Solugen claims a spot on CNBC’s annual Disruptor 50 list, which highlights private companies that are “upending the classic definition of disruption.” Photo via solugen.com

Houston-based biotech startup Solugen is making waves among innovative companies.

Solugen appears at No. 36 on CNBC’s annual Disruptor 50 list, which highlights private companies that are “upending the classic definition of disruption.” Privately owned startups founded after January 1, 2009, were eligible for the Disruptor 50 list.

Founded in 2016, Solugen replaces petroleum-based products with plant-derived substitutes through its Bioforge manufacturing platform. For example, it uses engineered enzymes and metal catalysts to convert feedstocks like sugar into chemicals that have traditionally been made from fossil fuels, such as petroleum and natural gas.

Solugen has raised $643 million in funding and now boasts a valuation of $2.2 billion.

“Sparked by a chance medical school poker game conversation in 2016, Solugen evolved from prototype to physical asset in five years, and production hit commercial scale shortly thereafter,” says CNBC.

Solugen co-founders Gaurab Chakrabarti and Sean Hunt received the Entrepreneur of The Year 2023 National Award, presented by professional services giant EY.

“Solugen is a textbook startup launched by two partners with $10,000 in seed money that is revolutionizing the chemical refining industry. The innovation-driven company is tackling impactful, life-changing issues important to the planet,” Entrepreneur of The Year judges wrote.

In April 2024, Solugen broke ground on a Bioforge biomanufacturing plant in Marshall, Minnesota. The 500,000-square-foot, 34-acre facility arose through a Solugen partnership with ADM. Chicago-based ADM produces agricultural products, commodities, and ingredients. The plant is expected to open in the fall of 2025.

“Solugen’s … technology is a transformative force in sustainable chemical manufacturing,” says Hunt. “The new facility will significantly increase our existing capabilities, enabling us to expand the market share of low-carbon chemistries.”

———

This article originally ran on InnovationMap.

Gaurab Chakrabarti and Sean Hunt were originally named regional winners in this year's competition this summer along with nine other Houston entrepreneurs. Photos via solugen.com

Houston sustainability startup founders named winners for 2023 Entrepreneur of the Year awards

winner, winner

Houston’s Gaurab Chakrabarti and Sean Hunt, the founders of the transformative chemical manufacturing company Solugen, have been named EY’s US National Award winners for Entrepreneur of the Year.

Solugen, also recently named a finalist in the 2023 Houston Innovation Awards, is an environmentally friendly approach that relies on smaller chemical refineries that helps in reducing costs and transportation-related emissions.

Some of their noted accomplishments includes innovations like the proprietary reactor, dubbed the Bioforge, which is a carbon-negative molecule factory and manufacturing process produces zero wastewater or emissions compared with traditional petrochemical refineries.The Bioforge uses a chemienzymatic process in converting plant-sourced substances into essential materials that can be used instead of fossil fuels.

Chakrabarti and Hunt were originally named regional winners in this year's competition this summer along with nine other Houston entrepreneurs.

Founded in 2016 by Hunt and Gaurab Chakrabarti, Solugen has raised over $600 million from investors like Sasol that believe in the technology's potential. The company is valued at reportedly over $2 billion. Solugen is headquartered in Houston, not because it is the hometown of Chakrabarti, but for what Houston brings to the company.

“There’s no way our business could succeed in the Bay Area," Chakrabarti said in a 2023 interview at SXSW where he detailed the offers Hunt and he received to move the business out of state. “For our business, if you look at the density of chemical engineers, the density of our potential customers, and the density of people who know how to do enzyme engineering, Houston happened to be that perfect trifecta for us.”

Even though they are headquartered in Houston, Solugen recently secured plans to expand to the Midwest, as in November they announced its newest strategic partnership with sustainable solutions company ADM (NYSE:ADM) in Marshall, Minnesota. The partnership includes plans for Solugen to build a 500,000-square-foot biomanufacturing facility next to an existing ADM facility , with the two companies working together on producing biomaterials to replace fossil fuel products.

