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New Houston bioindustrial accelerator to spark biotech-based sustainability

supporting startups

The BioWell, founded by biotech investor First Bight Ventures, was established to support sustainability-focused bioindustrial startups. Photo via Getty Images

Bioindustrial technologies have a high potential for impacting sustainability — but they tend to need a little bit more help navigating the startup valley of death. That's where the BioWell comes in.

Carlos Estrada, head of Venture Acceleration at BioWell, says the idea for the accelerator was came to First Bight Ventures, a Houston-based biomanufacturing investment firm, as it began building its portfolio of promising companies.

"While we were looking at various companies, we found ourselves finding different needs that these startups have," Estrada says on the Houston Innovators Podcast. "That's how the opportunity for the BioWell came about."

Specifically, bioindustrial companies, which are tapping into life science innovation to create more sustainable products or services, need early funding, lab space, and strategic corporate partners to help research and develop their startups.

"The very direct challenge that we are seeing is that these companies very often have to spend their funds to build out their own lab spaces," Estrada says, "so by the time they're trying to focus back on the product itself, they are starting to run out of funding."

Carlos Estrada, head of Venture Acceleration at BioWell, joins the Houston Innovators Podcast to share why Houston is already a great hub for bioindustrial innovation. Photo courtesy of BioWell

BioWell is currently selecting its inaugural cohort and is also actively searching for its physical location to build out the program and facilities. Last year, BioWell secured $741,925 of the $53 million doled out as a part of the "Build to Scale" Grant program from the U.S. Economic Development Administration.

In addition to solving for specific challenges bioindustrial companies face, Estrada says the program will provide support for general startup and entrepreneurial guidance, like business plan development, navigating investors and grant funding, and more.

Just as First Bight Ventures was founded strategically in Houston to make the most of the local resources, the BioWell will operate out of the Bayou City — a market Estrada says has everything the industry needs.

"We have the right talent — our universities produce great researchers. We have the energy companies that are utilizing (a workforce) with transferable skills," he says on the show. "We also have the infrastructure, the square footage, and various real estate companies creating shells for lab space. We have the know how, the universities, and all at a lower cost, which plays a big role in the equation."

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This article originally ran on InnovationMap.

Calling all biotechnology startups focusing on sustainable feedstocks, commercially viable yields, and purpose fit microbes. Photo via Getty Images

Houston organization rolls out new accelerator to support companies tackling 'pressing global challenges'

CALLING FOR APPLICANTS

A Houston organization — freshly funded by a $700,000 U.S. Economic Development Administration’s “Build to Scale” grant — is seeking its first accelerator cohort of industrial biology startups.

Founded by Houston-based First Bight Ventures, the BioWell has launched a virtual accelerator program that will provide programming, networking, mentorship, and financial resources to its inaugural cohort of 10 bioindustrial startups. The selected companies will also have access to specialized pilot bioproduction infrastructure throughout the nine-month program.

“BioWell equips startups with more than just capital. We provide a foundation for breakthrough innovations by combining access to cutting-edge bioproduction facilities with expertise that nurtures scalability. This comprehensive support is crucial for transforming pioneering ideas into market-ready solutions that can address pressing global challenges,” Carlos Estrada, head of venture acceleration at BioWell, says in a news release.

Applications for the program are open until May 15, and the cohort will be announced in June. Specifically, BioWell is seeking seed or pre-seed startup applicants that have a technology readiness level of 3 to 5, focusing on areas including low-cost and sustainable feedstocks, commercially viable yields, and purpose fit microbes.

“During our selection process, we'll prioritize startups that demonstrate a commitment to not only hitting milestones but also to building sustainable revenue streams for long-term survival. This phase necessitates keen awareness of market dynamics, customer demands, and sound financial management,” adds First Bight Ventures and BioWell Founder Veronica Wu.

In December, BioWell secured $741,925 of the $53 million doled out as a part of the "Build to Scale" Grant program that the U.S. Economic Development Administration, a division of the U.S. Department of Commerce, has established. First Bight was one of 60 organizations to receive funding.

