The BioWell, founded by biotech investor First Bight Ventures, was established to support sustainability-focused bioindustrial startups. Photo via Getty Images

Bioindustrial technologies have a high potential for impacting sustainability — but they tend to need a little bit more help navigating the startup valley of death. That's where the BioWell comes in.

Carlos Estrada, head of Venture Acceleration at BioWell, says the idea for the accelerator was came to First Bight Ventures, a Houston-based biomanufacturing investment firm, as it began building its portfolio of promising companies.

"While we were looking at various companies, we found ourselves finding different needs that these startups have," Estrada says on the Houston Innovators Podcast. "That's how the opportunity for the BioWell came about."

Specifically, bioindustrial companies, which are tapping into life science innovation to create more sustainable products or services, need early funding, lab space, and strategic corporate partners to help research and develop their startups.

"The very direct challenge that we are seeing is that these companies very often have to spend their funds to build out their own lab spaces," Estrada says, "so by the time they're trying to focus back on the product itself, they are starting to run out of funding."

Carlos Estrada, head of Venture Acceleration at BioWell, joins the Houston Innovators Podcast to share why Houston is already a great hub for bioindustrial innovation. Photo courtesy of BioWell

BioWell is currently selecting its inaugural cohort and is also actively searching for its physical location to build out the program and facilities. Last year, BioWell secured $741,925 of the $53 million doled out as a part of the "Build to Scale" Grant program from the U.S. Economic Development Administration.

In addition to solving for specific challenges bioindustrial companies face, Estrada says the program will provide support for general startup and entrepreneurial guidance, like business plan development, navigating investors and grant funding, and more.

Just as First Bight Ventures was founded strategically in Houston to make the most of the local resources, the BioWell will operate out of the Bayou City — a market Estrada says has everything the industry needs.

"We have the right talent — our universities produce great researchers. We have the energy companies that are utilizing (a workforce) with transferable skills," he says on the show. "We also have the infrastructure, the square footage, and various real estate companies creating shells for lab space. We have the know how, the universities, and all at a lower cost, which plays a big role in the equation."

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This article originally ran on InnovationMap.

Calling all biotechnology startups focusing on sustainable feedstocks, commercially viable yields, and purpose fit microbes. Photo via Getty Images

Houston organization rolls out new accelerator to support companies tackling 'pressing global challenges'

CALLING FOR APPLICANTS

A Houston organization — freshly funded by a $700,000 U.S. Economic Development Administration’s “Build to Scale” grant — is seeking its first accelerator cohort of industrial biology startups.

Founded by Houston-based First Bight Ventures, the BioWell has launched a virtual accelerator program that will provide programming, networking, mentorship, and financial resources to its inaugural cohort of 10 bioindustrial startups. The selected companies will also have access to specialized pilot bioproduction infrastructure throughout the nine-month program.

“BioWell equips startups with more than just capital. We provide a foundation for breakthrough innovations by combining access to cutting-edge bioproduction facilities with expertise that nurtures scalability. This comprehensive support is crucial for transforming pioneering ideas into market-ready solutions that can address pressing global challenges,” Carlos Estrada, head of venture acceleration at BioWell, says in a news release.

Applications for the program are open until May 15, and the cohort will be announced in June. Specifically, BioWell is seeking seed or pre-seed startup applicants that have a technology readiness level of 3 to 5, focusing on areas including low-cost and sustainable feedstocks, commercially viable yields, and purpose fit microbes.

“During our selection process, we'll prioritize startups that demonstrate a commitment to not only hitting milestones but also to building sustainable revenue streams for long-term survival. This phase necessitates keen awareness of market dynamics, customer demands, and sound financial management,” adds First Bight Ventures and BioWell Founder Veronica Wu.

In December, BioWell secured $741,925 of the $53 million doled out as a part of the "Build to Scale" Grant program that the U.S. Economic Development Administration, a division of the U.S. Department of Commerce, has established. First Bight was one of 60 organizations to receive funding.

Ex-Apple exec Wu founded First Bight Ventures in Houston in 2022 after relocating from Silicon Valley and seeing the region's potential for biotech.

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This article originally ran on InnovationMap.

First Bight Venture's BioWell has received a $741,925 grant to continue supporting bioindustrial startups. Photo via Getty Images

Houston nonprofit accelerator receives grant funding to advance bioindustrial startups

the biowell

A Houston-based nonprofit accelerator that works with early-stage synthetic biology startups has secured nearly $750,000 to support its mission.

First Bight Ventures' accelerator, BioWell, secured $741,925 of the $53 million doled out as a part of the "Build to Scale" Grant program that the U.S. Economic Development Administration, a division of the U.S. Department of Commerce, has established. First Bight was one of 60 organizations to receive funding.

The funding will support the BioWell's mission to establish a "vibrant bioeconomy" by helping startups scale and commercialize "through access to a unique combination of pilot bioproduction infrastructure," according to a news release from First Bight.

