The BioWell, founded by biotech investor First Bight Ventures, was established to support sustainability-focused bioindustrial startups. Photo via Getty Images

Bioindustrial technologies have a high potential for impacting sustainability — but they tend to need a little bit more help navigating the startup valley of death. That's where the BioWell comes in.

Carlos Estrada, head of Venture Acceleration at BioWell, says the idea for the accelerator was came to First Bight Ventures, a Houston-based biomanufacturing investment firm, as it began building its portfolio of promising companies.

"While we were looking at various companies, we found ourselves finding different needs that these startups have," Estrada says on the Houston Innovators Podcast. "That's how the opportunity for the BioWell came about."

Specifically, bioindustrial companies, which are tapping into life science innovation to create more sustainable products or services, need early funding, lab space, and strategic corporate partners to help research and develop their startups.

"The very direct challenge that we are seeing is that these companies very often have to spend their funds to build out their own lab spaces," Estrada says, "so by the time they're trying to focus back on the product itself, they are starting to run out of funding."

Carlos Estrada, head of Venture Acceleration at BioWell, joins the Houston Innovators Podcast to share why Houston is already a great hub for bioindustrial innovation. Photo courtesy of BioWell

BioWell is currently selecting its inaugural cohort and is also actively searching for its physical location to build out the program and facilities. Last year, BioWell secured $741,925 of the $53 million doled out as a part of the "Build to Scale" Grant program from the U.S. Economic Development Administration.

In addition to solving for specific challenges bioindustrial companies face, Estrada says the program will provide support for general startup and entrepreneurial guidance, like business plan development, navigating investors and grant funding, and more.

Just as First Bight Ventures was founded strategically in Houston to make the most of the local resources, the BioWell will operate out of the Bayou City — a market Estrada says has everything the industry needs.

"We have the right talent — our universities produce great researchers. We have the energy companies that are utilizing (a workforce) with transferable skills," he says on the show. "We also have the infrastructure, the square footage, and various real estate companies creating shells for lab space. We have the know how, the universities, and all at a lower cost, which plays a big role in the equation."

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This article originally ran on InnovationMap.

Calling all biotechnology startups focusing on sustainable feedstocks, commercially viable yields, and purpose fit microbes. Photo via Getty Images

Houston organization rolls out new accelerator to support companies tackling 'pressing global challenges'

CALLING FOR APPLICANTS

A Houston organization — freshly funded by a $700,000 U.S. Economic Development Administration’s “Build to Scale” grant — is seeking its first accelerator cohort of industrial biology startups.

Founded by Houston-based First Bight Ventures, the BioWell has launched a virtual accelerator program that will provide programming, networking, mentorship, and financial resources to its inaugural cohort of 10 bioindustrial startups. The selected companies will also have access to specialized pilot bioproduction infrastructure throughout the nine-month program.

“BioWell equips startups with more than just capital. We provide a foundation for breakthrough innovations by combining access to cutting-edge bioproduction facilities with expertise that nurtures scalability. This comprehensive support is crucial for transforming pioneering ideas into market-ready solutions that can address pressing global challenges,” Carlos Estrada, head of venture acceleration at BioWell, says in a news release.

Applications for the program are open until May 15, and the cohort will be announced in June. Specifically, BioWell is seeking seed or pre-seed startup applicants that have a technology readiness level of 3 to 5, focusing on areas including low-cost and sustainable feedstocks, commercially viable yields, and purpose fit microbes.

“During our selection process, we'll prioritize startups that demonstrate a commitment to not only hitting milestones but also to building sustainable revenue streams for long-term survival. This phase necessitates keen awareness of market dynamics, customer demands, and sound financial management,” adds First Bight Ventures and BioWell Founder Veronica Wu.

In December, BioWell secured $741,925 of the $53 million doled out as a part of the "Build to Scale" Grant program that the U.S. Economic Development Administration, a division of the U.S. Department of Commerce, has established. First Bight was one of 60 organizations to receive funding.

Ex-Apple exec Wu founded First Bight Ventures in Houston in 2022 after relocating from Silicon Valley and seeing the region's potential for biotech.

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This article originally ran on InnovationMap.

First Bight Venture's BioWell has received a $741,925 grant to continue supporting bioindustrial startups. Photo via Getty Images

Houston nonprofit accelerator receives grant funding to advance bioindustrial startups

the biowell

A Houston-based nonprofit accelerator that works with early-stage synthetic biology startups has secured nearly $750,000 to support its mission.