Ex-Apple exec Wu founded First Bight Ventures in Houston in 2022 after relocating from Silicon Valley and seeing the region's potential for biotech.

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This article originally ran on InnovationMap.

First Bight Venture's BioWell has received a $741,925 grant to continue supporting bioindustrial startups. Photo via Getty Images

Houston nonprofit accelerator receives grant funding to advance bioindustrial startups

the biowell

A Houston-based nonprofit accelerator that works with early-stage synthetic biology startups has secured nearly $750,000 to support its mission.

First Bight Ventures' accelerator, BioWell, secured $741,925 of the $53 million doled out as a part of the "Build to Scale" Grant program that the U.S. Economic Development Administration, a division of the U.S. Department of Commerce, has established. First Bight was one of 60 organizations to receive funding.

The funding will support the BioWell's mission to establish a "vibrant bioeconomy" by helping startups scale and commercialize "through access to a unique combination of pilot bioproduction infrastructure," according to a news release from First Bight.

"Startups at BioWell will gain access to a robust ecosystem, expertise, mentorship, and financial resources essential for successfully commercializing their bio-industrial innovations," BioWell Executive Director Paul Palmer says in the release.

The BioWell is still working toward establishing a physical space and has worked out of the East End Maker Hub in the meantime. The organization has partnered with Urban Partnerships Community Development Corporation, or UP CDC, which led the application process on this federal grant.

"BioWell chose to partner with UP CDC for the EDA grant, to continue the successful model that UP CDC has created at the East End Maker Hub for advanced manufacturing. UP CDC looks forward to continuing our partnership with BioWell in the UP CDC's BioCity project that will position Houston at the forefront of bio-manufacturing," UP CDC's CEO Patrick Ezzell says in the release.

First Bight Ventures Founder Veronica Wu established the BioWell to target high-potential startups, which usually have to overcome lack of funding challenges early on.

"Often times, early-stage startups gain momentum and hit important milestones, but ultimately find themselves heading toward the 'Valley of Death,' where progress is made on their enterprise, but no sufficient revenue is generated for the company's stability and longevity," Wu says in the release. "This 'Build to Scale' program's support will help offset these inevitable challenges in our bio-industrial space."

She shares more about her mission for First Bight Ventures on the Houston Innovators Podcast. Listen to the interview from March below.

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This article originally ran on InnovationMap.

Greentown Houston has received funding from the EDA. Photo via GreentownLabs.com

Greentown Houston selected for federal program that's accelerating tech entrepreneurship

seeing green

Sixty organizations across the country have received a grant from the United States Department of Commerce — and one recipient is based in Houston.

Greentown Labs, dual located in Houston and Somerville, Massachusetts, has received a grant from the 10th cohort of the Economic Development Administration's “Build to Scale” program for its Houston location. The $53 million of funding was awarded to 60 organizations across 36 states, the District of Columbia, and Puerto Rico. All of the programs support technology entrepreneurs across industries.

“The Biden-Harris Administration is Investing in America to help create entrepreneurial ecosystems across the country and put quality, 21st century job opportunities in people’s backyards,” Secretary of Commerce Gina Raimondo says in the press release. “The ‘Build to Scale’ program will unlock innovation potential in regions all over the nation, improving our economic competitiveness now, and for decades to come.”

According to the EDA, Greentown, located in a growing innovation district, will receive $400,000 with a $400,000 local match confirmed. The project, named Houston Ion District Investor Activation, is described as a way to create economic opportunity through equitable capital access.

"This project capitalizes on the need for jobs and economic development, especially in communities most vulnerable to the impacts of natural disasters," reads the project abstract. "EDA funding will enable the expansion of Greentown’s Investor Program into EDIJ, in partnership with the Ion, to further climate equity and resilience in Houston and empower underrepresented entrepreneurs as the city transitions from fossil fuels to a clean energy economy."

