Solugen claims a spot on CNBC’s annual Disruptor 50 list, which highlights private companies that are “upending the classic definition of disruption.” Photo via solugen.com

Houston-based biotech startup Solugen is making waves among innovative companies.

Solugen appears at No. 36 on CNBC’s annual Disruptor 50 list, which highlights private companies that are “upending the classic definition of disruption.” Privately owned startups founded after January 1, 2009, were eligible for the Disruptor 50 list.

Founded in 2016, Solugen replaces petroleum-based products with plant-derived substitutes through its Bioforge manufacturing platform. For example, it uses engineered enzymes and metal catalysts to convert feedstocks like sugar into chemicals that have traditionally been made from fossil fuels, such as petroleum and natural gas.

Solugen has raised $643 million in funding and now boasts a valuation of $2.2 billion.

“Sparked by a chance medical school poker game conversation in 2016, Solugen evolved from prototype to physical asset in five years, and production hit commercial scale shortly thereafter,” says CNBC.

Solugen co-founders Gaurab Chakrabarti and Sean Hunt received the Entrepreneur of The Year 2023 National Award, presented by professional services giant EY.

“Solugen is a textbook startup launched by two partners with $10,000 in seed money that is revolutionizing the chemical refining industry. The innovation-driven company is tackling impactful, life-changing issues important to the planet,” Entrepreneur of The Year judges wrote.

In April 2024, Solugen broke ground on a Bioforge biomanufacturing plant in Marshall, Minnesota. The 500,000-square-foot, 34-acre facility arose through a Solugen partnership with ADM. Chicago-based ADM produces agricultural products, commodities, and ingredients. The plant is expected to open in the fall of 2025.

“Solugen’s … technology is a transformative force in sustainable chemical manufacturing,” says Hunt. “The new facility will significantly increase our existing capabilities, enabling us to expand the market share of low-carbon chemistries.”

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This article originally ran on InnovationMap.

Gaurab Chakrabarti and Sean Hunt were originally named regional winners in this year's competition this summer along with nine other Houston entrepreneurs. Photos via solugen.com

Houston sustainability startup founders named winners for 2023 Entrepreneur of the Year awards

winner, winner

Houston’s Gaurab Chakrabarti and Sean Hunt, the founders of the transformative chemical manufacturing company Solugen, have been named EY’s US National Award winners for Entrepreneur of the Year.

Solugen, also recently named a finalist in the 2023 Houston Innovation Awards, is an environmentally friendly approach that relies on smaller chemical refineries that helps in reducing costs and transportation-related emissions.

Some of their noted accomplishments includes innovations like the proprietary reactor, dubbed the Bioforge, which is a carbon-negative molecule factory and manufacturing process produces zero wastewater or emissions compared with traditional petrochemical refineries.The Bioforge uses a chemienzymatic process in converting plant-sourced substances into essential materials that can be used instead of fossil fuels.

Chakrabarti and Hunt were originally named regional winners in this year's competition this summer along with nine other Houston entrepreneurs.

Founded in 2016 by Hunt and Gaurab Chakrabarti, Solugen has raised over $600 million from investors like Sasol that believe in the technology's potential. The company is valued at reportedly over $2 billion. Solugen is headquartered in Houston, not because it is the hometown of Chakrabarti, but for what Houston brings to the company.

“There’s no way our business could succeed in the Bay Area," Chakrabarti said in a 2023 interview at SXSW where he detailed the offers Hunt and he received to move the business out of state. “For our business, if you look at the density of chemical engineers, the density of our potential customers, and the density of people who know how to do enzyme engineering, Houston happened to be that perfect trifecta for us.”

Even though they are headquartered in Houston, Solugen recently secured plans to expand to the Midwest, as in November they announced its newest strategic partnership with sustainable solutions company ADM (NYSE:ADM) in Marshall, Minnesota. The partnership includes plans for Solugen to build a 500,000-square-foot biomanufacturing facility next to an existing ADM facility , with the two companies working together on producing biomaterials to replace fossil fuel products.

