ADVERTISEABOUT USSUBMIT A STORYSUBSCRIBETERMS OF USEPRIVACY POLICY
Visit our family of Brands

New Houston bioindustrial accelerator to spark biotech-based sustainability

supporting startups

The BioWell, founded by biotech investor First Bight Ventures, was established to support sustainability-focused bioindustrial startups. Photo via Getty Images

Bioindustrial technologies have a high potential for impacting sustainability — but they tend to need a little bit more help navigating the startup valley of death. That's where the BioWell comes in.

Carlos Estrada, head of Venture Acceleration at BioWell, says the idea for the accelerator was came to First Bight Ventures, a Houston-based biomanufacturing investment firm, as it began building its portfolio of promising companies.

"While we were looking at various companies, we found ourselves finding different needs that these startups have," Estrada says on the Houston Innovators Podcast. "That's how the opportunity for the BioWell came about."

Specifically, bioindustrial companies, which are tapping into life science innovation to create more sustainable products or services, need early funding, lab space, and strategic corporate partners to help research and develop their startups.

"The very direct challenge that we are seeing is that these companies very often have to spend their funds to build out their own lab spaces," Estrada says, "so by the time they're trying to focus back on the product itself, they are starting to run out of funding."

Carlos Estrada, head of Venture Acceleration at BioWell, joins the Houston Innovators Podcast to share why Houston is already a great hub for bioindustrial innovation. Photo courtesy of BioWell

BioWell is currently selecting its inaugural cohort and is also actively searching for its physical location to build out the program and facilities. Last year, BioWell secured $741,925 of the $53 million doled out as a part of the "Build to Scale" Grant program from the U.S. Economic Development Administration.

In addition to solving for specific challenges bioindustrial companies face, Estrada says the program will provide support for general startup and entrepreneurial guidance, like business plan development, navigating investors and grant funding, and more.

Just as First Bight Ventures was founded strategically in Houston to make the most of the local resources, the BioWell will operate out of the Bayou City — a market Estrada says has everything the industry needs.

"We have the right talent — our universities produce great researchers. We have the energy companies that are utilizing (a workforce) with transferable skills," he says on the show. "We also have the infrastructure, the square footage, and various real estate companies creating shells for lab space. We have the know how, the universities, and all at a lower cost, which plays a big role in the equation."

———

This article originally ran on InnovationMap.

Calling all biotechnology startups focusing on sustainable feedstocks, commercially viable yields, and purpose fit microbes. Photo via Getty Images

Houston organization rolls out new accelerator to support companies tackling 'pressing global challenges'

CALLING FOR APPLICANTS

A Houston organization — freshly funded by a $700,000 U.S. Economic Development Administration’s “Build to Scale” grant — is seeking its first accelerator cohort of industrial biology startups.

Founded by Houston-based First Bight Ventures, the BioWell has launched a virtual accelerator program that will provide programming, networking, mentorship, and financial resources to its inaugural cohort of 10 bioindustrial startups. The selected companies will also have access to specialized pilot bioproduction infrastructure throughout the nine-month program.

“BioWell equips startups with more than just capital. We provide a foundation for breakthrough innovations by combining access to cutting-edge bioproduction facilities with expertise that nurtures scalability. This comprehensive support is crucial for transforming pioneering ideas into market-ready solutions that can address pressing global challenges,” Carlos Estrada, head of venture acceleration at BioWell, says in a news release.

Applications for the program are open until May 15, and the cohort will be announced in June. Specifically, BioWell is seeking seed or pre-seed startup applicants that have a technology readiness level of 3 to 5, focusing on areas including low-cost and sustainable feedstocks, commercially viable yields, and purpose fit microbes.

“During our selection process, we'll prioritize startups that demonstrate a commitment to not only hitting milestones but also to building sustainable revenue streams for long-term survival. This phase necessitates keen awareness of market dynamics, customer demands, and sound financial management,” adds First Bight Ventures and BioWell Founder Veronica Wu.

In December, BioWell secured $741,925 of the $53 million doled out as a part of the "Build to Scale" Grant program that the U.S. Economic Development Administration, a division of the U.S. Department of Commerce, has established. First Bight was one of 60 organizations to receive funding.

Ex-Apple exec Wu founded First Bight Ventures in Houston in 2022 after relocating from Silicon Valley and seeing the region's potential for biotech.

------

This article originally ran on InnovationMap.