“The strategic partnership with ADM will allow Solugen to bring our chemienzymatic process to a commercial scale and meet existing customer demand for our high-performance, cost-competitive, sustainable products,” Chakrabarti said in a news release. “As one of the few scaled-up and de-risked biomanufacturing assets in the country, Solugen’s Bioforge platform is helping bolster domestic capabilities and supply chains that are critical in ensuring the U.S. reaches its ambitious climate targets.”

For Chakrabarti and Hunt, Solugen was born out of a 12-year friendship, and the journey began after a friendly card game. After an entrepreneurship contest at MIT, which earned them second place and a $10,000 prize, they invested the winnings to work on what would become Solugen, a proof-of-concept reactor with materials bought from a local home improvement store.

"We had a conviction that we were building something that could be impactful to the rest of the world,” Chakrabarti said at SXSW in 2023.

———

This article originally ran on InnovationMap.

Houston-based Solugen will build a 500,000-square-foot biomanufacturing facility in the Midwest thanks to a new strategic partnership.

Houston-based sustainable chemicals co. to build ​Midwest biomanufacturing facility

it's corn

Solugen has scored a partnership with a global company to build a biomanufacturing facility adjacent to an existing corn complex in Marshall, Minnesota.

Solugen, a Houston company that's designed a process that converts plant-derived substances into essential materials, has announced its newest strategic partnership with sustainable solutions company ADM (NYSE:ADM). The partnership includes plans for Solugen to build a 500,000-square-foot biomanufacturing facility next to an existing ADM facility in the Midwest. The two companies will collaborate on producing biomaterials to replace fossil fuel-based products.

“The strategic partnership with ADM will allow Solugen to bring our chemienzymatic process to a commercial scale and meet existing customer demand for our high-performance, cost-competitive, sustainable products,” Gaurab Chakrabarti, co-founder and CEO of Solugen, says in a news release. “As one of the few scaled-up and de-risked biomanufacturing assets in the country, Solugen’s Bioforge platform is helping bolster domestic capabilities and supply chains that are critical in ensuring the U.S. reaches its ambitious climate targets.”

The company plans to begin on-site construction early next year, with plans to startup in the first half of 2025. The project should create at least 40 permanent jobs and 100 temporary construction positions.

“Sustainability is one of the enduring global trends powering ADM’s growth and underpinning the strategic evolution of our Carbohydrate Solutions business,” Chris Cuddy, president of ADM’s Carbohydrate Solutions business, says in the release. “ADM is one of the largest dextrose producers in the world, and this strategic partnership will allow us to further diversify our product stream as we continue to support plant-based solutions spanning sustainable packaging, pharma, plant health, construction, fermentation, and home and personal care.”

Founded in 2016 by Chakrabarti and Sean Hunt, Solugen's carbon-negative molecule factory, named the Bioforge, uses its chemienzymatic process in converting plant-sourced substances into essential materials that can be used instead of fossil fuels. The manufacturing process is carbon neutral, and Solugen has raised over $600 million from investors that believe in the technology's potential.

“The initial phase of the project will significantly increase Solugen’s manufacturing capacity, which is critical for commercializing our existing line of molecules and kicks off plans for a multi-phase large-scale U.S. Bioforge buildout,” Hunt, CTO of Solugen, says in the release. “The increase in capacity will also free up our Houston operation for research and development efforts into additional molecules and market applications.”

The project should create at least 40 permanent jobs and 100 temporary construction positions.

"As a community with a strong foundation of agriculture and innovation, we look forward to welcoming Solugen to Marshall. This industry-leading facility will serve as a powerful economic driver for the city, creating new jobs and diversifying our industry,” City of Marshall Mayor Bob Byrnes says in the statement. "We are thankful for ADM’s longstanding commitment and impact to Marshall, which has paved the way for this remarkable partnership and continues to further economic growth to our region."