“The strategic partnership with ADM will allow Solugen to bring our chemienzymatic process to a commercial scale and meet existing customer demand for our high-performance, cost-competitive, sustainable products,” Chakrabarti said in a news release. “As one of the few scaled-up and de-risked biomanufacturing assets in the country, Solugen’s Bioforge platform is helping bolster domestic capabilities and supply chains that are critical in ensuring the U.S. reaches its ambitious climate targets.”

For Chakrabarti and Hunt, Solugen was born out of a 12-year friendship, and the journey began after a friendly card game. After an entrepreneurship contest at MIT, which earned them second place and a $10,000 prize, they invested the winnings to work on what would become Solugen, a proof-of-concept reactor with materials bought from a local home improvement store.

"We had a conviction that we were building something that could be impactful to the rest of the world,” Chakrabarti said at SXSW in 2023.

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This article originally ran on InnovationMap.

Houston-based Solugen will build a 500,000-square-foot biomanufacturing facility in the Midwest thanks to a new strategic partnership.

Houston-based sustainable chemicals co. to build ​Midwest biomanufacturing facility

it's corn

Solugen has scored a partnership with a global company to build a biomanufacturing facility adjacent to an existing corn complex in Marshall, Minnesota.

Solugen, a Houston company that's designed a process that converts plant-derived substances into essential materials, has announced its newest strategic partnership with sustainable solutions company ADM (NYSE:ADM). The partnership includes plans for Solugen to build a 500,000-square-foot biomanufacturing facility next to an existing ADM facility in the Midwest. The two companies will collaborate on producing biomaterials to replace fossil fuel-based products.

“The strategic partnership with ADM will allow Solugen to bring our chemienzymatic process to a commercial scale and meet existing customer demand for our high-performance, cost-competitive, sustainable products,” Gaurab Chakrabarti, co-founder and CEO of Solugen, says in a news release. “As one of the few scaled-up and de-risked biomanufacturing assets in the country, Solugen’s Bioforge platform is helping bolster domestic capabilities and supply chains that are critical in ensuring the U.S. reaches its ambitious climate targets.”

The company plans to begin on-site construction early next year, with plans to startup in the first half of 2025. The project should create at least 40 permanent jobs and 100 temporary construction positions.

“Sustainability is one of the enduring global trends powering ADM’s growth and underpinning the strategic evolution of our Carbohydrate Solutions business,” Chris Cuddy, president of ADM’s Carbohydrate Solutions business, says in the release. “ADM is one of the largest dextrose producers in the world, and this strategic partnership will allow us to further diversify our product stream as we continue to support plant-based solutions spanning sustainable packaging, pharma, plant health, construction, fermentation, and home and personal care.”

Founded in 2016 by Chakrabarti and Sean Hunt, Solugen's carbon-negative molecule factory, named the Bioforge, uses its chemienzymatic process in converting plant-sourced substances into essential materials that can be used instead of fossil fuels. The manufacturing process is carbon neutral, and Solugen has raised over $600 million from investors that believe in the technology's potential.

“The initial phase of the project will significantly increase Solugen’s manufacturing capacity, which is critical for commercializing our existing line of molecules and kicks off plans for a multi-phase large-scale U.S. Bioforge buildout,” Hunt, CTO of Solugen, says in the release. “The increase in capacity will also free up our Houston operation for research and development efforts into additional molecules and market applications.”

The project should create at least 40 permanent jobs and 100 temporary construction positions.

"As a community with a strong foundation of agriculture and innovation, we look forward to welcoming Solugen to Marshall. This industry-leading facility will serve as a powerful economic driver for the city, creating new jobs and diversifying our industry,” City of Marshall Mayor Bob Byrnes says in the statement. "We are thankful for ADM’s longstanding commitment and impact to Marshall, which has paved the way for this remarkable partnership and continues to further economic growth to our region."

It's the second major company partnership announcement Solugen has made this month, with a new arrangement with Sasol being secured last week.