First Bight Venture's BioWell has received a $741,925 grant to continue supporting bioindustrial startups. Photo via Getty Images

Houston nonprofit accelerator receives grant funding to advance bioindustrial startups

the biowell

A Houston-based nonprofit accelerator that works with early-stage synthetic biology startups has secured nearly $750,000 to support its mission.

First Bight Ventures' accelerator, BioWell, secured $741,925 of the $53 million doled out as a part of the "Build to Scale" Grant program that the U.S. Economic Development Administration, a division of the U.S. Department of Commerce, has established. First Bight was one of 60 organizations to receive funding.

The funding will support the BioWell's mission to establish a "vibrant bioeconomy" by helping startups scale and commercialize "through access to a unique combination of pilot bioproduction infrastructure," according to a news release from First Bight.

"Startups at BioWell will gain access to a robust ecosystem, expertise, mentorship, and financial resources essential for successfully commercializing their bio-industrial innovations," BioWell Executive Director Paul Palmer says in the release.

The BioWell is still working toward establishing a physical space and has worked out of the East End Maker Hub in the meantime. The organization has partnered with Urban Partnerships Community Development Corporation, or UP CDC, which led the application process on this federal grant.

"BioWell chose to partner with UP CDC for the EDA grant, to continue the successful model that UP CDC has created at the East End Maker Hub for advanced manufacturing. UP CDC looks forward to continuing our partnership with BioWell in the UP CDC's BioCity project that will position Houston at the forefront of bio-manufacturing," UP CDC's CEO Patrick Ezzell says in the release.

First Bight Ventures Founder Veronica Wu established the BioWell to target high-potential startups, which usually have to overcome lack of funding challenges early on.

"Often times, early-stage startups gain momentum and hit important milestones, but ultimately find themselves heading toward the 'Valley of Death,' where progress is made on their enterprise, but no sufficient revenue is generated for the company's stability and longevity," Wu says in the release. "This 'Build to Scale' program's support will help offset these inevitable challenges in our bio-industrial space."

She shares more about her mission for First Bight Ventures on the Houston Innovators Podcast. Listen to the interview from March below.

———

This article originally ran on InnovationMap.

Greentown Houston has received funding from the EDA. Photo via GreentownLabs.com

Greentown Houston selected for federal program that's accelerating tech entrepreneurship

seeing green

Sixty organizations across the country have received a grant from the United States Department of Commerce — and one recipient is based in Houston.

Greentown Labs, dual located in Houston and Somerville, Massachusetts, has received a grant from the 10th cohort of the Economic Development Administration's “Build to Scale” program for its Houston location. The $53 million of funding was awarded to 60 organizations across 36 states, the District of Columbia, and Puerto Rico. All of the programs support technology entrepreneurs across industries.

“The Biden-Harris Administration is Investing in America to help create entrepreneurial ecosystems across the country and put quality, 21st century job opportunities in people’s backyards,” Secretary of Commerce Gina Raimondo says in the press release. “The ‘Build to Scale’ program will unlock innovation potential in regions all over the nation, improving our economic competitiveness now, and for decades to come.”

According to the EDA, Greentown, located in a growing innovation district, will receive $400,000 with a $400,000 local match confirmed. The project, named Houston Ion District Investor Activation, is described as a way to create economic opportunity through equitable capital access.

"This project capitalizes on the need for jobs and economic development, especially in communities most vulnerable to the impacts of natural disasters," reads the project abstract. "EDA funding will enable the expansion of Greentown’s Investor Program into EDIJ, in partnership with the Ion, to further climate equity and resilience in Houston and empower underrepresented entrepreneurs as the city transitions from fossil fuels to a clean energy economy."

Greentown receives of of the 2023 Capital Challenge Grant Recipients. The other competition, the Venture Challenge, also awarded funding to another Houston organization. The Urban Partnerships Community Development Corporation received $741,925 to support the BioWell Start Accelerator Program, which is committed to scaling of bio-industrial startups.

“EDA is proud to partner with this year’s ‘Build to Scale’ grantees as they fuel regional innovation hubs and technology-based economic development strategies throughout the U.S.,” Assistant Secretary of Commerce for Economic Development Alejandra Y. Castillo says in the release. “Investing in scalable startups and expanding access entrepreneurial capital will yield good-paying jobs, economic resiliency, and equitable growth in communities throughout America.”

