap.

Calling all biotechnology startups focusing on sustainable feedstocks, commercially viable yields, and purpose fit microbes. Photo via Getty Images

Houston organization rolls out new accelerator to support companies tackling 'pressing global challenges'

CALLING FOR APPLICANTS

A Houston organization — freshly funded by a $700,000 U.S. Economic Development Administration’s “Build to Scale” grant — is seeking its first accelerator cohort of industrial biology startups.

Founded by Houston-based First Bight Ventures, the BioWell has launched a virtual accelerator program that will provide programming, networking, mentorship, and financial resources to its inaugural cohort of 10 bioindustrial startups. The selected companies will also have access to specialized pilot bioproduction infrastructure throughout the nine-month program.

“BioWell equips startups with more than just capital. We provide a foundation for breakthrough innovations by combining access to cutting-edge bioproduction facilities with expertise that nurtures scalability. This comprehensive support is crucial for transforming pioneering ideas into market-ready solutions that can address pressing global challenges,” Carlos Estrada, head of venture acceleration at BioWell, says in a news release.

Applications for the program are open until May 15, and the cohort will be announced in June. Specifically, BioWell is seeking seed or pre-seed startup applicants that have a technology readiness level of 3 to 5, focusing on areas including low-cost and sustainable feedstocks, commercially viable yields, and purpose fit microbes.

“During our selection process, we'll prioritize startups that demonstrate a commitment to not only hitting milestones but also to building sustainable revenue streams for long-term survival. This phase necessitates keen awareness of market dynamics, customer demands, and sound financial management,” adds First Bight Ventures and BioWell Founder Veronica Wu.

In December, BioWell secured $741,925 of the $53 million doled out as a part of the "Build to Scale" Grant program that the U.S. Economic Development Administration, a division of the U.S. Department of Commerce, has established. First Bight was one of 60 organizations to receive funding.

Ex-Apple exec Wu founded First Bight Ventures in Houston in 2022 after relocating from Silicon Valley and seeing the region's potential for biotech.

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This article originally ran on InnovationMap.

First Bight Venture's BioWell has received a $741,925 grant to continue supporting bioindustrial startups. Photo via Getty Images

Houston nonprofit accelerator receives grant funding to advance bioindustrial startups

the biowell

A Houston-based nonprofit accelerator that works with early-stage synthetic biology startups has secured nearly $750,000 to support its mission.

First Bight Ventures' accelerator, BioWell, secured $741,925 of the $53 million doled out as a part of the "Build to Scale" Grant program that the U.S. Economic Development Administration, a division of the U.S. Department of Commerce, has established. First Bight was one of 60 organizations to receive funding.

The funding will support the BioWell's mission to establish a "vibrant bioeconomy" by helping startups scale and commercialize "through access to a unique combination of pilot bioproduction infrastructure," according to a news release from First Bight.

"Startups at BioWell will gain access to a robust ecosystem, expertise, mentorship, and financial resources essential for successfully commercializing their bio-industrial innovations," BioWell Executive Director Paul Palmer says in the release.

The BioWell is still working toward establishing a physical space and has worked out of the East End Maker Hub in the meantime. The organization has partnered with Urban Partnerships Community Development Corporation, or UP CDC, which led the application process on this federal grant.

"BioWell chose to partner with UP CDC for the EDA grant, to continue the successful model that UP CDC has created at the East End Maker Hub for advanced manufacturing. UP CDC looks forward to continuing our partnership with BioWell in the UP CDC's BioCity project that will position Houston at the forefront of bio-manufacturing," UP CDC's CEO Patrick Ezzell says in the release.

First Bight Ventures Founder Veronica Wu established the BioWell to target high-potential startups, which usually have to overcome lack of funding challenges early on.

"Often times, early-stage startups gain momentum and hit important milestones, but ultimately find themselves heading toward the 'Valley of Death,' where progress is made on their enterprise, but no sufficient revenue is generated for the company's stability and longevity," Wu says in the release. "This 'Build to Scale' program's support will help offset these inevitable challenges in our bio-industrial space."

She shares more about her mission for First Bight Ventures on the Houston Innovators Podcast. Listen to the interview from March below.