Greentown receives of of the 2023 Capital Challenge Grant Recipients. The other competition, the Venture Challenge, also awarded funding to another Houston organization. The Urban Partnerships Community Development Corporation received $741,925 to support the BioWell Start Accelerator Program, which is committed to scaling of bio-industrial startups.

“EDA is proud to partner with this year’s ‘Build to Scale’ grantees as they fuel regional innovation hubs and technology-based economic development strategies throughout the U.S.,” Assistant Secretary of Commerce for Economic Development Alejandra Y. Castillo says in the release. “Investing in scalable startups and expanding access entrepreneurial capital will yield good-paying jobs, economic resiliency, and equitable growth in communities throughout America.”

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Woodside Energy names new CEO with sustainability focus

new leader

Woodside Energy has officially named Elizabeth Westcott as its new managing director and CEO.

Westcott has served as the company's acting CEO since Meg O'Neill stepped down in December 2025. Woodside is headquartered in Australia with its global operations based in Houston.

Before joining Woodside as executive vice president of Australian Operations in 2023, Westcott served as COO at EnergyAustralia. She has also held leadership roles at ExxonMobil and Adriatic LNG.

At Woodside, she has overseen the $12.5 Scarborough Energy Project, which the company says is expected to be one of the lowest-carbon-intensity sources of LNG, as well as other major projects and initiatives.

“My focus as CEO is on sustainable value creation for Woodside shareholders, operational excellence and disciplined execution of our growth projects," Westcott said in a news release. “I look forward to working closely with the Board and Woodside’s strong leadership team to continue building a leading global energy company that delivers long-term value for shareholders, underpinned by a consistent focus on sustainability and high performance.”

Woodside Chair Richard Goyder added that Westcott was the top choice for the role.

“Liz’s proven track record of outstanding strategic leadership and disciplined delivery distinguished her as the Board’s top candidate for this role," Goyder said. “Liz’s extensive industry experience and strategic vision will be invaluable in leading Woodside at this significant moment in its history.”

Earlier this month, Westcott spoke on how sustainability is a priority for Woodside.

"Put simply, sustainable business is good business ... Because strong sustainability performance is not only the right thing to do. It also drives long-term value by helping to de-risk our business, secure future opportunities and support a compelling value proposition for investors," she said in her 2026 sustainability briefing.

Westcott called attention to the company's Beaumont New Ammonia project. The company acquired the Texas-based clean ammonia project in 204 for $2.35 billion. Production of lower‑carbon ammonia was initially expected sometime this year, but Westcott shared that delivery has been pushed back due to construction delays.

Read Westcott's full suitability briefing here.

30+ CERAWeek events featuring Houston energy leaders

where to be

CERAWeek returns to Houston March 23-27, bringing more than 1,000 speakers, executives and energy innovators to Houston.

Under this year's theme, "Convergence and Competition: Energy, Technology and Geopolitics,” panels will tackle topics ranging from policy and global relations to the growing role of AI in the energy sector. Most of the innovation-themed events are organized under the Agora track and will feature many Houston-area startups, universities, companies and scientists. Panels will feature leaders from Fortune 500 companies and top U.S. government officials, scientists and founders pushing towards a more carbon-neutral future.

Here are some of the many events featuring Houston leaders on the Agora track you can't miss if you want to learn more about Houston energy innovation.

Monday, March 23rd


Scaling Innovation: Building the ecosystem for the next energy breakthroughs

Featuring: Georgina Campbell Flatter, CEO of Greentown Labs

This event is at 10:30 a.m. Find more info here

Vaulted Deep | The Subsurface as Waste and Carbon Infrastructure

Featuring: Julia Reichelstein, co-founder and CEO of Vaulted Deep

This event is at 11:30 a.m. Find more info here

Collaboration Spotlight | Collision Course: How Houston's Ion District turns proximity into innovation

Featuring: Adrian Tromel, chief innovation officer at Rice University; Rawand Rasheed, co-founder and CEO of Helix Earth Technologies; Marc Davidson, senior technical advisor at Veriten

This event is at 1:30 p.m. Find more info here.

