Four Houston scientists have been awarded funding through the Department of Energy's Genesis Mission. Photos courtesy

The U.S. Department of Energy has named the nearly 300 projects selected under the Trump Administration's Genesis Mission, which aims to address some of the largest science and technology challenges in the country. The group features four projects from Houston universities and companies.

The initiative aims to unite government, industry, academia and philanthropy to lead to breakthroughs in energy, scientific discovery and national security, according to a release.

The selected projects feature 87 led by DOE and National Nuclear Security Administration (NNSA) National Laboratories, 168 led by universities, 19 led by companies and 4 led by nonprofit organizations—totalling 342 participating institutions.

“America has no shortage of bold ideas or talented scientists, and the response to the Genesis Mission proves that,” U.S. Secretary of Energy Chris Wright said in a news release. “The 278 projects selected today represent the very best of our nation’s scientific enterprise. The remarkable number of high-quality proposals we received demonstrates that America’s innovation pipeline is strong, and it points to even greater opportunities for future investment and continued expansion of the Genesis Mission portfolio.”

Twelve Texas-based projects were selected among the 278. The Houston projects and their researchers include:

Caroline Ajo-Franklin

Ajo-Franklin recieved a Phase I grant for her project "Predictive AI to Map Point Mutation Effects on Protein Function: Measurement and Biosynthesis of Isoprenoids." Ajo-Franklin is a professor of biosciences at Rice University, a CPRIT Scholar in Cancer Research and member of the Rice Synthetic Biology Institute. The project aims to accelerate the engineering of microbes that can produce isoprenoids, which are natural compounds that could replace petroleum-derived fuels, solvents and materials.

“This project creates a continuous feedback loop in which AI guides experiments and each experiment generates more detailed data to better hone the AI model,” Ajo-Franklin said in a news release. “In addition, it demonstrates the extraordinary star power Rice has recruited in protein engineering and synthetic biology.”

Anastasios Kyrillidis

Kyrillidis recived a Phase I grant for his project "Cracking the VQA Optimization Bottleneck: AI Methods for Quantum Chemistry and Materials." Kyrillidis is the Noah Harding Associate Professor of Computer Science at Rice and a member of the Ken Kennedy Institute. The project aims to develop AI tools to resolve bottlenecks in quantum computing for chemistry and materials research.

“Our goal is to replace fragile, hand-tuned optimization methods with intelligent systems that can learn from quantum computations while still operating within frameworks that provide strong mathematical guarantees,” Kyrillidis added in the release.

Myoungkyu Lee

Lee received a nearly $750,000 Phase I grant for his project "Physics-Informed AI Surrogates for Turbulent Forced Convection in Energy System." Lee is an assistant professor of mechanical aerospace engineering at the University of Houston. Lee will collaborate with researchers from Lawrence Livermore National Laboratory and University of Pennsylvania on the project and develop artificial intelligence to accelerate the design of materials for advanced nuclear fission and fusion reactors.

“The goal is to develop a tool that runs much faster than today’s most detailed simulations while keeping errors small,” Lee said in a news release. “If successful, the approach could support better heat-transfer predictions for molten-salt reactor design and provide a starting point for studying heat removal in fusion blankets. This is one contribution among many toward reliable, carbon-free energy.”

Amit Padhi

Padhi recieved a grant for his project "Probabilistic Inference of Subsurface Fracture Connectivity for Stimulation Control with Physics-Informed AI." Padhi is a scientific advisor for Halliburton.

The DOE first called for applications for the Genesis Mission in March. At the time, the DOE shared that it would grant approximately $293 million to the selected teams via Phase I awards, ranging from $500,000 to $750,000 for nine-month project periods, and Phase II awards, for $6 million to $15 million over a three-year project period.

Since then, however, the initiative has grown with 15 federal agencies now granting research awards and funding opportunities under the Genesis umbrella. The White House announced this week that it had secured more than $5 billion in federal commitments to expand the initiative.

Ad Placement 300x100
Ad Placement 300x600

CultureMap Emails are Awesome

ExxonMobil expands Gulf Coast CCS business with Louisiana deal

carbon contract

Spring-based energy powerhouse ExxonMobil has picked up another project in the carbon capture and storage (CCS) market.