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This article originally ran on InnovationMap.

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Houston energy startups, leaders named finalists for 2025 Innovation Awards

Meet the Innovators

InnovationMap.com, EnergyCaptialHTX's sister website, has revealed the finalists for the 2025 Houston Innovation Awards, and the local energy sector — from startups to leaders and accelerators — is well-represented throughout the awards.

Taking place on November 13 at Greentown Labs, the fifth annual Houston Innovation Awards will honor the best of Houston's innovation ecosystem, including startups, entrepreneurs, mentors, and more.

This year's finalists were determined by our esteemed panel of judges, comprised of past award winners and InnovationMap editorial leadership.

The panel reviewed nominee applications across 10 prestigious categories to determine the finalists. They will select the winner for each category, except for Startup of the Year, which will be chosen by the public via online voting launching later this month.

The Trailblazer Award recipient will be announced in the coming weeks, and the rest of this year's winners will be unveiled live at the annual awards ceremony and event on November 13 at Greentown Labs.

Tickets are on sale now — including a limited number of corporate 10-packs — secure yours today.

Without further ado, here are the 2025 Houston Innovation Awards finalists:

Minority-founded Business

Honoring an innovative startup founded or co-founded by BIPOC or LGBTQ+ representation:

  • Capwell Services
  • Deep Anchor Solutions
  • Mars Materials
  • Torres Orbital Mining (TOM)
  • Wellysis USA

Female-founded Business

Honoring an innovative startup founded or co-founded by a woman:

  • Anning Corporation
  • Bairitone Health
  • Brain Haven
  • FlowCare
  • March Biosciences
  • TrialClinIQ

Energy Transition Business

Honoring an innovative startup providing a solution within renewables, climatetech, clean energy, alternative materials, circular economy and beyond:

  • Anning Corporation
  • Capwell Services
  • Deep Anchor Solutions
  • Eclipse Energy
  • Loop Bioproducts
  • Mars Materials
  • Solidec

Health Tech Business

Honoring an innovative startup within the health and medical technology sectors:

  • Bairitone Health
  • Corveus Medical
  • FibroBiologics
  • Koda Health
  • NanoEar
  • Wellysis USA

Deep Tech Business

Honoring an innovative startup providing technology solutions based on substantial scientific or engineering challenges, including those in the AI, robotics and space sectors:

  • ARIX Technologies
  • Little Place Labs
  • Newfound Materials
  • Paladin Drones
  • Persona AI
  • Tempest Droneworx

Startup of the Year (People's Choice)

Honoring a startup celebrating a recent milestone or success. The winner will be selected by the community via an online voting experience:

  • Eclipse Energy
  • FlowCare
  • MyoStep
  • Persona AI
  • Rheom Materials
  • Solidec

Scaleup of the Year

Honoring an innovative later-stage startup that's recently reached a significant milestone in company growth:

  • Coya Therapeutics
  • Fervo Energy
  • Koda Health
  • Mati Carbon
  • Molecule
  • Utility Global

Incubator/Accelerator of the Year

Honoring a local incubator or accelerator that is championing and fueling the growth of Houston startups:

  • Activate
  • Energy Tech Nexus
  • Greentown Labs
  • Healthtech Accelerator (TMCi)
  • Impact Hub Houston

Mentor of the Year

Honoring an individual who dedicates their time and expertise to guide and support budding entrepreneurs. Presented by Houston Community College:

  • Anil Shetty, Inform AI
  • Jason Ethier, EnergyTech Nexus
  • Jeremy Pitts, Activate
  • Joe Alapat, Liongard
  • Neal Dikeman, Energy Transition Ventures
  • Nisha Desai, Intention

Trailblazer Recipient

  • To be announced
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Interested in sponsoring the 2025 Houston Innovation Awards? Contact sales@innovationmap.com for details.

Austin energy startup Base Power opens Katy office & expands Houston service

power move

An Austin startup that pairs electricity with backup power has started doing business in Houston.

Base Power announced this spring that it was entering the Houston market, with an initial focus on Cy-Fair, Spring, Cinco Ranch and Mission Bend. Now, Base Power is offering its service to households within the city of Houston.