Solugen and Sasol have entered into a strategic partnership. Photo via Solugen

Houston-based sustainable chemicals company secures major partnership with Sasol

cleaner chemicals

A Houston company that's creating cleaner chemicals with little to no impact on the environment has scored a partnership with a major chemicals producer.

Solugen and Sasol Chemicals, a business unit of Saslo Ltd., revealed that they are working together to explore commercialization of sustainably-made home and personal care products.

“This agreement is an example of our approach of partnering to find innovative solutions for our customers,” Jonathan Ward, senior manager of Strategy and Sustainable Growth for Sasol’s Essential Care Chemicals business division, says in a news release. “Our focus is delivering high-performing products with lower carbon footprints at competitive prices, and we are eager to see how Solugen’s products might help us do that.”

Founded in 2016 by Sean Hunt and Gaurab Chakrabarti, Solugen's carbon-negative molecule factory, named the Bioforge, uses a chemienzymatic process in converting plant-sourced substances into essential materials that can be used instead of fossil fuels. The manufacturing process is carbon neutral, and Solugen has raised over $600 million from investors that believe in the technology's potential.

"We are thrilled to partner with Sasol Chemicals, one of the world’s largest producers of surfactants, to drive positive impact in the home and personal care market,” Chakrabarti, CEO of Solugen, says in the release. “Sasol’s commitment to sustainability makes it an ideal partner for Solugen. We look forward to leveraging our combined strengths in technology, production, and market development to meet increasing consumer demand for our high-performance, bio-based solutions.”

Chakrabarti shared some of the secrets to Solugen's success and early partnerships at a SXSW panel earlier this year. The company was also recently named a finalist in the 2023 Houston Innovation Awards.

These Houston-area executives were recognized by EY's annual regional awards. Photos courtesy

Houston energy leaders score wins at annual regional entrepreneur competition

eyes on EY

You might say that four Houston executives with ties to the energy sector are energized about an award they just received.

The four executives recently were named winners in the Gulf South division of the Entrepreneur Of The Year awards program. They’ll now compete at the national level.

The one winner who works directly in the energy industry is Roger Jenkins, president and CEO of Houston-based Murphy Oil. Jenkins rose to the company’s top positions in 2013. He joined Murphy Oil in 2001 as a drilling manager in Malaysia.

Jenkins earned a bachelor’s degree in petroleum engineering from Louisiana State University and an MBA from Harvard University’s business school.

Murphy Oil is an oil and natural gas exploration and production company that operates primarily onshore in the U.S. and Canada, and offshore in the Gulf of Mexico.

A Fortune 1000 company founded in 1944, Murphy Oil generated revenue of nearly $4 billion in 2022.

In 2020, the company announced it was shuttering its headquarters in El Dorado, Arkansas, as well as its location in Calgary, Canada, and consolidating its operations into a new main office in Houston. About 190 Murphy Oil employees worked in El Dorado and Calgary.

“Our ongoing execution excellence across our significant offshore backlog and over 1,000 oil-weighted onshore locations will ensure that we will remain a long-term sustainable company,” Jenkins told Wall Street analysts in May 2023.

While not exactly an energy company, Solugen's co-founders — Gaurab Chakrabarti, CEO, and Sean Hunt, CTO — are representing the clean chemicals space within the energy transition.

Solugen, founded in 2016, makes and distributes specialty chemicals derived from feedstock. The startup is reportedly valued at more than $2 billion. To date, Solugen has raised $642.2 million, according to Crunchbase.

In naming Solugen one of the most innovative companies of 2022, Fast Company noted that the carbon-negative process embraced by Solugen and the startup’s “ability to sell flexible amounts of chemicals to companies looking to lower their own footprint have helped the company make inroads in a traditionally slow-moving industry.”

Another Houston executive with connections to the energy sector also is regional Entrepreneur Of The Year winners.

Ludmila Golovine is president and CEO of Houston-based MasterWord Services. The company provides translation and interpretation services in more than 400 languages for clients in sectors like energy, health care, and tech. The woman-owned business launched in 1993.