It's the second major company partnership announcement Solugen has made this month, with a new arrangement with Sasol being secured last week.

Solugen and Sasol have entered into a strategic partnership. Photo via Solugen

Houston-based sustainable chemicals company secures major partnership with Sasol

cleaner chemicals

A Houston company that's creating cleaner chemicals with little to no impact on the environment has scored a partnership with a major chemicals producer.

Solugen and Sasol Chemicals, a business unit of Saslo Ltd., revealed that they are working together to explore commercialization of sustainably-made home and personal care products.

“This agreement is an example of our approach of partnering to find innovative solutions for our customers,” Jonathan Ward, senior manager of Strategy and Sustainable Growth for Sasol’s Essential Care Chemicals business division, says in a news release. “Our focus is delivering high-performing products with lower carbon footprints at competitive prices, and we are eager to see how Solugen’s products might help us do that.”

Founded in 2016 by Sean Hunt and Gaurab Chakrabarti, Solugen's carbon-negative molecule factory, named the Bioforge, uses a chemienzymatic process in converting plant-sourced substances into essential materials that can be used instead of fossil fuels. The manufacturing process is carbon neutral, and Solugen has raised over $600 million from investors that believe in the technology's potential.

"We are thrilled to partner with Sasol Chemicals, one of the world’s largest producers of surfactants, to drive positive impact in the home and personal care market,” Chakrabarti, CEO of Solugen, says in the release. “Sasol’s commitment to sustainability makes it an ideal partner for Solugen. We look forward to leveraging our combined strengths in technology, production, and market development to meet increasing consumer demand for our high-performance, bio-based solutions.”

Chakrabarti shared some of the secrets to Solugen's success and early partnerships at a SXSW panel earlier this year. The company was also recently named a finalist in the 2023 Houston Innovation Awards.

These Houston-area executives were recognized by EY's annual regional awards. Photos courtesy

Houston energy leaders score wins at annual regional entrepreneur competition

eyes on EY

You might say that four Houston executives with ties to the energy sector are energized about an award they just received.

The four executives recently were named winners in the Gulf South division of the Entrepreneur Of The Year awards program. They’ll now compete at the national level.

The one winner who works directly in the energy industry is Roger Jenkins, president and CEO of Houston-based Murphy Oil. Jenkins rose to the company’s top positions in 2013. He joined Murphy Oil in 2001 as a drilling manager in Malaysia.

Jenkins earned a bachelor’s degree in petroleum engineering from Louisiana State University and an MBA from Harvard University’s business school.

Murphy Oil is an oil and natural gas exploration and production company that operates primarily onshore in the U.S. and Canada, and offshore in the Gulf of Mexico.

A Fortune 1000 company founded in 1944, Murphy Oil generated revenue of nearly $4 billion in 2022.

In 2020, the company announced it was shuttering its headquarters in El Dorado, Arkansas, as well as its location in Calgary, Canada, and consolidating its operations into a new main office in Houston. About 190 Murphy Oil employees worked in El Dorado and Calgary.

“Our ongoing execution excellence across our significant offshore backlog and over 1,000 oil-weighted onshore locations will ensure that we will remain a long-term sustainable company,” Jenkins told Wall Street analysts in May 2023.

While not exactly an energy company, Solugen's co-founders — Gaurab Chakrabarti, CEO, and Sean Hunt, CTO — are representing the clean chemicals space within the energy transition.

Solugen, founded in 2016, makes and distributes specialty chemicals derived from feedstock. The startup is reportedly valued at more than $2 billion. To date, Solugen has raised $642.2 million, according to Crunchbase.

In naming Solugen one of the most innovative companies of 2022, Fast Company noted that the carbon-negative process embraced by Solugen and the startup’s “ability to sell flexible amounts of chemicals to companies looking to lower their own footprint have helped the company make inroads in a traditionally slow-moving industry.”

Another Houston executive with connections to the energy sector also is regional Entrepreneur Of The Year winners.