Methane Reduction in Practice: Field learnings

Featuring: Matt Kolesar, chief environmental scientist at ExxonMobil

This event is at 2 p.m. Find more info here.

Time-to-AI: Shrinking the data-center clock

Featuring: Robert Ott, vice president of wholesale origination at NRG Energy; Andrew Johnston, business line director, data centers at SLB

This event is at 2:30 p.m. Find more info here.

Scaling CCUS: Which industries, regions and funding sources?

Featuring: Gino Thielens, vice president of renewables and energy efficiency at SLB; Ian McIntyre, senior vice president, 1PointFive

This event is at 3 p.m. Find more info here.

Democratization of AI: Redefining where work gets done

Featuring: Rob Crane, technology scouting and venturing manager at SLB

This event is at 3:30 p.m. Find more info here.

Tuesday, March 24th


Syzygy Plasmonics | Affordable, Globally Compliant SAF Using Abundant Biogas Feedstock

Featuring: Trevor Best, CEO and founder of Syzygy Plasmonics

This event is at noon. Find more info here.

Accelerating Idea to Impact: Carving new ways to innovation

Featuring: David Sholl, executive vice president for research at Rice University

This event is at 1 p.m. Find more info here.

NRG | From the Front Lines: A deep dive into grid reliability

Featuring: Matthew Pistner, senior vice president of generation at NRG Energy; Robert Patrick, vice president of development engineering and construction at NRG Energy

This event is at 1:30 p.m. Find more info here.

Energy Efficiency: The industrial advantage

Featuring: Jason Urso, CTO of Honeywell Industrial Automation

This event is at 1:30 p.m. Find more info here.

The CEO Blueprint | Strategy

Featuring: Lorenzo Simonelli, CEO and chairman of Baker Hughes

This event is at 2:55 p.m. Find more info here.

Occidental | Beyond the Technology: Turning direct air capture into CDR credits

Featuring: William Barrett, vice president of product development at 1PointFive

This event is at 3:30 p.m. Find more info here.

Wednesday, March 25th


Innovations in Sustainable Steel

Featuring: Laureen Meroueh, founder and CEO of Heartha Metals Inc.

This event is at 9 a.m. Find more info here.

Rice University | The Science of Geologic Carbon Storage

Featuring: Sahar Bakhshian, assistant professor, earth, environmental and planetary sciences at Rice University

This event is at 9:30 a.m. Find more info here.

Sparking Innovation: The impact of interdisciplinary collaboration

Featuring: Marie Contou Carrere, executive director of the Rice Sustainability Institute; Sandy Guitar, executive director of TEX-E

This event is at 10 a.m. Find more info here.

Models of Innovation, Models of Capital

Featuring: Bobby Tudor, chair of Houston Energy Transition Initiative and chairman of the board for Greentown Labs

This event is at 10:30 a.m. Find more info here.

Energy Venture Day and Pitch Competition

This event is at noon. Find more info here. Learn more about the competing teams here.

Baker Hughes | Meeting Industrial and AI-Driven Energy Demand with Flexible, Reliable and Sustainable Power Solutions

Featuring: Daniele Marcucci, industrial power generation product director at Baker Hughes; Florent Rousset, geothermal leader, new energies at Baker Hughes

This event is at noon. Find more info here.

Thursday, March 26th


Mission-driven Minds: How space exploration inspires the next generation of energy innovators

Featuring: Trina Sadberry, head of brand & engagement in the United States at Equinor; Laura Dandridge, corporate affairs advisor at Chevron; Jack Fischer, chief integration officer at Intuitive Machines; Ginger Kerrick Davis, chief strategy officer at Barrios Technology

This event is at 9 a.m. Find more info here.

Rice University | Nature-based Solutions: A focus on biochar and enhanced rock weathering

Featuring: Carrie Masiello, director of the sustainability institute at Rice University; Mark Torres, associate professor, earth, environmental and planetary sciences at Rice University

This event is at 9:30 a.m. Find more info here.

Growing Direct Air Capture

Featuring: Anthony Cottone, resident and general manager at 1PointFive

This event is at 9:30 a.m. Find more info here.