Ad Placement 300x100
Ad Placement 300x600

CultureMap Emails are Awesome

Property Showcase

Energy co. to build 30 micro-nuclear reactors in Texas to meet rising demand

going nuclear

A Washington, D.C.-based developer of micro-nuclear technology plans to build 30 micro-nuclear reactors near Abilene to address the rising demand for electricity to operate data centers across Texas.

The company, Last Energy, is seeking permission from the Electric Reliability Council of Texas (ERCOT) and the U.S. Nuclear Regulatory Commission to build the microreactors on a more than 200-acre site in Haskell County, about 60 miles north of Abilene.

The privately financed microreactors are expected to go online within roughly two years. They would be connected to ERCOT’s power grid, which serves the bulk of Texas.

“Texas is America’s undisputed energy leader, but skyrocketing population growth and data center development is forcing policymakers, customers, and energy providers to embrace new technologies,” says Bret Kugelmass, founder and CEO of Last Energy.

“Nuclear power is the most effective way to meet Texas’ demand, but our solution—plug-and-play microreactors, designed for scalability and siting flexibility—is the best way to meet it quickly,” Kugelmass adds. “Texas is a state that recognizes energy is a precondition for prosperity, and Last Energy is excited to contribute to that mission.”

Texas is home to more than 340 data centers, according to Perceptive Power Infrastructure. These centers consume nearly 8 gigawatts of power and make up 9 percent of the state’s power demand.

Data centers are one of the most energy-intensive building types, says to the U.S. Department of Energy, and account for approximately 2 percent of the total U.S. electricity use.

Microreactors are 100 to 1,000 times smaller than conventional nuclear reactors, according to the Idaho National Laboratory. Yet each Last Energy microreactor can produce 20 megawatts of thermal energy.

Before announcing the 30 proposed microreactors to be located near Abilene, Last Energy built two full-scale prototypes in Texas in tandem with manufacturing partners. The company has also held demonstration events in Texas, including at CERAWeek 2024 in Houston. Last Energy, founded in 2019, is a founding member of the Texas Nuclear Alliance.

“Texas is the energy capital of America, and we are working to be No. 1 in advanced nuclear power,” Governor Greg Abbott said in a statement. “Last Energy’s microreactor project in Haskell County will help fulfill the state’s growing data center demand. Texas must become a national leader in advanced nuclear energy. By working together with industry leaders like Last Energy, we will usher in a nuclear power renaissance in the United States.”

Nuclear energy is not a major source of power in Texas. In 2023, the state’s two nuclear power plants generated about 7% of the state’s electricity, according to the U.S. Energy Information Administration. Texas gains most of its electricity from natural gas, coal, wind, and solar.

Tesla targets Houston area for $200 million 'mega' battery factory

Tesla Town

Tesla is expected to bring a “megafactory” and 1,500 manufacturing jobs to the Houston area.

According to various news reports this week, Tesla intends to spend $200 million on a facility in Brookshire, Texas. The Waller County Commissioners Court approved tax abatements on March 5 for the new plant.

“We are super excited about this opportunity—1,500 advanced manufacturing jobs in the county and in the city," Waller County Precinct 4 Commissioner Justin Beckendorff said during Wednesday’s Commissioners Court meeting.

Tesla will lease two buildings in Brookshire's Empire West Business Park. According to documents from Waller County, Tesla will add $44 million in facility improvements. In addition, it will install $150 million worth of manufacturing equipment.

As part of the deal, Tesla will invest in property improvements that involve a 600,000-square-foot, $31 million manufacturing facility that will house $2 million worth of equipment and include improvements to the venue.

The facility will produce Tesla megapacks, which are powerful batteries to provide energy storage and support, according to the company. A megapack can store enough energy to power about 3,600 homes for one hour.

Tesla can receive a 60 percent tax abatement for 10 years. According to the tax abatement agreement, Tesla has to employ at least 1,500 people by 2028 in order to be eligible for the tax break.

In addition to the employment clause, Tesla also will be required to have a minimum of $75 million in taxable inventory by January 1, 2026, which will increase to $300 million after three years.

---

This story originally appeared on our sister site, InnovationMap.

Here are 20+ CERAWeek 2025 events featuring Houston energy leaders

where to be

CERAWeek 2025 will host more than 1,400 speakers at its annual energy-focused conference taking place March 10-14, with many hailing from Houston.

