Solugen claims a spot on CNBC’s annual Disruptor 50 list, which highlights private companies that are “upending the classic definition of disruption.” Photo via solugen.com

Houston-based biotech startup Solugen is making waves among innovative companies.

Solugen appears at No. 36 on CNBC’s annual Disruptor 50 list, which highlights private companies that are “upending the classic definition of disruption.” Privately owned startups founded after January 1, 2009, were eligible for the Disruptor 50 list.

Founded in 2016, Solugen replaces petroleum-based products with plant-derived substitutes through its Bioforge manufacturing platform. For example, it uses engineered enzymes and metal catalysts to convert feedstocks like sugar into chemicals that have traditionally been made from fossil fuels, such as petroleum and natural gas.

Solugen has raised $643 million in funding and now boasts a valuation of $2.2 billion.

“Sparked by a chance medical school poker game conversation in 2016, Solugen evolved from prototype to physical asset in five years, and production hit commercial scale shortly thereafter,” says CNBC.

Solugen co-founders Gaurab Chakrabarti and Sean Hunt received the Entrepreneur of The Year 2023 National Award, presented by professional services giant EY.

“Solugen is a textbook startup launched by two partners with $10,000 in seed money that is revolutionizing the chemical refining industry. The innovation-driven company is tackling impactful, life-changing issues important to the planet,” Entrepreneur of The Year judges wrote.

In April 2024, Solugen broke ground on a Bioforge biomanufacturing plant in Marshall, Minnesota. The 500,000-square-foot, 34-acre facility arose through a Solugen partnership with ADM. Chicago-based ADM produces agricultural products, commodities, and ingredients. The plant is expected to open in the fall of 2025.

“Solugen’s … technology is a transformative force in sustainable chemical manufacturing,” says Hunt. “The new facility will significantly increase our existing capabilities, enabling us to expand the market share of low-carbon chemistries.”

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This article originally ran on InnovationMap.

Gaurab Chakrabarti and Sean Hunt were originally named regional winners in this year's competition this summer along with nine other Houston entrepreneurs. Photos via solugen.com

Houston sustainability startup founders named winners for 2023 Entrepreneur of the Year awards

winner, winner

Houston’s Gaurab Chakrabarti and Sean Hunt, the founders of the transformative chemical manufacturing company Solugen, have been named EY’s US National Award winners for Entrepreneur of the Year.

Solugen, also recently named a finalist in the 2023 Houston Innovation Awards, is an environmentally friendly approach that relies on smaller chemical refineries that helps in reducing costs and transportation-related emissions.

Some of their noted accomplishments includes innovations like the proprietary reactor, dubbed the Bioforge, which is a carbon-negative molecule factory and manufacturing process produces zero wastewater or emissions compared with traditional petrochemical refineries.The Bioforge uses a chemienzymatic process in converting plant-sourced substances into essential materials that can be used instead of fossil fuels.

Chakrabarti and Hunt were originally named regional winners in this year's competition this summer along with nine other Houston entrepreneurs.

Founded in 2016 by Hunt and Gaurab Chakrabarti, Solugen has raised over $600 million from investors like Sasol that believe in the technology's potential. The company is valued at reportedly over $2 billion. Solugen is headquartered in Houston, not because it is the hometown of Chakrabarti, but for what Houston brings to the company.

“There’s no way our business could succeed in the Bay Area," Chakrabarti said in a 2023 interview at SXSW where he detailed the offers Hunt and he received to move the business out of state. “For our business, if you look at the density of chemical engineers, the density of our potential customers, and the density of people who know how to do enzyme engineering, Houston happened to be that perfect trifecta for us.”

Even though they are headquartered in Houston, Solugen recently secured plans to expand to the Midwest, as in November they announced its newest strategic partnership with sustainable solutions company ADM (NYSE:ADM) in Marshall, Minnesota. The partnership includes plans for Solugen to build a 500,000-square-foot biomanufacturing facility next to an existing ADM facility , with the two companies working together on producing biomaterials to replace fossil fuel products.

“The strategic partnership with ADM will allow Solugen to bring our chemienzymatic process to a commercial scale and meet existing customer demand for our high-performance, cost-competitive, sustainable products,” Chakrabarti said in a news release. “As one of the few scaled-up and de-risked biomanufacturing assets in the country, Solugen’s Bioforge platform is helping bolster domestic capabilities and supply chains that are critical in ensuring the U.S. reaches its ambitious climate targets.”