"Startups at BioWell will gain access to a robust ecosystem, expertise, mentorship, and financial resources essential for successfully commercializing their bio-industrial innovations," BioWell Executive Director Paul Palmer says in the release.

The BioWell is still working toward establishing a physical space and has worked out of the East End Maker Hub in the meantime. The organization has partnered with Urban Partnerships Community Development Corporation, or UP CDC, which led the application process on this federal grant.

"BioWell chose to partner with UP CDC for the EDA grant, to continue the successful model that UP CDC has created at the East End Maker Hub for advanced manufacturing. UP CDC looks forward to continuing our partnership with BioWell in the UP CDC's BioCity project that will position Houston at the forefront of bio-manufacturing," UP CDC's CEO Patrick Ezzell says in the release.

First Bight Ventures Founder Veronica Wu established the BioWell to target high-potential startups, which usually have to overcome lack of funding challenges early on.

"Often times, early-stage startups gain momentum and hit important milestones, but ultimately find themselves heading toward the 'Valley of Death,' where progress is made on their enterprise, but no sufficient revenue is generated for the company's stability and longevity," Wu says in the release. "This 'Build to Scale' program's support will help offset these inevitable challenges in our bio-industrial space."

She shares more about her mission for First Bight Ventures on the Houston Innovators Podcast. Listen to the interview from March below.

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This article originally ran on InnovationMap.

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Rice University team develops eco-friendly method to destroy 'forever chemicals' in water

clean water research

Rice University researchers have teamed up with South Korean scientists to develop the first eco-friendly technology that captures and destroys toxic “forever chemicals,” or PFAS, in water.

PFAS have been linked to immune system disruption, certain cancers, liver damage and reproductive disorders. They can be found in water, soil and air, as well as in products like Teflon pans, waterproof clothing and food packaging. They do not degrade easily and are difficult to remove.

Thus far, PFAS cleanup methods have relied on adsorption, in which molecules cling to materials like activated carbon or ion-exchange resins. But these methods tend to have limited capacity, low efficiency, slow performance and can create additional waste.

The Rice-led study, published in the journal Advanced Materials, centered on a layered double hydroxide (LDH) material made from copper and aluminum that could rapidly capture PFAS and be used to destroy the chemicals.

The study was led by Rice professor Youngkun Chung, a postdoctoral fellow under the mentorship of Michael S. Wong. It was conducted in collaboration with Seoktae Kang, professor at the Korea Advanced Institute of Science and Technology, and Keon-Ham Kim, professor at Pukyung National University, who first discovered the LDH material.

The team evaluated the LDH material in river water, tap water and wastewater. And, according to Rice, that material’s unique copper-aluminum layers and charge imbalances created an ideal binding environment to capture PFAS molecules.

“To my astonishment, this LDH compound captured PFAS more than 1,000 times better than other materials,” Chung, lead author of the study and now a fellow at Rice’s WaTER (Water Technologies, Entrepreneurship and Research) Institute and Sustainability Institute, said in a news release. “It also worked incredibly fast, removing large amounts of PFAS within minutes, about 100 times faster than commercial carbon filters.”

Next, Chung, along with Rice professors Pedro Alvarez and James Tour, worked to develop an eco-friendly, sustainable method of thermally decomposing the PFAS captured on the LDH material. They heated saturated material with calcium carbonate, which eliminated more than half of the trapped PFAS without releasing toxic by-products.

The team believes the study’s results could potentially have large-scale applications in industrial cleanups and municipal water treatments.

“We are excited by the potential of this one-of-a-kind LDH-based technology to transform how PFAS-contaminated water sources are treated in the near future,” Wong added in the news release. “It’s the result of an extraordinary international collaboration and the creativity of young researchers.”

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This article originally appeared on our sister site, InnovationMap.

6 must-attend Houston energy sector events in November 2025

Must-Attend Meetings

Editor's note: It's time to mark your calendar for November's must-attend Houston energy transition events, as they are front-loaded at the beginning fo the month. From a climatetech summit to the annual Houston Innovation Awards, these are the energy events to attend. Learn more below, and register now.

Nov. 4: Greentown Labs Climatetech Summit

Greentown Labs hosts its Houston Climatetech Summit, bringing together philanthropists, executives, and innovators in the energy transition space. Attendees will be able to explore climatetech solutions from dozens of startups, as well as hear insightful keynotes and discussions with industry leaders throughout the day.

The event begins with check-in and breakfast at 8 am on Nov. 4 at Greentown Labs. Register here.

Nov. 4-6: Operational Excellence in Oil and Gas Summit 2025

More than 300 industry leaders and change-makers will explore smarter, faster, more sustainable paths to operational excellence in the oil and gas industry at this annual three-day summit.