Under this year's theme, "Moving Ahead: Energy strategies for a complex world,” panels will tackle topics ranging from policy and regulation, geopolitics, power, grid, and electrification, AI and digital, managing emissions, and more.

Most of the innovation-themed events are organized under the Agora track and will feature many Houston-area startups, universities, companies, and scientists. Here are all the events on the Agora track you can't miss if you want to learn more about Houston energy innovation.

Transition in Action: Energy giants shaping a sustainable future

ExxonMobil's Senior Director, Climate Strategy & Technology Vijay Swarup will examine how major energy companies are driving energy transition goals along with panelists from S&P Global, Aramco Ventures and Gentari Sdn Bhd.

This panel is from 12:30-1 p.m. on Monday, March 10. More info here.

Syzygy Plasmonics | Deploying the World’s Most Economic Biogas to SAF Technology

Hear from Syzygy Plasmonics CEO Trevor Best about how the cleantech company's catalyst and reactor work and how the tools can dramatically reduce the cost of producing SAF from biogas from landfills, wastewater, and dairy farms.

This panel is from 2-2:30 p.m. on Monday, March 10. More info here.

Cemvita | The Future of Bioengineered Feedstocks: A Foresight Perspective

Cemvita CEO Moji Karimi will lead this panel.

This panel is from 4:30-5:15 p.m. on Monday, March 10. More info here.

Innovating with Purpose: Strengthening industrial-academic partnerships

David Dankworth, ExxonMobil's Hydrogen Technology Portfolio Manager, and Brian Korgel, the University of Texas Energy Institute Director, will be joined by leaders from MIT and S&P Global to discuss the crucial relationship between universities and industry in fostering purpose-driven innovation.

This panel is from 8:30–9 a.m. on Tuesday, March 11. More info here.

Solidec | Low-cost, Low-carbon Chemicals from Air

Solidec co-founder and CEO Ryan DuChanois will discuss how the company's approach to producing hydrogen peroxide and other key chemicals can be low-cost and low-carbon, creating a scalable path for a more sustainable chemical industry.

This panel is from 9-9:30 a.m. on Tuesday, March 11. More information here.

Collaboration Spotlight: The Carbon Hub: A public-private partnership leading the way to a sustainable carbon economy

Panelists from Rice University, Huntsman Advanced Materials, CERAWeek, The Kavli Foundation, and SABIC will discuss Rice's Carbon Hub's transformative power and what the future looks like for those creating this new carbon economy. Matteo Pasquali, the founding Director of the Carbon Hub, will be featured on the panel.

This panel is from 9:30-10 a.m. on Tuesday, March 11. More information here.

Rice University | Next-generation Electrolyzers and Electrolysis

Haotian Wang, Associate Professor in the Department of Chemical and Biomolecular Engineering at Rice University and co-founder of Solidec, will discuss the development of next-generation electrolyzers that enable lower-cost and more energy-efficient carbon capture, chemical manufacturing and critical metal recovery.

This panel is from 9:30–10:15 a.m. on Tuesday, March 11. More information here.

ExxonMobil | Real-world Progress on Building a Low-carbon Business

Schuyler Evans, ExxonMobil's CCS commerical and business development manager low carbon solutions, will speak on how the energy giant is navigating a complex energy transition and share insights into the strategic thinking behind building a new business that helps reduce emissions.

This panel is from 10-10:30 a.m. on Tuesday, March 11. More information here.

Enovate.AI | AI-driven Advantage: Automate. Optimize. Decarbonize.

Enovate.AI Chief Experience Officer Rebecca Nye, joined by Last Mile Production, will show how its 3-clicks digital strategy empowers operators to make faster, smarter decisions—reducing emissions, enhancing productivity and unlocking new levels of profitability.

This panel is from 10:30–11 a.m. on Tuesday, March 11. More information here.

Financing the Future: Scaling clean energy through innovative investment strategies

Jim Gable, president of Chevron Technology Ventures and vice president of innovation, along with Greentown Lab's new CEO Georgina Campbell Flatter, will discuss the bankability of technologies in different geographies, investment opportunities in emerging markets, sources of funding and risk management strategies investors are using. Panelists also include leaders from Siemens Energy, Energy Impact Partners, and S&P Global Commodity Insights.

This panel is from 12:30–1:10 p.m. on Tuesday, March 11. More information here.