Ludmila Golovine is president and CEO of Houston-based MasterWord Services. The company provides translation and interpretation services in more than 400 languages for clients in sectors like energy, health care, and tech. The woman-owned business launched in 1993.

“It is a great honor for me and for MasterWord to be recognized alongside the other EY Entrepreneur Of The Year winners,” Golovine says in a news release about the Entrepreneur Of The Year honor.

In all, 10 executives from Houston-based companies were hailed as 2023 regional winners in the Entrepreneur Of The Year program, run by professional services firm EY. Aside from Jenkins, Golovine, Walker, and Smith, they are:

  • Steve Altemus, president and CEO of space exploration company Intuitive Machines.
  • Mark Walker, co-founder, chairman and CEO of Houston-based Direct Digital Holdings, and Keith Smith, co-founder and president. Direct Digital Holdings operates advertising platforms for clients in sectors such as energy, health care, travel and financial services.
  • Daryl Dudum and Matthew Hadda, founders and co-CEOs of Specialty1 Partners. The company provides business services to dental surgery practices.
  • Mohammad Millwala, founder and CEO of DM Clinical Research. The company operates 13 sites for clinical trials.

Also grabbing a regional award is Omair Tariq, co-founder and CEO of Austin-based Cart.com. The company, which provides software and services to online merchants, relocated its headquarters from Houston to Austin in 2021. Tariq remains in Houston, though.

Ad Placement 300x100
Ad Placement 300x600

CultureMap Emails are Awesome

8+ must-attend Houston energy transition events in October 2026

Must-Attend Meetings

Editor's note: October is here, and there are many energy events to plug into in Houston this month. From summits and forums to exhibitions and networking opportunities, these are the top events to put on your calendar. Learn more below, and register now.

Oct. 6-7: Hydrogen Americas Summit and Exhibition

Hydrogen Americas delivers an unparalleled opportunity to explore how hydrogen integrates with CCUS and other energy solutions under the new U.S. and Americas energy paradigm. This event moves to Houston in 2026, providing unmatched access to industry leaders and opportunities. The summit will include CCUS dedicated sessions integrated directly into the conference programming, providing deeper insights into carbon capture, utilization, and storage. Look forward to networking opportunities to connect with global suppliers, regional developers, and key policymakers.

This event begins Oct. 6 at George R. Brown Convention Center. Register here.

Oct. 6-7: Annual Energy Summit — Energy, Risk, and Geopolitics

The 10th annual energy summit is co-hosted by Baker Botts and the Center for Energy Studies at Rice University's Baker Institute. This year's summit, “Energy, Risk, and Geopolitics,” will explore how a changing geopolitical landscape and shifts in supply chain risks are impacting investment, innovation, and market dynamics. The two-day program will include discussions spanning petroleum and LNG markets, critical minerals, electricity reliability, AI, and power demand.

This event begins Oct. 6 at 7:30 am at James A Baker III Hall. The event will also be livestreamed. Register here.

Oct. 7: Industrial Data Forward Forum 2026

Houston continues to sit at the intersection of energy, chemical production, and advanced manufacturing. Industrial data experts, automation engineers, and enterprise architects will gather for this one-day forum to address one of the region's biggest operational challenges: modernizing massive, legacy industrial plants without incurring high costs.

This event takes place Oct. 7 at Norris Conference Center. Register here.

Oct. 14: Houston Engineering, Energy & Transportation Networking Event

Connect with leading engineers, energy experts, environmental innovators, and transportation professionals during an evening of collaboration, insight, and opportunity. This exclusive event is designed for engineers, project developers, renewable energy specialists, urban planners, environmental consultants, and infrastructure leaders eager to expand their networks, exchange ideas, and explore solutions driving the future of sustainable development.

This event takes place on Oct. 14 at 7 pm at SOHO Garden. Get tickets here.