For Chakrabarti and Hunt, Solugen was born out of a 12-year friendship, and the journey began after a friendly card game. After an entrepreneurship contest at MIT, which earned them second place and a $10,000 prize, they invested the winnings to work on what would become Solugen, a proof-of-concept reactor with materials bought from a local home improvement store.

"We had a conviction that we were building something that could be impactful to the rest of the world,” Chakrabarti said at SXSW in 2023.

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This article originally ran on InnovationMap.

Houston-based Solugen will build a 500,000-square-foot biomanufacturing facility in the Midwest thanks to a new strategic partnership.

Houston-based sustainable chemicals co. to build ​Midwest biomanufacturing facility

it's corn

Solugen has scored a partnership with a global company to build a biomanufacturing facility adjacent to an existing corn complex in Marshall, Minnesota.

Solugen, a Houston company that's designed a process that converts plant-derived substances into essential materials, has announced its newest strategic partnership with sustainable solutions company ADM (NYSE:ADM). The partnership includes plans for Solugen to build a 500,000-square-foot biomanufacturing facility next to an existing ADM facility in the Midwest. The two companies will collaborate on producing biomaterials to replace fossil fuel-based products.

“The strategic partnership with ADM will allow Solugen to bring our chemienzymatic process to a commercial scale and meet existing customer demand for our high-performance, cost-competitive, sustainable products,” Gaurab Chakrabarti, co-founder and CEO of Solugen, says in a news release. “As one of the few scaled-up and de-risked biomanufacturing assets in the country, Solugen’s Bioforge platform is helping bolster domestic capabilities and supply chains that are critical in ensuring the U.S. reaches its ambitious climate targets.”

The company plans to begin on-site construction early next year, with plans to startup in the first half of 2025. The project should create at least 40 permanent jobs and 100 temporary construction positions.

“Sustainability is one of the enduring global trends powering ADM’s growth and underpinning the strategic evolution of our Carbohydrate Solutions business,” Chris Cuddy, president of ADM’s Carbohydrate Solutions business, says in the release. “ADM is one of the largest dextrose producers in the world, and this strategic partnership will allow us to further diversify our product stream as we continue to support plant-based solutions spanning sustainable packaging, pharma, plant health, construction, fermentation, and home and personal care.”

Founded in 2016 by Chakrabarti and Sean Hunt, Solugen's carbon-negative molecule factory, named the Bioforge, uses its chemienzymatic process in converting plant-sourced substances into essential materials that can be used instead of fossil fuels. The manufacturing process is carbon neutral, and Solugen has raised over $600 million from investors that believe in the technology's potential.

“The initial phase of the project will significantly increase Solugen’s manufacturing capacity, which is critical for commercializing our existing line of molecules and kicks off plans for a multi-phase large-scale U.S. Bioforge buildout,” Hunt, CTO of Solugen, says in the release. “The increase in capacity will also free up our Houston operation for research and development efforts into additional molecules and market applications.”

The project should create at least 40 permanent jobs and 100 temporary construction positions.

"As a community with a strong foundation of agriculture and innovation, we look forward to welcoming Solugen to Marshall. This industry-leading facility will serve as a powerful economic driver for the city, creating new jobs and diversifying our industry,” City of Marshall Mayor Bob Byrnes says in the statement. "We are thankful for ADM’s longstanding commitment and impact to Marshall, which has paved the way for this remarkable partnership and continues to further economic growth to our region."

It's the second major company partnership announcement Solugen has made this month, with a new arrangement with Sasol being secured last week.

Solugen and Sasol have entered into a strategic partnership. Photo via Solugen

Houston-based sustainable chemicals company secures major partnership with Sasol

cleaner chemicals

A Houston company that's creating cleaner chemicals with little to no impact on the environment has scored a partnership with a major chemicals producer.

Solugen and Sasol Chemicals, a business unit of Saslo Ltd., revealed that they are working together to explore commercialization of sustainably-made home and personal care products.

“This agreement is an example of our approach of partnering to find innovative solutions for our customers,” Jonathan Ward, senior manager of Strategy and Sustainable Growth for Sasol’s Essential Care Chemicals business division, says in a news release. “Our focus is delivering high-performing products with lower carbon footprints at competitive prices, and we are eager to see how Solugen’s products might help us do that.”

Founded in 2016 by Sean Hunt and Gaurab Chakrabarti, Solugen's carbon-negative molecule factory, named the Bioforge, uses a chemienzymatic process in converting plant-sourced substances into essential materials that can be used instead of fossil fuels. The manufacturing process is carbon neutral, and Solugen has raised over $600 million from investors that believe in the technology's potential.