Sage Geosystems | Geothermal at the Speed of Need: How Sage Geosystems is meeting growing energy demand

Learn from Jason Peart, general manager of strategy and development, how Sage's approach to geothermal technology is tackling the fast-growing energy demands of critical sectors, including data centers, utilities, energy storage, and US Department of Defense projects.

This panel is from 1:30–2 p.m. on Tuesday, March 11. More information here.

Rice University | Valuing Nature-based Solutions for CO2 Removal

Carrie Masiello, director of the Rice Sustainability Institute, will introduce to the breadth of nature-based solutions possible, explore some of the most exciting opportunities and give guidance on how to think rigorously about matching individual NBS opportunities to specific portfolio needs.

This panel is from 1:30–2:15 p.m. on Tuesday, March 11. More information here.

Square Robot | Bridging the Divide: How Square Robot's tank inspections align corporate strategy with on-the-ground reality

Square Robot CEO David Lamont will discuss how companies can keep their tank assets online by adopting new technology and navigating the challenges of aligning corporate objectives with site-level realities.

This panel is from 3–3:30 p.m. on Tuesday, March 11. More information here.

The Green Gold Rush: A multi-trillion dollar opportunity?

Bobby Tutor, chairman of Houston Energy Transition Initiative and CEO of Artemis Energy Partners, will be joined by leaders from Accenture, S&P Global, and BeyondNetZero to discuss the immense economic potential of climate solutions and highlight the business opportunities created by the transition to a low-carbon economy.

This panel is from 4–4:30 p.m. on Tuesday, March 11. More information here.

ExxonMobil | Applying Technology to Maximize Value in the Permian Basin

James Ritchie, Exxon's vice president upstream technology portfolio, will share the latest technologies being developed and deployed to improve recovery and capital efficiency in the Permian Basin and demonstrate how these technologies and innovations maximize overall value while reducing greenhouse gas emissions and water usage.

This panel is from 2:30–3 p.m. on Wednesday, March 12. More information here.

Rice University | Plasma Foundry for Scalable Industrial Decarbonization

Aditya Mohite, a Rice professor and the faculty director of the Rice Engineering Initiative for Energy Transition and Sustainability (REINVENTS), will share how The Plasma Foundry, a 1:1 customized accelerator at Rice, is using cold plasma technology and its accelerator model to provide disruptive solutions at scale.

This panel is from 9:30–10:15 a.m. on Thursday, March 13. More information here.

Fervo Energy | Speed and Scale: The Geothermal Decade Is Now

Quinn Woodard Jr., Fervo Energy's senior director, power generation and surface facilities, will discuss how the company is pioneering transformative EGS technology to power data centers, homes and beyond.

This panel is from 10:30–11 a.m. on Thursday, March 13. More information here.

Corrolytics | Digitizing and Revolutionizing Corrosion Detection and Monitoring for Industrial Assets

Anwar Sadek, Corrolytics co-founder and CEO, will share how the company is revolutionizing corrosion detection and monitoring with patented technology to proactively enhance safety, reduce costs and extend asset lifespan.

This panel is from 10:30–11 a.m. on Thursday, March 13. More information here.

Zeta Energy | The Rise of Lithium-Sulfur Batteries: A solution to critical metal constraints

Rodrigo Salvatierra, Zeta's chief science officer, will introduce Zeta Energy’s lithium-sulfurized carbon technology, which effectively addresses the key limitations of lithium-sulfur batteries.

This panel is from 3–3:30 p.m. on Thursday, March 13. More information here.

Future Cities on the Move: Innovative pathways for sustainable urban mobility

Lisa Lin, Harris County's director of sustainability, will speak on this panel on successful public-private partnerships driving innovation in sustainable transport by leveraging technology and data analytics. She'll be joined by Aberdeen's council co-lead and leaders from S&P Global and GreenCap, based in Cape Town, South Africa.

This panel is from 3:30–4 p.m. on Thursday, March 13. More information here.

Collaboration Spotlight: Building a resilient Gulf Coast energy and chemical sector

Greater Houston Partnership and HETI's Jane Stricker will join Ramanan Krishnamoorti from the University of Houston and leaders from Argonne National Laboratory and SABIC to explore opportunities and pathways to strengthen the US Gulf Coast’s global leadership position in base chemical manufacturing and the national security and economic opportunities that innovation and process integration create.

This panel is from 4:30–5 p.m. on Thursday, March 13. More information here.

View All Listings