First Bight Ventures' accelerator, BioWell, secured $741,925 of the $53 million doled out as a part of the "Build to Scale" Grant program that the U.S. Economic Development Administration, a division of the U.S. Department of Commerce, has established. First Bight was one of 60 organizations to receive funding.

The funding will support the BioWell's mission to establish a "vibrant bioeconomy" by helping startups scale and commercialize "through access to a unique combination of pilot bioproduction infrastructure," according to a news release from First Bight.

"Startups at BioWell will gain access to a robust ecosystem, expertise, mentorship, and financial resources essential for successfully commercializing their bio-industrial innovations," BioWell Executive Director Paul Palmer says in the release.

The BioWell is still working toward establishing a physical space and has worked out of the East End Maker Hub in the meantime. The organization has partnered with Urban Partnerships Community Development Corporation, or UP CDC, which led the application process on this federal grant.

"BioWell chose to partner with UP CDC for the EDA grant, to continue the successful model that UP CDC has created at the East End Maker Hub for advanced manufacturing. UP CDC looks forward to continuing our partnership with BioWell in the UP CDC's BioCity project that will position Houston at the forefront of bio-manufacturing," UP CDC's CEO Patrick Ezzell says in the release.

First Bight Ventures Founder Veronica Wu established the BioWell to target high-potential startups, which usually have to overcome lack of funding challenges early on.

"Often times, early-stage startups gain momentum and hit important milestones, but ultimately find themselves heading toward the 'Valley of Death,' where progress is made on their enterprise, but no sufficient revenue is generated for the company's stability and longevity," Wu says in the release. "This 'Build to Scale' program's support will help offset these inevitable challenges in our bio-industrial space."

She shares more about her mission for First Bight Ventures on the Houston Innovators Podcast. Listen to the interview from March below.

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This article originally ran on InnovationMap.

Greentown Houston has received funding from the EDA. Photo via GreentownLabs.com

Greentown Houston selected for federal program that's accelerating tech entrepreneurship

seeing green

Sixty organizations across the country have received a grant from the United States Department of Commerce — and one recipient is based in Houston.

Greentown Labs, dual located in Houston and Somerville, Massachusetts, has received a grant from the 10th cohort of the Economic Development Administration's “Build to Scale” program for its Houston location. The $53 million of funding was awarded to 60 organizations across 36 states, the District of Columbia, and Puerto Rico. All of the programs support technology entrepreneurs across industries.

“The Biden-Harris Administration is Investing in America to help create entrepreneurial ecosystems across the country and put quality, 21st century job opportunities in people’s backyards,” Secretary of Commerce Gina Raimondo says in the press release. “The ‘Build to Scale’ program will unlock innovation potential in regions all over the nation, improving our economic competitiveness now, and for decades to come.”

According to the EDA, Greentown, located in a growing innovation district, will receive $400,000 with a $400,000 local match confirmed. The project, named Houston Ion District Investor Activation, is described as a way to create economic opportunity through equitable capital access.

"This project capitalizes on the need for jobs and economic development, especially in communities most vulnerable to the impacts of natural disasters," reads the project abstract. "EDA funding will enable the expansion of Greentown’s Investor Program into EDIJ, in partnership with the Ion, to further climate equity and resilience in Houston and empower underrepresented entrepreneurs as the city transitions from fossil fuels to a clean energy economy."

Greentown receives of of the 2023 Capital Challenge Grant Recipients. The other competition, the Venture Challenge, also awarded funding to another Houston organization. The Urban Partnerships Community Development Corporation received $741,925 to support the BioWell Start Accelerator Program, which is committed to scaling of bio-industrial startups.

“EDA is proud to partner with this year’s ‘Build to Scale’ grantees as they fuel regional innovation hubs and technology-based economic development strategies throughout the U.S.,” Assistant Secretary of Commerce for Economic Development Alejandra Y. Castillo says in the release. “Investing in scalable startups and expanding access entrepreneurial capital will yield good-paying jobs, economic resiliency, and equitable growth in communities throughout America.”

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Houston clean energy storage facility goes online to power ERCOT grid

green light

A new battery energy storage facility in Houston is officially up and running to power the ERCOT grid with a supply of reliable, zero emissions power.