“It is a great honor for me and for MasterWord to be recognized alongside the other EY Entrepreneur Of The Year winners,” Golovine says in a news release about the Entrepreneur Of The Year honor.

In all, 10 executives from Houston-based companies were hailed as 2023 regional winners in the Entrepreneur Of The Year program, run by professional services firm EY. Aside from Jenkins, Golovine, Walker, and Smith, they are:

  • Steve Altemus, president and CEO of space exploration company Intuitive Machines.
  • Mark Walker, co-founder, chairman and CEO of Houston-based Direct Digital Holdings, and Keith Smith, co-founder and president. Direct Digital Holdings operates advertising platforms for clients in sectors such as energy, health care, travel and financial services.
  • Daryl Dudum and Matthew Hadda, founders and co-CEOs of Specialty1 Partners. The company provides business services to dental surgery practices.
  • Mohammad Millwala, founder and CEO of DM Clinical Research. The company operates 13 sites for clinical trials.

Also grabbing a regional award is Omair Tariq, co-founder and CEO of Austin-based Cart.com. The company, which provides software and services to online merchants, relocated its headquarters from Houston to Austin in 2021. Tariq remains in Houston, though.

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Houston microgrid company names new CEO

new hire

Houston-based electric microgrid company Enchanted Rock has named a new CEO.

John Carrington has assumed the role after serving as Enchanted Rock's executive chairman since June, the company announced earlier this month.

Carrington most recently was CEO of Houston-based Stem, which offers AI-enabled software and services designed for setting up and operating clean energy facilities. He stepped down as Stem’s CEO in September 2024. Stem, which was founded in 2006 and went public under Carrington's leadership in 2021, was previously based in San Francisco.

Carrington has also held senior leadership roles at Miasolé, First Solar and GE.

Corey Amthor has served as acting CEO of Enchanted Rock since June. He succeeded Enchanted Rock founder Thomas McAndrew in the role, with McAndrew staying on with the company as a strategic advisor and board member. With the hiring of Carrington, Amthor has returned to his role as president. According to the company, Amthor and Carrington will "partner to drive the company’s next phase of growth."

“I’m proud to join a leadership team known for technical excellence and execution, and with our company-wide commitment to innovation, we are well positioned to navigate this moment of unprecedented demand and advance our mission alongside our customers nationwide,” Carrington said in the news release. “Enchanted Rock’s technology platform delivers resilient, clean and scalable ultra-low-emissions onsite power that solves some of the most urgent challenges facing our country today. I’m energized by the strong momentum and growing market demand for our solutions, and we remain committed to providing data centers and other critical sectors with the reliable power essential to their operations.”

This summer, Enchanted Rock also announced that Ian Blakely would reassume the role of CFO at the company. He previously served as chief strategy officer. Paul Froutan, Enchanted Rock's former CTO, was also named COO last year.

6 major acquisitions that fueled the Houston energy sector in 2025

2025 In Review

Editor's note: As 2025 comes to a close, we're revisiting the biggest headlines and major milestones of the energy transition sector this year. Here are six major acquisitions that fueled the Houston energy industry in 2025:

Houston-based Calpine Corp. to be acquired in clean energy megadeal

Houston's Calpine Corp. will be acquired by Baltimore-based nuclear power company Constellation Energy Corp. Photo via DOE

In January 2025, Baltimore-based nuclear power company Constellation Energy Corp. and Houston-based Calpine Corp. entered into an agreement where Constellation would acquire Calpine in a cash and stock transaction with an overall net purchase price of $26.6 billion. The deal received final regulatory clearance this month.

Investment giant to acquire TXNM Energy for $11.5 billion

Blackstone Infrastructure, an affiliate of Blackstone Inc., will acquire a major Texas electricity provider. Photo via Shutterstock

In May 2025, Blackstone Infrastructure, an investment giant with $600 million in assets under management, agreed to buy publicly traded TXNM Energy in a debt-and-stock deal valued at $11.5 billion. The deal recently cleared a major regulatory hurdle, but still must be approved by the Public Utility Commission of Texas.