The event begins Nov. 4 at Norris Conference Center - City Centre Location. Register here.

Nov. 11-12: 20th Annual API Cybersecurity Conference for the Oil and Natural Gas Industry

The API Cybersecurity Conference has been an annual event since 2005. For 20 years, it has been the only cybersecurity conference dedicated to the oil and gas industry. Don't miss two days of compelling programming, networking and idea-exchange opportunities, as well as exhibitors sharing the latest products and services.

The event begins Nov. 11 at Woodlands Waterway Marriott. Register here.

Nov. 12-13: Energy Supply Chain & Procurement Summit

Senior executives from across the U.S. come to Houston, the energy capital, to discuss the energy supply chain, procurement and logistics ecosystems. The summit is focused on fostering dialogue and facilitating commercial relationships to further the mission of decarbonization and digitalization of the energy sector.

The event begins Nov. 12 at Hyatt Regency Houston West. Register here.

Nov. 13: Houston Innovation Awards

Houston's innovation ecosystem comes together for the fifth annual Houston Innovation Awards, taking place for the first time at Greentown Labs. Get your tickets to this intimate networking event and awards program, where winners in 10 prestigious categories — including Energy Transition Business, Scaleup of the Year, and Startup of the Year — will be revealed.

The event begins at 7 pm on Nov. 13 at Greentown Labs. Tickets are available here.

Nov. 14: Powering the Future via Geothermal, Lithium Extraction, and Battery Storage

Innovators and energy experts will converge for an in-depth panel discussion on how geothermal energy, lithium extraction and battery storage are shaping the next era of the low-carbon economy. At this event, hosted by Society for Low Carbon technologies, attendees will engage with thought leaders across sectors and explore how these technologies will help power a cleaner and smarter energy future.

This event begins at 9:10 am on Nov. 14 at NOV Towers. Register here.

Houston energy giants among top AI adopters and more news to know

Trending Topics

Editor's note: The top energy transition news for Oct. 15-31 includes AI integration among energy leaders and the most promising startups from an annual pitch competition. Here are the most-read EnergyCapitalHTX stories for the second half of October:

1. 2 Houston energy giants appear on Fortune’s inaugural AI ranking

ExxonMobil is on Fortune's first-ever AIQ ranking. Getty Images

Two Houston-area energy leaders appear on Fortune’s inaugural list of the top adopters of AI among Fortune 500 companies. They are: No. 7 energy company ExxonMobil, based in Spring and No. 47 energy company Chevron, based in Houston. They are joined by Spring-based tech company Hewlett Packard Enterprise, No. 19. All three companies have taken a big dive into the AI pool. Continue reading.

2. Energy Tech Nexus names 8 startup winners from Pilotathon pitch event

Eight startups were given awards at Energy Tech Nexus' Pilotathon. Photo via Getty Images.

Energy Tech Nexus held its Pilotathon and Showcase during the second annual Houston Energy & Climate Startup Week last month and granted awards to eight startups. This year's event, focused on the theme "Energy Access and Resilience," offered 24 startups an opportunity to pitch their pilot projects. Continue reading.

3. Houston organization proposes Gulf Coast index for hydrogen market

The Clean Hydrogen Buyers Alliance plans to create the Gulf Coast Hydrogen Index to bring to bring transparency and confidence to hydrogen pricing. Photo via Getty Images

The Clean Hydrogen Buyers Alliance has proposed an index aimed at bringing transparency to pricing in the emerging hydrogen market. The Houston-based alliance said the Gulf Coast Hydrogen Index, based on real-time data, would provide more clarity to pricing in the global market for hydrogen. The benchmarking effort is being designed to benefit clean hydrogen buyers, sellers and investors. The index would help position the U.S. “as the trading anchor for hydrogen’s next chapter as a globally traded commodity,” the alliance said. Continue reading.

4. Houston clean energy company to develop hybrid renewable project in Port Arthur

The new Pleasure Island Power Collective in Port Arthur is expected to generate 391 megawatts of clean power. Photo via unsplash.

Houston-based clean energy company Diligence Offshore Services has announced a strategic partnership with Florida-based floating solar manufacturing company AccuSolar for the development of a renewable energy project in the Port Arthur area. Known as the Pleasure Island Power Collective, it will be built on 2,275 acres across Pleasure Island and Sabine Lake. It is expected to generate 391 megawatts of clean power, alongside a utility-scale battery energy storage system. Continue reading.

5. Port Houston reports emissions progress as cargo volumes climb

Ric Campo says Port Houston is “moving in the right direction.” Photo via Getty Images.

Port Houston’s initiatives to reduce emissions have shown some positive results, according to new data from the Port of Houston Authority. Pulling from the Goods Movement Emissions Inventory (GMEI) report, which tracks port-related air emissions, Port Houston cited several improvements compared to the most recent report from 2019. Continue reading.