Natural gas pipeline operator Williams Cos. has tapped ExxonMobil to transport and store up to one metric ton per year of CO2 from Williams’ natural gas collection and processing plant in southwest Louisiana’s Haynesville Shale.

Williams will transport natural gas via its Louisiana Energy Gateway pipeline, then process the natural gas and deliver it to the Gulf Coast for export as liquefied natural gas (LNG). The LNG will be used in power generation, residential and commercial heating, and industrial processes.

Williams recently agreed to acquire Momentum Midstream for up to $5.5 billion to expand Williams’ LNG presence in the Haynesville Shale. Haynesville is the country’s third-largest producer of natural gas.

Once the deal closes, Williams will own a $1.5 billion project in southwest Louisiana that will expand capacity of the Transco natural gas distribution system. The system serves power and LNG-export customers. Williams will also gain over 4,000 miles of pipeline and more than one million acres.

While Williams is based in Tulsa, Oklahoma, it has a significant presence in Houston. Last month, Green Street’s Real Estate Alert reported Williams bought the 64-story, 1.4 million-square-foot Williams Tower south of The Galleria from Invesco Real Estate for more than $300 million. The company will occupy about 360,000 square feet in the skyscraper for its Houston hub.

Williams employs about 800 people in Bayou City, including roughly 700 who work at Williams Tower, and plans to hire another 100 by the end of this year.

The Williams deal is ExxonMobil’s seventh CCS contract. ExxonMobil’s CCS portfolio supports LNG, lower-carbon-intensity steel, ammonia, natural gas processing, industrial gases and methanol.

ExxonMobil has established a “carbon superhighway” along the Gulf Coast to fuel its CCS business. The company owns and operates a more than 1,300-mile CO2 pipeline system, the largest in the U.S.

“Carbon capture is becoming an increasingly important part of industrial operations, but capture alone doesn’t solve the problem of high emissions,” says ExxonMobil. “What matters next is how CO2 is transported, used, and stored.”

ExxonMobil’s CCS initiatives are aimed at capturing a chunk of the rapidly growing CCS market in the U.S. Straits Research forecasts the market will grow from $5.66 billion this year to $13.56 billion by 2034.

“It’s not every day you get to witness the birth of a new American industry, but that’s exactly what’s happening right now at the U.S. Gulf Coast,” Dominic Genetti, senior vice president of CCS at ExxonMobil, wrote in an article published last year on the company’s website.

Fervo Energy, Mercury Fund leaders named first experts in residence for TEX-E

energy mentors

Two leading companies in Houston's clean energy scene have been named the Texas Exchange for Energy & Climate Entrepreneurship's first experts in residence.

TEX-E announced this month that Houston-based geothermal unicorn Fervo Energy and venture capital firm Mercury Fund have joined the nonprofit's new Expert-in-Residence partnership. The program aims to connect TEX-E Fellows with "the people and organizations shaping the future of energy and entrepreneurship."

The 2026 TEX-E Fellows were named in June and include 67 students from six Texas universities and the Massachusetts Institute of Technology. Nineteen are from Houston universities. See the full list here.

Through the Expert-in-Residence program, fellows will be able to network and work with:

"More than anything, students need the determination and creativity to step outside of their comfort zones and tackle problems that lack clear answers. At Fervo, we've consistently bet on young people who lack traditional 'hard skills' but are willing to embrace uncertainty and learn on the job. That open-mindedness will take students far," Jewett said in a prepared statement. Fervo named Jewett as COO in June.

TEX-E was founded in 2022 through partnerships with MIT Martin Trust Center for Entrepreneurship and Greentown Labs. It works with university students from six schools: Rice University, University of Houston, Prairie View A&M University, The University of Texas at Austin, Texas A&M University and MIT.

The organization named Houston venture capital and innovation leader Sandy Guitar as its new executive director last year. Guitar previously served as general partner and managing director at Houston-based VC firm HX Venture Fund and is co-founder of Weathergage Capital.

TEX-E is known for its student track within the Energy Venture Day and Pitch Competition at CERAWeek. It awarded $50,000 to student teams from the University of Texas and Rice University. Read more here.