Houston's Rhythm Energy expands nationally with clean power acquisition

PJ Popovic, founder and CEO of Houston-based Rhythm Energy, which has acquired Inspire Clean Energy. Photo courtesy of Rhythm

Houston-based Rhythm Energy Inc. acquired Inspire Clean Energy in June 2025 for an undisclosed amount. The deal allowed Rhythm to immediately scale outside of Texas and into the Northeast, Midwest and mid-Atlantic regions.

Houston American Energy closes acquisition of New York low-carbon fuel co.

Houston American Energy Corp. has acquired Abundia Global Impact Group, which converts plastic and certified biomass waste into high-quality renewable fuels. Photo via Getty Images.

Renewable energy company Houston American Energy Corp. (NYSE: HUSA) acquired Abundia Global Impact Group in July 2025. The acquisition created a combined company focused on converting waste plastics into high-value, drop-in, low-carbon fuels and chemical products.

Chevron gets green light on $53 billion Hess acquisition

With the deal, Chevron gets access to one of the biggest oil finds of the decade. Photo via Chevron

In July 2025, Houston-based Chevron scored a critical ruling in Paris that provided the go-ahead for a $53 billion acquisition of Hess and access to one of the biggest oil finds of the decade. Chevron completed its acquisition of Hess shortly after the ruling from the International Chamber of Commerce in Paris.

Investors close partial acquisition of Phillips 66 subsidiary with growing EV network

Two investment firms have scooped up the majority stake in JET, a subsidiary of Phillips 66 with a rapidly growing EV charging network. Photo via Jet.de Facebook.

In December 2025, Energy Equation Partners, a London-based investment firm focused on clean energy companies, and New York-based Stonepeak completed the acquisition of a 65 percent interest in JET Tankstellen Deutschland GmbH, a subsidiary of Houston oil and gas giant Phillips 66.

Houston researchers develop energy-efficient film for AI chips

AI research

A team of researchers at the University of Houston has developed an innovative thin-film material that they believe will make AI devices faster and more energy efficient.

AI data centers consume massive amounts of electricity and use large cooling systems to operate, adding a strain on overall energy consumption.

“AI has made our energy needs explode,” Alamgir Karim, Dow Chair and Welch Foundation Professor at the William A. Brookshire Department of Chemical and Biomolecular Engineering at UH, explained in a news release. “Many AI data centers employ vast cooling systems that consume large amounts of electricity to keep the thousands of servers with integrated circuit chips running optimally at low temperatures to maintain high data processing speed, have shorter response time and extend chip lifetime.”

In a report recently published in ACS Nano, Karim and a team of researchers introduced a specialized two-dimensional thin film dielectric, or electric insulator. The film, which does not store electricity, could be used to replace traditional, heat-generating components in integrated circuit chips, which are essential hardware powering AI.

The thinner film material aims to reduce the significant energy cost and heat produced by the high-performance computing necessary for AI.

Karim and his former doctoral student, Maninderjeet Singh, used Nobel prize-winning organic framework materials to develop the film. Singh, now a postdoctoral researcher at Columbia University, developed the materials during his doctoral training at UH, along with Devin Shaffer, a UH professor of civil engineering, and doctoral student Erin Schroeder.

Their study shows that dielectrics with high permittivity (high-k) store more electrical energy and dissipate more energy as heat than those with low-k materials. Karim focused on low-k materials made from light elements, like carbon, that would allow chips to run cooler and faster.

The team then created new materials with carbon and other light elements, forming covalently bonded sheetlike films with highly porous crystalline structures using a process known as synthetic interfacial polymerization. Then they studied their electronic properties and applications in devices.

According to the report, the film was suitable for high-voltage, high-power devices while maintaining thermal stability at elevated operating temperatures.

“These next-generation materials are expected to boost the performance of AI and conventional electronics devices significantly,” Singh added in the release.

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This article originally appeared on our sister site, InnovationMap.