Oct. 14: Future of Global Energy Conference

This October, the sixth annual Future of Global Energy Conference kicks off, convening influential leaders from across energy, technology, finance and public policy who will come together to explore the forces defining the next era of global energy and Houston’s role in shaping it. Ryan Lance, Executive Chairman of ConocoPhillips and 2027 Chair of the Greater Houston Partnership’s Board of Directors, is the keynote speaker, bringing a global perspective on rising demand, market volatility and Houston’s role in the next era of energy growth.

This event takes place Oct. 14 at Marriott Marquis. Register here.

Oct. 17: Energy Day 2026

Energy Day Houston is the nation’s largest free, family-friendly STEM festival. It features over 50 interactive exhibits and live demonstrations focused on traditional and emerging energy career paths to power up your curiosity.

This event begins at 11 am on Oct. 17 at Sam Houston Park. Get details here.

Oct. 22: Geophysical Society of Houston Fall Forum

This one-day event will explore how geophysics continues to drive value in hydrocarbon development while opening new opportunities in geothermal, critical minerals, mining, microseismic monitoring, and other emerging subsurface applications. The forum will highlight both the technologies and business strategies needed to succeed in a rapidly evolving energy landscape.

This event begins at 7 am on Oct. 22 at SLB. Get details here.

Oct. 28-29: Energy Council Houston 2026

Energy Council Houston is a private executive forum for leaders across the U.S. upstream oil and gas sector. Over two days, operators, investors, financiers, and strategic partners will come together to discuss the issues shaping capital allocation, energy security, M&A activity, and energy investment across North America.

This event begins Oct. 28 at the Four Seasons Hotel Houston. Register here.

Houston geothermal company picks Nevada site for commercial-scale project

coming soon

Sage Geosystems, a Houston-based developer of geothermal power systems, has chosen a site in Nevada for its commercial-scale Project Vector facility.

The company’s two-well enhanced geothermal system (EGS) will deliver around-the-clock geothermal heat to Ormat Technologies’ Blue Mountain geothermal power plant in Winnemucca, Nevada.

The startup expects to begin drilling the first well later this year, with the first electricity to be generated in 2027 and full-scale production to start in 2028.

In the Nevada system, fluid will circulate through an engineered subsurface reservoir, absorb heat from the surrounding rock and return heat to the surface. The heat will be delivered to the Blue Mountain plant for conversion into electricity.

Project Vector builds on the performance of Sage’s SMECI facility in South Texas. That facility’s results, combined with Sage’s digital twin platform, will be used to shape to the design and development of Project Vector.

Project Vector supports Sage’s growing commercial pipeline, including a 150-megawatt geothermal power agreement with Meta Platforms, the parent company of Facebook and Instagram.

“Blue Mountain is an ideal location for Sage to take the next step in continuing to commercialize our proprietary EGS approach,” Jason Peart, chief operating officer at Sage, said in a release. “By delivering geothermal heat into an existing power plant, Project Vector can demonstrate the model for bringing firm, 24/7 geothermal power to market at scale.”

Project Vector extends Sage’s relationship with Ormat.

In August 2025, Sage and Ormat agreed to accelerate commercialization of Sage’s geothermal technology at an Ormat power plant. This January, Ormat co-led Sage’s $97 million Series B funding round.

Sage, founded in 2020, has raised about $159 million across three funding rounds.

As the startup ramps up its ESG platform, Sage is targeting data centers as customers, among other large-scale users of electricity.

“The energy needs are huge, and they need it now,” CEO Cindy Taff said on Data Center Frontiers’ podcast. “They can’t depend on the grid anymore.”

Houston’s power advantage: Key takeaways from 2026 HETI Power Summit

The view from heti

Power has become a defining economic development issue as electricity demand rises across Texas.

Industrial expansion, advanced manufacturing, AI and data center growth are increasing the importance of reliable, affordable power delivered on the timelines major projects require.

The 2026 HETI Power Summit, titled Houston’s Power Advantage: Competing for Large-Load Growth, brought together leaders from utilities, power producers, large energy customers, technology and infrastructure providers, professional services firms and the public sector to examine how Houston can meet this moment.