"We are thrilled to partner with Sasol Chemicals, one of the world’s largest producers of surfactants, to drive positive impact in the home and personal care market,” Chakrabarti, CEO of Solugen, says in the release. “Sasol’s commitment to sustainability makes it an ideal partner for Solugen. We look forward to leveraging our combined strengths in technology, production, and market development to meet increasing consumer demand for our high-performance, bio-based solutions.”

Chakrabarti shared some of the secrets to Solugen's success and early partnerships at a SXSW panel earlier this year. The company was also recently named a finalist in the 2023 Houston Innovation Awards.

These Houston-area executives were recognized by EY's annual regional awards. Photos courtesy

Houston energy leaders score wins at annual regional entrepreneur competition

eyes on EY

You might say that four Houston executives with ties to the energy sector are energized about an award they just received.

The four executives recently were named winners in the Gulf South division of the Entrepreneur Of The Year awards program. They’ll now compete at the national level.

The one winner who works directly in the energy industry is Roger Jenkins, president and CEO of Houston-based Murphy Oil. Jenkins rose to the company’s top positions in 2013. He joined Murphy Oil in 2001 as a drilling manager in Malaysia.

Jenkins earned a bachelor’s degree in petroleum engineering from Louisiana State University and an MBA from Harvard University’s business school.

Murphy Oil is an oil and natural gas exploration and production company that operates primarily onshore in the U.S. and Canada, and offshore in the Gulf of Mexico.

A Fortune 1000 company founded in 1944, Murphy Oil generated revenue of nearly $4 billion in 2022.

In 2020, the company announced it was shuttering its headquarters in El Dorado, Arkansas, as well as its location in Calgary, Canada, and consolidating its operations into a new main office in Houston. About 190 Murphy Oil employees worked in El Dorado and Calgary.

“Our ongoing execution excellence across our significant offshore backlog and over 1,000 oil-weighted onshore locations will ensure that we will remain a long-term sustainable company,” Jenkins told Wall Street analysts in May 2023.

While not exactly an energy company, Solugen's co-founders — Gaurab Chakrabarti, CEO, and Sean Hunt, CTO — are representing the clean chemicals space within the energy transition.

Solugen, founded in 2016, makes and distributes specialty chemicals derived from feedstock. The startup is reportedly valued at more than $2 billion. To date, Solugen has raised $642.2 million, according to Crunchbase.

In naming Solugen one of the most innovative companies of 2022, Fast Company noted that the carbon-negative process embraced by Solugen and the startup’s “ability to sell flexible amounts of chemicals to companies looking to lower their own footprint have helped the company make inroads in a traditionally slow-moving industry.”

Another Houston executive with connections to the energy sector also is regional Entrepreneur Of The Year winners.

Ludmila Golovine is president and CEO of Houston-based MasterWord Services. The company provides translation and interpretation services in more than 400 languages for clients in sectors like energy, health care, and tech. The woman-owned business launched in 1993.

“It is a great honor for me and for MasterWord to be recognized alongside the other EY Entrepreneur Of The Year winners,” Golovine says in a news release about the Entrepreneur Of The Year honor.

In all, 10 executives from Houston-based companies were hailed as 2023 regional winners in the Entrepreneur Of The Year program, run by professional services firm EY. Aside from Jenkins, Golovine, Walker, and Smith, they are:

  • Steve Altemus, president and CEO of space exploration company Intuitive Machines.
  • Mark Walker, co-founder, chairman and CEO of Houston-based Direct Digital Holdings, and Keith Smith, co-founder and president. Direct Digital Holdings operates advertising platforms for clients in sectors such as energy, health care, travel and financial services.
  • Daryl Dudum and Matthew Hadda, founders and co-CEOs of Specialty1 Partners. The company provides business services to dental surgery practices.
  • Mohammad Millwala, founder and CEO of DM Clinical Research. The company operates 13 sites for clinical trials.

Also grabbing a regional award is Omair Tariq, co-founder and CEO of Austin-based Cart.com. The company, which provides software and services to online merchants, relocated its headquarters from Houston to Austin in 2021. Tariq remains in Houston, though.

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Chevron eyes $7B Texas power plant for Microsoft data center campus

power deal

Software giant Microsoft is negotiating exclusively with Houston-based oil and gas titan Chevron and investment firm Engine No. 1 about the development of a $7 billion power plant in West Texas that would supply electricity for a Microsoft data center campus.

The proposed natural-gas-fired plant initially would generate 2,500 megawatts of electricity, Bloomberg reports. The plant would be built near Pecos, a Permian Basin city, in an area where Microsoft plans to build a 2,500-megawatt data center campus on a 7,000-acre site.