Jupiter Power announced the commercial operations launch of its 400-megawatt-hour battery facility, Callisto I, in central Houston on the site of the former HL&P H.O. Clarke fossil fuel power plant.

"Jupiter couldn't be prouder about bringing the Callisto I project online," Andy Bowman, CEO of Jupiter Power, says in a news release. "This project responds to lawmakers' calls to increase affordable and dispatchable new generation in an area where people need more power. Callisto I is the first energy storage project at this scale in the City of Houston and will help meet Houston's growing power needs while also increasing resiliency from extreme weather events."

The new project is Jupiter Power's ninth project to deliver energy storage to ERCOT — bringing its total ERCOT fleet to 1,375-megawatt-hour capacity — but its the first in the Houston area. The company is currently developing over 11,000 megawatts of projects across the country. Founded in 2017, Jupiter Power is headquartered in Austin and has offices in Houston and Chicago.

"The announcement of Jupiter Power's Callisto I Energy Storage project is significant and exciting for the region, as it's the first large-scale transmission-connected energy storage project in the City of Houston," Jane Stricker, senior vice president at the Greater Houston Partnership and executive director at the Houston Energy Transition Initiative, adds. "This critical project will help address peak power demand and is another great example of our region's leadership in scaling and deploying impactful solutions for an all the above energy future."

Among the company's financial backers is Houston-based EnCap Energy Transition, which invested in Jupiter Power via its Fund II.

Japanese agency invests $36M into Houston e-fuels company's portfolio

coming in hot

Houston-based electrofuel company HIF Global has secured a $36 million investment from the Japan Organization for Metals and Energy Security, a government agency.

The investment, made through an e-fuel subsidiary of Japanese energy company Idemitsu Kosan, is earmarked for HIF’s e-fuel projects in the U.S., Australia, Chile, and Uruguay.

Earlier this year, Idemitsu led a $164 million investment round in HIF. Of that amount, Idemitsu chipped in $114 million. Other investors included Houston-based Baker Hughes along with AME, EIG, Gemstone Investments, and Porsche.

In total, HIF has raised $200 million this year.

“Japan set a priority for the commercial introduction of e-fuels into its fuel supply to support their mandate for 46 percent [greenhouse gas] emissions reduction by 2030. We have already proven e-fuels are a real solution with over 18 months of e-fuels production from our Haru Oni facility in southern Chile,” says Cesar Norton, president and CEO of HIF.

In 2023, Idemitsu agreed to buy e-methanol from HIF’s $6 billion plant in Matagorda County. HIF says the plant will be the world’s first large-scale e-fuel facility. The plant is expected to produce about 1.4 million metric tons per year of e-methanol and about 300,000 metric tons of green hydrogen per year by 2027.

HIF, founded in 2016, aims to produce 150,000 barrels per day of e-fuel and recycle 25 million metric tons per year of carbon dioxide by 2035. E-fuels, which are synthetic alternatives to fossil fuels, include e-gasoline, e-diesel, and e-sustainable aviation fuel converted from e-methanol.

Using electrolyzers powered by renewable energy, HIF begins the e-fuel process by separating hydrogen from oxygen in water. The company then couples the resulting green hydrogen with recycled carbon dioxide to create carbon-neutral e-fuels.

Law firm expands energy team in Houston with addition of 2 transaction attorneys

new hires

Two lawyers have joined Winston & Strawn's energy practice in Houston.

Kevin Brophy and Ming Lei were named as partners and members of the firm's transactions department.

“Kevin and Ming’s extensive experience executing all manner of sophisticated transactions for energy and infrastructure clients combined with their strong networks in the energy sector enhance Winston’s position in Texas as one of the strongest firms for handling these transactions,” Mike Blankenship, Houston office managing partner, says in a news release. “Their complementary skills will help expand our work with private equity firms and other companies operating in the energy sector.”

Brophy's focus includes upstream and midstream sectors, and Lei advises clients on energy transition, as well as oil and gas exploration, storage, refinery, and more. Both have expertise in mergers and acquisitions, joint ventures, asset acquisitions and dispositions, and more.

“Winston’s transactions team has a first-class reputation. We are excited to join the firm’s growing Houston office and look forward to collaborating with our new colleagues to advance Winston’s oil and gas practice in Texas and beyond,” Brophy and Lei say in a joint statement.