To support its growth in the Houston area, Base Power has opened an office and warehouse in Katy. More than 30 people now work there. Plans to expand the Katy location are underway.

Base Power provides electricity that’s complemented by home backup power. Homes don’t need to be using solar power to sign up for Base Power’s service.

The startup said its service automatically supplies power to a home when the electric grid fails.

“Unlike traditional backup systems with high upfront costs, Base earns revenue by providing services to the grid — enabling Houstonians to get reliable backup and real savings,” Base Power said.

In addition to its standard service, Base Power has begun offering technology known as the Generator Recharge Port. This component allows a portable generator to plug into the Base battery system to recharge batteries during extended power outages.

“Houston has long been the energy capital of Texas, yet it has also endured some of the nation’s most painful lessons about unreliable power,” said Zach Dell, co-founder and CEO of Base Power. “We see Houston not just as a place to expand, but as a proving ground for how the future of energy should work — resilient, dependable, and built to serve homeowners when it matters most.”

Dell is the only son of Austin tech billionaire Michael Dell, a Houston native.

Base Power’s expansion in Houston adds to its Texas presence. The company now serves homeowners in the Houston, Dallas-Fort Worth and Austin areas. A partnership with homebuilder Lennar and collaborations with two utilities, GVEC and the Bandera Electric Cooperative, are helping drive Base Power’s business.

Base Power has raised more than $270 million in funding since its founding in 2023. This includes a $200 million series B round that will help finance construction of the company’s first factory in Texas and help fuel Base Power’s national expansion.

The startup’s investors include Andreessen Horowitz, Lightspeed Venture Partners, Valor Equity Partners, Thrive Capital, Altimeter, Terrain and Trust.

Houston hub for clean energy startups names global founding partners

green team

EnergyTech Nexus, a Houston-based hub for clean energy startups, announced its coalition of Global Founding Partners last month at its Pilotathon event during Houston Energy and Climate Week.

The group of international companies will contribute financial and technical resources, as well as share their expertise with startup founders, according to a news release from EnergyTech Nexus.

“Our Global Founding Partners represent the highest standards of industrial leadership, technical expertise and commitment to innovation,” Juliana Garaizar, co-founding partner of EnergyTech Nexus, added in the release. “Their collaboration enables us to connect groundbreaking technologies with the resources, infrastructure, and markets needed to achieve global scale.”

Houston-based partners include:

  • Cemvita Inc.
  • Chevron Technology Ventures
  • Collide
  • Greentown Labs
  • Kauel
  • Oxy Technology Ventures
  • Revterra
  • Sunipro

“At Collide, we believe progress happens when the right people, data, and ideas come together. Partnering with EnergyTech Nexus allows us to support innovators with the insights and community they need to accelerate deployment at scale,” Collin McLelland, co-founder and CEO of Collide, a provider of generative artificial intelligence for the energy sector, said in the release.

"Revterra is thrilled to be a founding member of the EnergyTech Nexus community," Ben Jawdat, founder and CEO of kinetic battery technology company Revterra, added. "Building a strong network of collaborators, customers, and investors is critical for any startup — particularly when you're building novel hardware. The Energytech Nexus community has been incredible at bringing all of the right stakeholders together."

Other partners, many of which have a strong presence in Houston, include:

  • BBVA
  • EarthX
  • Endress+Hauser
  • Goodwin
  • Greenbackers Investment Capital
  • ISR Energy
  • Latham & Watkins LLP
  • Ormazabal
  • Repsol
  • STX Next
  • XGS Energy

Jason Ethier, co-founding partner of EnergyTech Nexus, said that partnerships with these companies will be "pivotal" in supporting the organization's community of founders and Houston's broader energy transition sector.

“The Energy and Climate industry deploys over $1.5 trillion in capital every year to meet our growing energy demands. Our global founding partners recognize that this energy must be delivered reliably, cost effectively, and sustainably, and have committed to ensuring that technology developed without our ecosystem can find a path to market through testing and piloting in real-world conditions," Ethier said. "The ecosystem they support here solidifies Houston as the global nexus for the energy transition.”

EnergyTech Nexus also recently announced a "strategic ecosystem partnership" with Greentown Labs, aimed at accelerating growth for clean energy startups. Read more here.