A deal with Microsoft would secure a long-term customer for the plant’s output and help finance its construction, Bloomberg says. The project, expected to be producing power by 2030, still requires tax and environmental approvals as well an agreement to terms among Chevron, Engine No. 1, and Microsoft.

In a statement issued after Bloomberg reported the news, Chevron acknowledged it was in exclusive talks with Engine No. 1 and Microsoft, but the oil and gas company offered no details.

Chevron says the proposed plant “reflects an emerging shift in how power for AI is being developed, bringing energy supply closer to demand through co-located, behind-the-meter generation to deliver reliability while helping avoid added strain on regional electricity systems. It pairs sustained, always-on demand from advanced computing with proven capability to design, build, and operate large-scale energy infrastructure.”

Development of gas-powered electrical plants for AI data centers represents a new—and potentially lucrative— business line for Chevron. In 2025, Chevron, Engine No. 1 and GE Vernova announced a partnership to produce natural gas for AI data centers in the U.S.

Chevron’s collaboration with Engine No. 1 has already secured an order for seven large natural gas turbines from GE Vernova, according to Bloomberg.

“Energy is the key to America’s AI dominance,” Chris James, founder and chief investment officer of Engine No. 1, said last year. “By using abundant domestic natural gas to generate electricity directly connected to data centers, we can secure AI leadership, drive productivity gains across our economy, and restore America’s standing as an industrial superpower.”

8 CERAWeek 2026 takeaways from a new Houston energy leader

guest column

My first CERAWeek was a blur.

Having top energy executives, policymakers, and technologists all gathered in Houston—over 11,000 of them this year—was both overwhelming and energizing. The theme was “Convergence and Competition: Energy, Technology, and Geopolitics,” and walking through the George R. Brown Convention Center, it was immediately clear that this was no ordinary industry conference.

As a first-timer with a Greentown Labs lens, here’s what really stuck with me.

Disruption is the new normal

CERAWeek 2026 was set against the backdrop of conflict in the Middle East, the continued race to power AI, and a clear throughline: disruption is increasingly the new normal. You could feel it in every hallway conversation. The ongoing conflict in the Middle East, specifically Iran’s attacks on Qatar’s Ras Laffan facility and the closure of the Strait of Hormuz, affected roughly 20% of the world’s liquified natural gas supply, and that was woven into nearly every conversation throughout the week.

Secretary of Energy Chris Wright opened the conference with “Energy is life,” then quickly turned to natural gas. “America’s superpower is natural gas,” he said, pointing to its role in industry, heat, electricity, fertilizer, exports, and leading AI and manufacturing. That set the tone early and it never really shifted.

AI is still everywhere, but the conversation has shifted

No surprise that AI dominated the agenda. But what struck me as a first-timer was how much the conversation had matured. The AI discussion has moved from general enthusiasm to a much more practical focus on real use cases and measurable outcomes.

NVIDIA, Anthropic, and CyrusOne joined the established tech presences of Microsoft, Google, and AWS, occupying the Innovation Agora’s new AI Hub, which displaced the hydrogen hub from prior years. That detail alone tells you something about where the energy conversation has shifted. Annual global investment in data centers reached $771 billion in 2025, nearly on par with oil and gas ($835 billion) and renewable energy ($798 billion). We are not talking about a niche technology story anymore. This is a capital story, an infrastructure story, and an energy story all at once.

The prevailing tone was uncertain; the gap between what is being announced and what can actually be delivered was the subtext of almost every conversation. Transmission takes over a decade to build. The new generation takes five to nine years. AI infrastructure moves on three-to-five-year timelines. The math doesn’t work yet, and everyone is aware.

Pitch competitions still draw crowds

The Energy Venture Day and Pitch Competition at the McKinney Balcony was one of my favorite events of the week. Seeing Greentown members on that stage never gets old, but what really energized me was the broader mix: students, new founders, and veteran entrepreneurs in one space, all talking about how what they’re building is going to impact the world. S&P Global launched the NextGen cohort with 100+ graduate students from around the country getting a front-row seat to the energy sector.

Geothermal may have stolen the show

If I had to pick the most surprising theme of my first CERAWeek, it was geothermal. It drew the most consistent endorsement of the week, with Department of Energy representatives, oil and gas majors, and operators broadly aligned on its potential. Project InnerSpace hosted a dedicated Geothermal House for the first time, launching a standardized resource classification framework with the Society of Petroleum Engineers and an XPRIZE collaboration targeting surface-plant supply chain breakthroughs. For a sector that has lived in the shadows of wind and solar for years, CERAWeek 2026 was geothermal’s time to shine.