Across keynotes, research report-outs, panel discussions and a fireside chat, a consistent theme emerged: Houston’s power advantage comes from the region’s ability to align utilities, customers, infrastructure, flexible demand, emerging solutions and regional partners around reliable, affordable and timely growth.

Reliability and Readiness

Public Utility Commission of Texas Commissioner Kathleen Jackson opened the summit by emphasizing reliability as the foundation for continued growth as Texas electricity demand rises.

Commissioner Jackson underscored the importance of sustained planning and investment to support new industrial, manufacturing and digital demand while maintaining a reliable power system. Remarks framed the morning’s broader discussion of how Houston can pair reliability with speed, affordability and long-term system readiness.

Scott Cockerham of FTI Consulting previewed HETI and FTI’s “Texas Power Market & Industry Assessment”. The research identifies accessibility, reliability, affordability, market flexibility and infrastructure readiness as key dimensions of regional competitiveness.

Leaders from FTI Consulting, Kroll, AWS and Constellation also discussed factors shaping major investment decisions, including reliability, infrastructure timelines, cost certainty, site readiness, community support and regional coordination.

For large customers, these factors must translate into credible project-level execution. Confidence in system performance, energization timelines and infrastructure plans can materially influence major capital commitments.

Building for the Houston We Want to Become

Jason Ryan of CenterPoint Energy challenged participants to plan now for the infrastructure needed to support Houston’s next phase of growth. Drawing on the idea that “what got you here won’t get you there,” Ryan urged the region to build infrastructure for “the Houston we want to become” and stay ahead of large-load demand.

A fireside discussion between CenterPoint Energy and Foxconn brought that challenge to the customer level. The conversation explored how early coordination between utilities and large customers can help advanced manufacturing projects move from site selection and planning to construction and operation.

Long-term growth will require continued investment in generation, transmission and distribution. In the near term, better use of existing infrastructure can create additional capacity.

HETI also shared findings from its Role of Efficiency & Demand Response to Meet Near-Term Regional Power Demand report. Energy efficiency can lower baseline electricity use, while demand response can shift or reduce demand during critical periods. Combined with supply-side investment, these tools can create grid headroom as longer-term infrastructure advances.

The summit’s closing panel, featuring leaders from Amperon, Enchanted Rock, EY and Quanta Services, expanded the discussion to emerging solutions. Panelists explored modular and flexible generation, advanced forecasting, grid intelligence and greater coordination among utilities, customers, infrastructure providers and communities.

Houston’s broader regional power landscape adds another dimension. Entergy Texas President and CEO Eli Viamontes described Southeast Texas as experiencing an “extraordinary trifecta of residential, industrial and data center growth.” His remarks highlighted how the MISO-facing portion of the region complements Houston’s ERCOT strengths through utility planning, generation and infrastructure investment, resource adequacy and coordination with major industrial customers.

Together, these approaches point to a broader strategy: invest for long-term demand while using flexibility, technology and regional coordination to create capacity for growth today.

From Power Advantage to Economic Advantage

Taken together, the Power Summit discussions point to a clear priority for Houston: translating power market and infrastructure strengths into coordinated execution.

Priority areas include earlier infrastructure planning, stronger site and project readiness, clearer pathways from projected demand to reliably served load, expanded efficiency and flexibility, and sustained coordination among utilities, customers, policymakers, communities, technology providers and economic development organizations.

HETI is advancing this work through research and convening efforts focused on Houston’s evolving power needs and economic competitiveness.

The 2026 Power Summit reinforced Houston’s strong foundation for power-intensive growth and the importance of aligning investment, reliability, flexibility and regional coordination around the next generation of economic opportunity.

———

This article originally appeared on the Greater Houston Partnership's Houston Energy Transition Initiative blog. HETI exists to support Houston's future as an energy leader. Gain more insights from HETI’s Energy Efficiency and Demand Response Report.