Occidental | Advancement and Growth Opportunities for Enhanced Oil Recovery

Featuring: Vishal Gupta, president and general manager of EOR Ventures at Occidental

This event is at 9:30 a.m. Find more info here.

Geothermal: Charting progress on technological advancements

Featuring: Jonathan Ajo-Franklin, trustee professor, earth, environmental and planetary sciences at Rice University; Florent Rousset, geothermal leader, new energies at Baker Hughes

This event is at 10 a.m. Find more info here.

Newfound Materials | Bridging the Synthesis Gap in AI-Driven Materials Innovation

Featuring: Matt McDermott, founder and CEO of Newfound Materials

This event is at 10 a.m. Find more info here.

Hertha Metals | The Future of Steel Production: Going beyond the blast furnace

Featuring: Laureen Meroueh, founder and CEO of Heartha Metals Inc.

This event is at 11 a.m. Find more info here.

Advanced Materials with Low-Carbon Intensity

Featuring: Matteo Pasquali, director of the Rice Carbon Hub

This event is at 11:30 a.m. Find more info here.

Lessons from the Lab: Common pitfalls of hard tech startups

Featuring: Jeremy Pitts, managing director of Activate Houston

This event is at 11:30 a.m. Find more info here.

TotalEnergies | Accelerating Direct Air Capture

Featuring: Isabelle Betremieux, head of R&T CO2 capture department at TotalEnergies

This event is at 1 p.m. Find more info here.

Spotlight: "NextGen" energy leaders of the future

Featuring: Renu Khator, chancellor and president of the University of Houston

This event is at 3 p.m. Find more info here.

Solidec | On-site, On-demand Production of Essential Chemicals

Featuring: Ryan DuChanois, co-founder and CEO of Solidec

This event is at 3:30 p.m. Find more info here.

Fervo secures $421M in financing for Cape Station construction

fresh funding

Houston geothermal unicorn Fervo Energy has closed $421 million in non-recourse debt financing for the first phase of its flagship Cape Station project in Beaver County, Utah.

Fervo believes Cape Station can meet the needs of surging power demand from data centers, domestic manufacturing and an energy market aiming to use clean and reliable power. According to the company, Cape Station will begin delivering its first power to the grid this year and is expected to reach approximately 100 megwatts of operating capacity by early 2027. Fervo added that it plans to scale to 500 megawatts.

The $421 million financing package includes a $309 million construction-to-term loan, a $61 million tax credit bridge loan, and a $51 million letter of credit facility. The facilities will fund the remaining construction costs for the first phase of Cape Station, and will also support the project’s counterparty credit support requirements.

Coordinating lead arrangers include Barclays, BBVA, HSBC, MUFG, RBC and Société Générale, with additional participation from Bank of America, J.P. Morgan and Sumitomo Mitsui Trust Bank, Limited, New York Branch.

“As demand for firm, clean, affordable power accelerates, EGS (Enhanced Geothermal Systems) is set to become a core energy asset class for infrastructure lenders,” Sean Pollock, managing director, project Finance at RBC Capital Markets, said in a news release. “Fervo is pioneering this step change with Cape Station, a vital contribution to American energy security that RBC is proud to support.”

The oversubscribed financing marks Cape Station’s shift from early-stage and bridge funding to a long-term, non-recourse capital structure, according to the news release.

“Non-recourse financing has historically been considered out of reach for first-of-a-kind projects,” David Ulrey, CFO of Fervo Energy, said in a news release. “Cape Station disrupts that narrative. With proven oil and gas technology paired with AI-enabled drilling and exploration, robust commercial offtake, operational consistency, and an unrelenting focus on health and safety, we have shown that EGS is a highly bankable asset class.”

Fervo continues to be one of the top-funded startups in the Houston area. The company has raised about $1.5 billion prior to the latest $421 million. It also closed a $462 million Series E in December.

According to Axios Pro, Fervo filed for an IPO that would value the company between $2 billion and $3 billion in January.

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