Wow, was I impressed with Melanie Nakagawa

Melanie Nakagawa, chief sustainability officer at Microsoft, delivered an impressive keynote during her fireside chat with Brad Burke. Her depth of experience, from the U.S. Department of State and venture capital to her current role at Microsoft, was matched only by her calm, hopeful demeanor. Leaders like her at the helm of climate action inspire genuine confidence in the future.

What about hydrogen?

Hydrogen was notably absent from the main stage. The AI Hub in the Innovation Agora displaced the hydrogen hub that had been a fixture in prior years. Seems like hydrogen still plays a role, but not as quickly or broadly as hoped. Blue hydrogen is moving forward cautiously. It wasn’t gone from the conversation entirely, but it no longer commands the room.

The label problem isn’t going away

Politics continues to polarize the industry. Climatetech, sustainability, cleantech — some labels carry broad objectives, others have become tribal signals. “Energy transition” for some means a replacement of fossil fuels; for others, it means an evolution across multiple dimensions simultaneously. CERAWeek 2026 showed an industry increasingly focused not on feel-good narratives about the future of energy, but on the harder questions of security, buildout, reliability, affordability, and competitiveness. A pragmatic shift may be the best answer to the label problem.

Collaboration isn’t optional—it’s strategic

The energy transition is no longer primarily an environmental story. It has become a technology and national competitiveness story. The problems are too big for any one company, sector, or country to solve alone. From incubators and investors to utilities and hyperscalers, the message was consistent all week: move together or we don’t move. S&P Global introduced “The Bridge,” a new venue specifically for energy-tech crossover conversations: a small but meaningful signal that even the conference organizers recognize that collaboration will get us further.

The scale and the energy in the room (pun intended) are what stood out most from my first CERAWeek. The industry knows what needs to get built. The question now is whether we can work together to build it fast enough.

See you next year, CERAWeek.

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Kelsey Kearns is director of Greentown Houston with more than a decade of experience in the technology sector. She served as director of community strategy for Greentown Houston from September 2025 to February 2026. Before that, she was director of business development for Howdy.com.

Houston nuclear startup launches at CERAWeek, plans Texas facility

going nuclear

A new nuclear energy startup launched last month during CERAWeek in the Bayou City.

FluxPoint Energy, the new Houston- and McLean, Virginia-based company, plans to develop the nation’s first new uranium conversion facility in more than 70 years, an effort CEO and founder Mike Chilton says is critical to unlocking the next phase of nuclear energy growth.

"Policymakers, utilities, and developers increasingly point to fuel availability as a limiting factor for America's nuclear reactors—both present and future," Chilton said in a news release. "Uranium conversion has become an unacceptable chokepoint in a global supply chain still dominated by foreign providers."

Chilton has held leadership roles at Pegasus-Global Holdings and GE Verona Hitachi Global Nuclear Fuels. Rodrigo Gonzalez Arbizu serves as COO and Christopher J. Rimel as chief of staff. The Board of Advisors includes energy leaders, including Jeff Lyash, John Sharp, Jane Stricker, Jennifer Skylakos, Leo Weitzenhoff and Jay Wileman.

FluxPoint’s planned facility will convert uranium oxide into uranium hexafluoride (UF6). Although FluxPoit’s new facility is still far off, the company announced it had secured a site and completed both market and feasibility studies. The specific area has not been revealed, only that it will be in Texas.

Discussions at CERAWeek revolved around securing reliable sources of uranium.

Nuclear energy production has been stagnant or even in slight decline since the 1990s. Concerns about nuclear waste and safety, as well as prohibitive costs, have kept new plants from being built, while the widespread availability of cheap natural gas has made investing in nuclear power less profitable. Many see the technology as dangerous and outdated.

However, as energy crises become more common, companies like FluxPoint are looking to restart the nuclear energy sector. The industry got a boost under the Biden Administration thanks to the Inflation Reduction Act, which set goals of adding 35 gigawatts of new capacity by 2035.

Chilton participated in a panel on the best ways to ensure American nuclear plants have access to uranium, most of which is not mined in the United States.

"America cannot lead in nuclear energy while relying on foreign-controlled fuel processing," Chilton added. "FluxPoint was created to restore a critical piece of our nation's energy infrastructure—ensuring that U.S. reactors have access to a secure, domestic fuel supply. This is about energy security, economic strength, and global leadership."